A5062653752- Fecal contamination and water quality
- Escherichia coli research studies
- Parasitic Infections and Diagnostics
- Viral gastroenteritis research and epidemiology
- Antibiotic Resistance in Bacteria
- Pharmaceutical and Antibiotic Environmental Impacts
- Urban Stormwater Management Solutions
- Aquaculture disease management and microbiota
- Salmonella and Campylobacter epidemiology
- Vibrio bacteria research studies
- Prion Diseases and Protein Misfolding
- Flood Risk Assessment and Management
- Amoebic Infections and Treatments
- Water Treatment and Disinfection
- Bacteriophages and microbial interactions
- Water Systems and Optimization
- Mycobacterium research and diagnosis
- Wastewater Treatment and Reuse
- Parasitic infections in humans and animals
- Immune cells in cancer
- SARS-CoV-2 detection and testing
- Avian ecology and behavior
- Zebrafish Biomedical Research Applications
- Immune Response and Inflammation
- Enterobacteriaceae and Cronobacter Research
University of Alberta
2015-2024
University of Calgary
2002-2023
Provincial Laboratory of Public Health
2009-2017
Alberta Health Services
2011-2016
Faculty of Public Health
2012
Environment and Climate Change Canada
2002
To assess the removal of viruses through multiple steps wastewater treatment in a full-scale municipal plant Alberta, Canada.Samples were collected after each five for period 16 months. The amount and their infectivity analysed using real-time quantitative PCR (qPCR) integrated viral cell culture (ICC), respectively. Bacterial indicator Escherichia coli was also tested membrane filtration. Seven including Norovirus (NoV), Rotavirus (RV), Sapovirus (SaV), Astrovirus (AsV), Adenovirus (AdV),...
Escherichia coli has been proposed to have two habitats-the intestines of mammals/birds and the nonhost environment. Our goal was assess whether certain strains E. evolved toward adaptation survival in wastewater. Raw sewage samples from different treatment plants were subjected chlorine stress, ∼59% surviving found contain a genetic insertion element (IS30) located within uspC-flhDC intergenic region. The positional location IS30 not observed across library 845 isolates collected various...
ABSTRACT Establishing the risk of human infection is one goals public health. For bacterial pathogens, virulence and zoonotic potential can often be related to their host source. Escherichia coli bacteria are common contaminants water associated with recreation consumption, many strains pathogenic. In this study, we analyzed three promoter-containing intergenic regions from 284 diverse E. isolates in an attempt identify molecular signatures specific types. Promoter sequences controlling...
SUMMARY To determine whether drinking water contaminated with antimicrobial-resistant E. coli is associated the carriage of resistant , selected households sending samples to Ontario and Alberta laboratories in 2005–2006 were asked participate a cross-sectional study. Household members aged ⩾12 years complete questionnaire submit rectal swab. In 878 individuals, 41% carried strain 28% multidrug-resistant strain. The risk was 1·26 times higher for users . Other factors included international...
Chlorine treatments are used in water and wastewater sanitation; the resistance of Escherichia coli to chlorine is thus concern public health. We show that a genetic island termed locus heat (LHR) protects E. not only against but also other oxidizing chemicals, adding our knowledge tools by resist stress. Specific detection oxidation different cellular targets combination with cloning fragments LHR provided insight into mechanisms protection demonstrated protect targets. In , presence...
We previously demonstrated the existence of naturalized strains E. coli in wastewater and herein perform an in-depth comparative whole genome analysis these (n = 17). Fourteen Canadian strains, isolated from geographically separated treatment plants, were virtually identical at core ≥96% similar level, suggesting clonal-relatedness among isolates. Remarkably, shown to be extremely Switzerland, a global distribution strains. The genomes three other more diverse but very isolates collected...
In mammals, the increased generation of prostaglandins (PG) during onset inflammatory responses and activation immune cell types has been attributed to induction a novel cyclo-oxygenase (COX) isoform, termed COX-2, which is distinct from well-characterized constitutive activity (COX-1). Goldfish (Carassius auratus) macrophages exposed bacterial lipopolysaccharide leucocyte-derived macrophage-activating factor(s) showed significant increase in major COX product, PGE2, within first 6 h...
The occurrence of waterborne pathogens was investigated at three drinking water intakes located about 2 km offshore in Lake Ontario. Water sampling conducted over 3 years for Campylobacter spp., Cryptosporidium Giardia cultivable enteric viruses, and quality parameters. All were detected the source each treatment plant (WTP1 to WTP3), although relatively low frequencies concentrations. most common pathogen, occurring 36% samples from influent WTP1 (n = 46), with a maximum concentration 0.70...