Hala Badr Khalil

ORCID: 0000-0003-2714-2327
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About
Contact & Profiles
Research Areas
  • Plant Disease Resistance and Genetics
  • Plant-Microbe Interactions and Immunity
  • Wheat and Barley Genetics and Pathology
  • Plant Stress Responses and Tolerance
  • Polysaccharides and Plant Cell Walls
  • Plant Pathogens and Fungal Diseases
  • Yeasts and Rust Fungi Studies
  • Parasites and Host Interactions
  • Fungal and yeast genetics research
  • Plant Genetic and Mutation Studies
  • Plant pathogens and resistance mechanisms
  • Plant Pathogenic Bacteria Studies
  • Plant Pathogens and Resistance
  • Light effects on plants
  • Mycorrhizal Fungi and Plant Interactions
  • Lipid metabolism and biosynthesis
  • Bacteriophages and microbial interactions
  • Fungal Plant Pathogen Control
  • Rabies epidemiology and control
  • Plant responses to water stress
  • Chromium effects and bioremediation
  • Plant Reproductive Biology
  • Medicinal plant effects and applications
  • Plant Gene Expression Analysis
  • Pineapple and bromelain studies

Ain Shams University
1998-2025

King Faisal University
2023-2025

Concordia University
2011-2021

Agriculture and Agri-Food Canada
2015-2020

Al-Baath University
2008-2018

Summerland Research and Development Centre
2016-2017

Cairo University
1998

Abstract Three members of the Puccinia genus, Pucciniatriticina (Pt), P. striiformis f.sp. tritici (Pst), and graminis (Pgt), cause most common often significant foliar diseases wheat. While similar in biology life cycle, each species is uniquely adapted specialized. The genomes Pt Pst were sequenced compared to that Pgt identify distinguishing gene content, determine variation among wheat rust pathogens, other fungi, basidiomycetes, genes significance for infection. had largest genome...

10.1534/g3.116.032797 article EN cc-by G3 Genes Genomes Genetics 2017-02-01

Lung cancer remains a leading cause of cancer-related mortality worldwide. Despite advancements in current therapies, the development drug resistance and need for improved treatment outcomes necessitate exploration novel therapeutic approaches. This study aimed to investigate synergistic anti-cancer effects Melittin, bee venom peptide, combination with Erlotinib, an EGFR inhibitor, non-small cell lung (NSCLC). The evaluated combined Melittin Erlotinib on A549 NSCLC cells. Cell viability,...

10.3390/ijms26072903 article EN International Journal of Molecular Sciences 2025-03-22

Plant fungal pathogens cause substantial economic losses through crop yield reduction and post-harvest storage losses. The utilization of biocontrol agents presents a sustainable strategy to manage plant diseases, reducing the reliance on hazardous chemical. Recently, Pichia kudriavzevii has emerged as promising agent because its capacity inhibit growth, offering potential solution for disease management.Two novel strains, Pk_EgyACGEB_O1 Pk_EgyACGEB_O2, were isolated from olive brine...

10.1186/s12866-023-03047-w article EN cc-by BMC Microbiology 2023-11-18

Malaysia ranks among the world’s top 20 pineapple producers, driven by success of MD2 variety in meeting domestic and international demand. However, postharvest losses due to pathological diseases remain a challenge. Black rot, major disease, causes significant economic pineapples. Despite its presence various cultivars, aetiology, specifically pineapples remains unclear. This study was conducted identify principal causative pathogen black rot disease from three different regions. In...

10.3389/fmicb.2024.1514235 article EN cc-by Frontiers in Microbiology 2025-01-21

Powdery mildew, caused by Blumeria graminis f. sp. hordei (Bgh), severely impacts global barley Hordeum vulgare L. (Hv) production. This investigation evaluated Egyptian genotypes to identify novel resistance sources and molecular markers for breeding programs. Phenotypic assessments at the seedling (growth stage, GS 32) adult plant (GS 55–59) stages under controlled field conditions, combined with SSR marker analysis, revealed distinct profiles. Genotypes Giza 123, 125, G8 exhibited strong...

10.3390/plants14081231 article EN cc-by Plants 2025-04-17

One of the most important evolutionary processes in plants is polyploidization. The combination two or more genomes one organism often initially leads to changes gene expression and extensive genomic reorganization, compared parental species. Hexaploid triticale (x Triticosecale) a synthetic hybrid crop species generated by crosses between T. turgidum Secale cereale. Because recent polyploid it an model for studying genome evolution following Molecular studies have demonstrated that sequence...

10.1186/s12864-015-1480-x article EN cc-by BMC Genomics 2015-04-09

The caleosin genes encode proteins with a single conserved EF hand calcium-binding domain and comprise small gene families found in wide range of plant species. Some members the family have been shown to be upregulated by environmental stresses including low water availability high salinity. Caleosin 3 from wheat has interact α-subunit heterotrimeric G proteins, act as GTPase activating protein (GAP). This study characterizes size diversity related species differential tissue-specific...

