The recent introduction of sachet water to consumers was provide safe, hygienic and affordable instant drinking the public. Although this is a laudable idea current trends seem suggest that could be route transmission enteric pathogens.To assess safety water.Twenty seven different brands 500ml samples randomly selected purchased from various vendors in Accra were subjected microscopic examinations determine presence parasitic protozoa. study carried out between January May 2005.Seventy-seven...

ABSTRACT Genotyping of human rotaviruses was performed on 312 rotavirus-positive samples collected from 2,205 young children with diarrhea in the Upper East District Ghana, a rural community. Of 271 (86.9%) rotavirus strains that could be VP7 (G) or VP4 (P) characterized, 73 (26.9%) were G9 specificity. The predominant genotype G9P[8], which constituted 79.5% all detected, followed by G9P[6] (12.3%), G9P[10] (2.7%), and G9P[4] (1.3%). mixed P types 2.7% found study. All G9P[8] had long RNA...

Human Papillomavirus (HPV) infections have been shown to be a necessary risk factor for the development of cervical cancer. However, HPV genotype distribution varies geographically, both in type and relative prevalence. In order ensure successful introduction available vaccines, there is need identify pre-vaccination prevalence Ghana extent single multiple-infections.

Determining the high-risk human papillomavirus (HR-HPV) genotypes burden in women with and without cervical cancer afford a direct comparison of their relative distributions. This quest is fundamental to implementing future population-based prevention strategy Ghana. We estimated risk by HPV genotypes, vaccine-preventable proportion diagnosed

Summary We measured the type‐specific incidence of paediatric rotavirus diarrhoea in an area northern Ghana. Over 1 year, 1717 episodes were identified, which 677 (39%) positive for rotavirus. Risk factors infection included old age, wasting, high Vesikari score and episode occurring dry season. Rotavirus‐positive tended to be more acute, causing vomiting greater dehydration, likely require hospitalization. The was 0.089 per person‐year all diarrhoea, 0.035 diarrhoea. observed decreased...

This study was designed to investigate whether household cockroaches harbor cephalosporin-resistant enterobacteria that share resistance determinants with human inhabitants. From February through July 2016, whole cockroach homogenates and fecal samples from 100 households were cultured for (CRe). The CRe examined plasmid-mediated AmpC, ESBL, carbapenemase genes; antibiotic susceptibility patterns; conjugative transfer of mechanisms. Clonal associations between determined by multi-locus...

Cervical cancer is the most common gynaecologic in Ghana where it also second cause of all female cancers. A number vaccines are available to provide both individual and population-level protection against persistent infection with high-risk human papillomaviruses (HR-HPV) reduce burden cervical cancer. Data on epidemiology vaccine-preventable scant.

Abstract Background Progress toward malaria elimination is increasing as many countries near zero indigenous cases. In settings nearing elimination, interventions will be most effective at interrupting transmission when targeted the residual foci of transmission. These may missed due to asymptomatic infections. To solve this problem, World Health Organization recommends reactive case detection (RACD). This study was conducted identify individuals with malaria, their predisposing risk factors...

Sixty-seven rotavirus-positive fecal samples, collected between January and April 1999, from children with diarrhea in the Upper East Region of Ghana were examined for rotavirus VP7 VP4 types. Sufficient viral RNA could be obtained 46 (68.7%) samples all isolates had short electrophoretic pattern typed as subgroup I rotaviruses by ELISA. Three strains G8 specificity identified first time Ghana. G P typing PCR two distinct strains, P[6]G2 (50%) P[6]G8 (4.3%). Eighty-two percent (n = 38)...

Cyperus esculentus L, is a minor but important crop in Ghana. They are noted mostly by their aphrodisiac properties among others. The nuts often eaten raw as an unprocessed snack due to its rich flavour and texture. Though raw, the sometimes handled unhygienically, posing public health threat. This study therefore aimed at determining level distribution of parasitic bacterial contaminants associated with it sold. Four types intestinal parasites were identified, most prevalent was...

Introduction: Helicobacter pylori is a gram-negative urease-producing bacteriumcausally linked with gastritis, peptic ulcer disease and gastric adenocarcinoma. Infection more frequent acquired at an earlier age in developing countries compared to European populations.The incidence of infection dyspeptic Ghanaian patients was 75.4 %. However, epidemiological factors associated vary across populations.

