A5010238792- Adipose Tissue and Metabolism
- Nerve injury and regeneration
- Monoclonal and Polyclonal Antibodies Research
- Adipokines, Inflammation, and Metabolic Diseases
- Neuroscience and Neuropharmacology Research
- Memory and Neural Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Medicinal Plants and Neuroprotection
- Water Treatment and Disinfection
- Bacteriophages and microbial interactions
- Apelin-related biomedical research
- Biochemical effects in animals
- Mast cells and histamine
- Biosensors and Analytical Detection
- Boron Compounds in Chemistry
- Medicinal Plant Extracts Effects
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Estrogen and related hormone effects
- Phytoestrogen effects and research
- Legionella and Acanthamoeba research
- Vibrio bacteria research studies
- Mesenchymal stem cell research
- Menopause: Health Impacts and Treatments
- Metabolism and Genetic Disorders
- Stress Responses and Cortisol
Guilan University of Medical Sciences
2012-2021
University of Guilan
2010-2012
Indiana University Bloomington
1993
Indiana University School of Medicine
1993
Idaho State University
1988
Nanobodies show attractive characteristics for tumor targeting in cancer diagnosis and therapy. A radiolabeled nanobody binding the prostate-specific membrane antigen (PSMA) could offer a noninvasive strategy to select prostate patients eligible PSMA-targeted therapies. We here describe generation, production vivo evaluation of anti-PSMA nanobodies. were derived from heavy-chain-only antibodies, raised immunized dromedaries. Binding evaluated through ELISA flow cytometry. Selected nanobodies...
The present study aims to evaluate the effect of bone marrow mesenchymal stem cells (MSCs) grafts on cognition deficit in chemically and age-induced Alzheimer's models rats. In first experiments aged animals (30 months) were tested Morris water maze (MWM) divided into two groups: impaired memory unimpaired memory. Impaired groups cannulated bilaterally at CA1 hippocampus for delivery (<svg style="vertical-align:-2.29482pt;width:87.162498px;" id="M1" height="16.8375" version="1.1" viewBox="0...
To study the influence of aerobic exercise training on brain-derived neurotrophic factor (BDNF), insulin resistance, and lipid profile in middle-aged men diagnosed with metabolic syndrome (MetS).This is an experimental repeated measure study.Subjects participated programs (18 sessions 25-40 minutes per session) Guilan University gymnasium court.A total 21 (50-65 years old) MetS participated.We randomly divided into control groups. The group followed program sessions, 3/wk) at 50% to 60%...
Here, we studied the beneficial effects of aerobic exercise on metabolic syndrome components, cognitive performance, brain derived neurotrophic factor (BDNF) and irisin in ovariectomized rats with different serum vitamin D (Vit D) status. Eighty female wistar were divided into 2 groups sham operated (sham, n = 8), (OVX, 72). Then OVX 9 receiving combination protocol low dose Vit (OVX + EXE LD), high HD), deficiency − D), Veh). Also non exercised Veh Veh) included. After months related...
Objective The aim of this experimental study was to investigate the effects exercise training on visceral fat and adiponectin levels in ovariectomized (OVX) rats.Method Female Wistar rats were divided into OVX (n = 20) sham-operated control (SHAM; n 8) groups. subdivided a sedentary (OVX-SED; 10) an (OVX-EX; group. consisted 8 weeks aerobic (26 m/min, 5 days/week, 60 min/day, 10% slope).Results In rats, body weight 21% greater (255.2 ± 9.31 vs. 211.63 3.23; p < 0.01) 29% (10.87 0.66 8.43...
Ovarian hormones have been shown to regulate body weight, intra-abdominal fat accumulation and plasma level of cytokines. The aim this study was investigate the effect estrogen replacement therapy on visceral adipose tissue, apelin, lipid profiles, glucose in ovariectomized (OVX) rats. Thirty female Wistar rats were divided into OVX (n = 20) sham 10) groups. subdivided (OVX+est; n receiving 17 β-estradiol valerates (30 µg/kg, s.c., 5 day/week, for eight weeks), vehicle control group sesame...
The present study was designed to the preventive effect of hydroalcoholic extract ripe pistachio hulls (RPH) in elevated plus maze model anxiety. One hundred twenty female wistar rats their estrous cycle were divided into 15 groups 8 each and received various concentrations RPH except control groups. Elevated used measure level Percentage time spent open arms (%OAT), percentage number entries (%OAE), locomotor activity, closed (CAT), (CAE) measured compared. Dose-response experiments showed...
Prostate-specific membrane antigen (PSMA), a type II integral glycoprotein, is highly overexpressed in all forms of prostate cancer tissues. It has also been demonstrated wide range neovasculature non-prostatic solid tumors, including bladder, pancreas, lung, kidney, colorectal, and gastric cancers. Given the unique expression PSMA, it considered an alluring target for antibody-based imaging therapy cancer. In present study, production characterization camel heavy chain antibodies (HCAbs)...
Background: It has been known that Brain-Derived Neurotrophic Factor (BDNF) is involved in neural survival and long term memory (LTM).Here we hypothesized BDNF as a potent neurotrophic factor might modulate amnestic effect induced by morphine. Objectives:The aim of this study was to examine whether infusion exogenous the CA1 regions dorsal hippocampi could ameliorate impairment morphine.Materials Methods: Forty rats were divided into 5 groups for dose response morphine (2.5, 5, 7.5 10 mg/kg...