10.1186/1471-2164-15-239 article EN cc-by BMC Genomics 2014-03-27

Understanding the role of cysteine-rich receptor-like kinases (CRKs) in plant defense mechanisms is crucial for enhancing wheat resistance to leaf rust fungus infection. Here, we identified and verified 164 members CRK gene family using Triticum aestivum reference version 2 collected from international genome sequencing consortium (IWGSC). The proteins exhibited characteristic features CRKs, including presence signal peptides, cysteine-rich/stress antifungal/DUF26 domains, transmembrane...

10.3390/plants12162932 article EN cc-by Plants 2023-08-14

Summary Reactive oxygen species (ROS) play an important role during host–pathogen interactions and are often indication of induced host defence responses. In this study, we demonstrate for the first time that Puccinia triticina ( Pt ) generates ROS, including superoxide, H 2 O hydroxyl radicals, wheat infection. Through pharmacological inhibition, found ROS critical both urediniospore germination pathogenic development on wheat. A comparative RNA‐Seq analysis different stages infection...

10.1111/1462-2920.15063 article EN cc-by-nc-nd Environmental Microbiology 2020-05-11

Abstract Background Basil ( Ocimum sp.) exhibits significant morphological and genetic diversity. This variation provides an opportunity to identify novel traits that can be used in breeding programs improve the productivity, quality, disease resistance of basil plants. The integration data for varieties our understanding biodiversity, conservation, programs. Results In 2019, we conducted a comprehensive investigation on 25 landraces collected from 12 Egyptian governorates explore their...

10.1186/s43088-023-00408-2 article EN cc-by Beni-Suef University Journal of Basic and Applied Sciences 2023-07-28

Cadmium (Cd) toxicity is a serious threat to agronomic crop productivity worldwide. It raises severe concerns about the food and nutrient security required meet demands of rapidly growing population, while also creating grave challenges for agriculture. Silicon (Si) strigolecton (SL) are reported impart multiple benefits plants exposed abiotic stress. Therefore, current experiment was performed evaluate effects silicon (4.0 mM) (20 µM) on amelioration cadmium (25 mg kg−1 soil) stress in...

10.3390/agronomy13092352 article EN cc-by Agronomy 2023-09-10

Background/Objectives: The phytosulfokine receptor (PSKR) gene family plays a crucial role in regulating plant growth, development, and stress response. Here, the PSKR was characterized Triticum aestivum L. study aimed to bridge knowledge gaps clarify functional roles of TaPSKRs create solid foundation for examining structure, functions, regulatory aspects. Methods: investigation involved genome-wide identification PSKRs through collection chromosomal assignment, followed by phylogenetic...

10.3390/genes15101306 article EN Genes 2024-10-09

Abstract Three members of the Puccini genus, P. triticina ( Pt ), striiformis f.sp. tritici Pst and graminis Pgt cause most common often significant foliar diseases wheat. While similar in biology life cycle, each species is uniquely adapted specialized. The genomes were sequenced compared to that identify distinguishing gene content, determine variation among wheat rust pathogens, other fungi basidiomycetes, genes significance for infection. had largest genome three, estimated at 135 Mb...

10.1101/060665 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2016-06-24

HomePlant DiseaseVol. 103, No. 3First Report of Tomato "Big Bud" Disease in Syria Caused by 'Candidatus Phytoplasma trifolii'-Related Strain PreviousNext DISEASE NOTES OPENOpen Access licenseFirst StrainH. Khalil, R. N. Yousef, V. Girsova, D. Z. Bogoutdinov, T. B. Kastalyeva, and S. AldenkaweH. KhalilAl-Baath University, Homs, Syria; , YousefAl-Baath GirsovaAll-Russian Research Institute Phytopathology, Bolshie Vyasiomy, Moscow Region, 143050 Russia; BogoutdinovSamara State Agricultural...

10.1094/pdis-06-18-1057-pdn article EN other-oa Plant Disease 2018-10-11

D ECOLORIZATION of textile reactive azo dyes, blue and yellow, by 15 bacterial isolates collected from Egyptian arid soil was investigated.Of these, S8 isolate revealed a highest decolorization performance.Here, we identified on molecular level based type I chaperonin universal target sequence (cpn60).The most similar DNA to the for Klebsiella oxytoca partial CDS (AB008147.1)coding GroES GroEL chaperon homologues (acronyms cpn60) with 88% similarity.The impact numerous exterior parameters...

10.21608/ejm.2019.15326.1107 article EN Egyptian Journal of Microbiology 2019-09-10
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