As part of malaria characterization study in the South-Tongu district Ghana, current was conducted to explore relationships between malaria, schistosomiasis, soil transmitted helminths and malnutrition riparian community settings that had hitherto encountered episodes mass deworming exercises. School-age children were enrolled a cross-sectional from April through July 2012. Stool urine samples examined respectively for Schistosoma haematobium. Blood analyzed parasites haemoglobin (Hb)...

Vaccination is the most effective preventive strategy against rotavirus disease. Regional differences in prevalent genotypes may affect vaccine efficacy. Pre-vaccine surveillance for burden of disease, genotypes, and association between disease intussusceptions helps monitoring impact vaccination.A prospective study was conducted from January 2008 to December 2009 children younger than five years hospitalized longer 24 hours with acute gastroenteritis. Data on confirmed cases intussusception...

Abstract Ghana does not have a universal population-based cervical cancer screening program and there is very limited information about the distribution of epithelial cell lesions. This study provides evidence that moderately high prevalence precancerous lesions exists among unscreened women in Kumasi. The abnormalities cross-section attending for first time suburb from 2011 to 2014 was studied. Cervical smears were prepared examined independently by 2 cytotechnologists confirmed...

Background Cervical cancer ranks as the fourth most common among women, with 662,301 new cases and 348,874 deaths reported in 2022. The majority of disease burden occurs low- middle-income countries. In Ghana, there were 3072 1815 While human papillomavirus (HPV) infection, a key cause for cervical cancer, resolves individuals, it can progress to some. This has led research into other factors that may, conjunction HPV, increase risk progression. Improving knowledge factors, screening will be...

ABSTRACT Vulvovaginal candidiasis (VVC) is a common fungal infection, affecting approximately 75% of women at least once in their lifetime. Candida albicans the predominant pathogen, responsible for 85%–90% symptomatic cases. This study assessed prevalence and antifungal susceptibility patterns species isolated from pregnant with VVC to determine species-specific resistance trends treatment implications. A cross-sectional was conducted between November 2020 July 2023 Ho Teaching Hospital...

An epidemiological study of rotavirus infection was conducted on specimens collected from patients with gastroenteritis and domiciled in the rural Upper Eastern Region Ghana during 1998. Fifty isolates, randomly selected 165 human group A rotavirus-positive samples, were G P characterized by a reverse transcription (RT)-PCR assay using seminested multiplex method. Rotaviruses G3 genotype found to be predominant strain (78%), followed G2 (14%) G1 (2%). Mixed infections, as shown combinations...

Helicobacter pylori infection is prevalent in Ghana. The development of gastro-duodenal disease dependent on virulence the infecting strain, host susceptibility and environmental factors. cagA vacA strains induce more inflammation, ulceration oncogenesis. Here, for first time we present data H. genes their association with A total 159 patients dyspepsia at Korle-Bu Teaching Hospital, Accra, were investigated urease-CLO, which 113 (71.1%) positive. Genomic DNA was extracted from antral...

Cervical cancer is a largely preventable disease mediated by persistent infection with high-risk Human Papillomaviruses (Hr-HPV). There are now three approved vaccines against the most common HPV genotypes. In Ghana, mortality due to cervical on rise, absence of an organized and effective prevention control program. Data circulating genotypes important for studying likely impact mass introduction vaccination female population before sexual debut. High prevalence has been reported in Female...

The incidence of calicivirus infection in Ghana and many other African countries is not known. Thirteen (15.9%) the 82 diarrhoeic stool samples tested for caliciviruses were positive noroviruses (NoVs). NoVs present all age groups detected only during diarrhoea peak that coincided with rotavirus season. Ten (76.9%) NoV genogroup II (GII) remaining three (23.1%) I (GI) NoVs. predominant GII was GII-4 (60%, 6/10). Three determined to be recombinants GII-8/GII-14 as deduced from sequencing...

Persistent hyperglycaemia is a hallmark of Diabetes Mellitus (DM). It causes increased production free radicals, especially reactive oxygen species (ROS), - resulting in oxidative stress. Reactive Oxygen Species have been implicated the development haematological complications patients with diabetes. Superoxide Dismutase (SOD) one most effective antioxidant enzyme defense systems against radicals.From February through May 2014, we assessed relationship between stress and profiles among...