- Lymphatic System and Diseases
- Effects of Radiation Exposure
- Nonmelanoma Skin Cancer Studies
- Breast Cancer Treatment Studies
- Machine Learning in Bioinformatics
- Fractal and DNA sequence analysis
- Cancer survivorship and care
- Diabetes and associated disorders
- Head and Neck Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Genomics and Phylogenetic Studies
- Cancer Treatment and Pharmacology
- Chemotherapy-related skin toxicity
- Diabetes Management and Research
- Pancreatic function and diabetes
- Palliative Care and End-of-Life Issues
- Thyroid Cancer Diagnosis and Treatment
- Health and Medical Research Impacts
- AI in cancer detection
- Chemotherapy-induced cardiotoxicity and mitigation
- Thyroid and Parathyroid Surgery
- Gene expression and cancer classification
- RNA and protein synthesis mechanisms
- Lung Cancer Treatments and Mutations
- Ultrasound and Hyperthermia Applications
Princess Margaret Cancer Centre
2016-2025
University of Toronto
2014-2025
University Health Network
2014-2025
Yale University
2020-2023
University of Oklahoma Medical Center
2023
Brigham and Women's Hospital
2023
Yale New Haven Hospital
2023
Sunnybrook Health Science Centre
2021-2022
Oxford University Hospitals NHS Trust
2022
Health Sciences Centre
2021
Problematic behaviors are a significant reason for relinquishment, and relinquished dogs more likely to have problem behaviors. This study utilized standardized surveys of owners (companion animal guardians) relinquishing their shelters dog visiting vaccination clinics. "Relinquishing" "continuing" were asked questions in the following categories: demographic information, training methods tools, frequencies which engaged problematic behaviors, attachment dogs. "Relinquishers" also provide...
Advances in radiation techniques have enabled the precise delivery of higher doses radiotherapy to tumours, while sparing surrounding healthy tissues. Consequently, incidence toxicities has declined, and will likely continue improve as further evolves. Nonetheless, ionizing elicits tissue-specific that gradually develop into radiation-induced fibrosis, a common long-term side-effect radiotherapy. Radiation fibrosis is characterized by an aberrant wound repair process, which promotes...
In the present work, we set out to comprehensively describe unmet supportive care and information needs of lung cancer patients.This cross-sectional study used Supportive Care Needs Survey Short Form 34 (34 items) an informational survey (8 items). Patients with primary in any phase survivorship were included. Demographic data treatment details collected from medical charts participants. The determined overall by domain. Univariable multivariable regression analyses performed determine...
A locus on human chromosome 11q23 tagged by marker rs3802842 was associated with colorectal cancer (CRC) in a genome-wide association study; this finding has been replicated case-control studies worldwide. In order to identify biologic factors at that are related the etiopathology of CRC, we used microarray-based target selection methods, coupled next-generation sequencing, study 103 kb locus. We genotyped 369 putative variants from 1,030 patients CRC (cases) and 1,061 individuals without...
Abstract Almost all genomic studies of breast cancer have focused on well-established tumours because it is technically challenging to study the earliest mutational events occurring in human epithelial cells. To address this we created a unique dataset samples ductoscopically obtained from ducts leading carcinomas and matched opposite side nipple. Here, demonstrate that perturbations mRNA abundance, with increasing proximity tumour, cannot be explained by copy number aberrations. Rather,...
<h3>Importance</h3> Approximately 1 in 5 patients with breast cancer who undergo axillary lymph node dissection will develop lymphedema. To appropriately triage and monitor these for timely diagnosis treatment, robust risk models are required. <h3>Objective</h3> evaluate the prognostic value of mammographic density estimating lymphedema severity. <h3>Design, Setting, Participants</h3> This study collected data from July 16, 2018, to March 3, 2020, electronic health records Cancer...
Importance Secondary lymphedema is a common, harmful side effect of breast cancer treatment. Robust risk models that are externally validated needed to facilitate clinical translation. A published model used 5 accessible factors predict the development cancer–related lymphedema; this included patient’s mammographic density as novel predictive factor. Objective To investigate external validity previously reported 5-factor by applying it an independent cohort patients with cancer. Design,...
Radiation dermatitis (RD) is a significant side effect of radiotherapy experienced by breast cancer patients. Severe symptoms include desquamation or ulceration irradiated skin, which impacts quality life and increases healthcare costs. Early identification patients at risk for severe RD can facilitate preventive management reduce symptoms. This study evaluated the utility subjective objective factors, such as patient-reported outcomes (PROs) serum cytokines, predicting in The performance...