A5103387377- Vehicle Noise and Vibration Control
- Gear and Bearing Dynamics Analysis
- Mechanical Engineering and Vibrations Research
- Tribology and Lubrication Engineering
- Acoustic Wave Phenomena Research
- Hydraulic and Pneumatic Systems
- Vibration and Dynamic Analysis
- Brake Systems and Friction Analysis
- Effects of Vibration on Health
- Structural Health Monitoring Techniques
- Vibration Control and Rheological Fluids
- Dynamics and Control of Mechanical Systems
- Railway Engineering and Dynamics
- Magnetic Bearings and Levitation Dynamics
- Vehicle Dynamics and Control Systems
- Adhesion, Friction, and Surface Interactions
- Aerodynamics and Fluid Dynamics Research
- Open Education and E-Learning
- Soil Mechanics and Vehicle Dynamics
- Enzyme Catalysis and Immobilization
- Iterative Learning Control Systems
- Control Systems in Engineering
- Structural Engineering and Vibration Analysis
- Streptococcal Infections and Treatments
- Bladed Disk Vibration Dynamics
Teva Pharmaceuticals (United States)
2023-2025
Indian Veterinary Research Institute
2025
Clemson University
2022-2023
Northwell Health
2023
Siksha O Anusandhan University
2023
Indian Institute of Technology Palakkad
2022
Sardar Patel Medical College
2022
MIT World Peace University
2022
Manipal University Jaipur
2022
The Ohio State University
2010-2021
“Children are not tiny adults” is an adage commonly used in pediatrics to emphasize the fact that children often have different physiological responses sickness and trauma compared adults. However, despite widespread acceptance of this concept, diagnostic blood testing excellent example clinical care yet customized needs children, especially newborns. Cumulative loss resulting from does typically impact critically ill adult patients, but can quickly escalate leading iatrogenic anemia related...
Sliding friction between meshing teeth is one of the primary excitations for noise and vibration in geared systems. Yet, there exist very limited studies on this topic. This paper proposes new modeling strategies incorporating dynamic analysis a gear pair. First, some tribological issues are discussed estimation forces under different operating conditions. Second, procedures results compared linear time-invariant, time-varying non-linear formulations. Criteria such as energy balance, system...
Nonlinear properties of a generic hydraulic mount with an inertia track are identified and characterized by using experimental analytical approaches. A low-frequency lumped-parameter mathematical model the is developed over 1 to 50 Hz, based on measured nonlinear system parameters such as steady-state fluid resistances chamber compliances. New experiments specifically designed for this study also described. The effect temperature dynamic discussed briefly. When compared signals under...
We propose a new control strategy for on-off valve controlled pneumatic actuators and robots with focus on the position accuracy. A mathematical model incorporating process nonlinearities nonlinear mechanical friction has been developed to characterize actuator dynamics; this few simplifications is then used design controller. In our scheme, one held open other operated under pulse width modulation mode simulate proportional control. An inner loop utilizing proportional-plus-integral formed...
Sound radiation characteristics of an annular disk with application to the computer are examined analytically. The far-field and impedance approaches employed calculate radiated sound a vibrating at its elastic or rigid body modes. Modal power is formulated by approximating structural modal functions expressed in terms series wave number. Predictions show that axisymmetric vibration modes more efficient radiators compared those asymmetric have same number nodal circles. Numerical results...
This paper proposes a new analytical model for helical gears that characterizes the contact plane dynamics and captures velocity reversal at pitch line due to sliding friction. First, tooth stiffness density function along lines is calculated by using finite element code. Analytical formulations are then derived multidimensional mesh forces moments. Contact zones multiple pairs in identified, associated integration algorithms derived. A 12-degree-of-freedom, linear time-varying with friction...
The scope of this article is limited to the torsional driveline system a front-engine front-wheel type vehicle. A reduced-order model manual transmission (with third gear engaged and fifth unloaded) developed on basis modal characteristics. simplified nonlinear mathematical then proposed with focus multi-staged clutch damper properties such as asymmetric transition angles pre-loads. drag torque estimated under two engine conditions (wide-open throttle coast) by assuming that vehicle in...
Objectives: TEV-53408 is a human monoclonal antibody that binds to and neutralizes interleukin-15 (IL-15), which involved in T cell natural killer (NK) homeostasis immune-mediated diseases. currently being evaluated celiac disease. The objectives of this analysis were characterize the pharmacodynamic (PD) effect on NK counts, based data collected during Phase 1, first-in-human (FIH) study 114 healthy participants, further predict PK/PD signature patients for various indications. Methods: A...
Objectives: TEV-53408 is a human monoclonal antibody that binds to and neutralizes interleukin 15 (IL-15) currently being evaluated in celiac disease. The objective of this presented analysis was develop population pharmacokinetics/pharmacodynamics (PK/PD) model describe the time course free serum IL-15 following both single multiple subcutaneous (SC) doses healthy participants.Methods: Data from 115 participants across 8 dose levels including placebo Phase 1 first-in-human study used for...
Objectives: TEV-53408 is a human monoclonal antibody (mAb) that binds to and neutralizes interleukin-15 currently being evaluated in celiac disease. Utilizing data collected during the Phase 1 first-in-human (FIH) study healthy participants, this presented analysis sought characterize pharmacokinetics (PK) of further anticipate PK signature patients for various indications. Methods: Population modeling was used describe dynamics serum concentrations over time, several structural models were...
TV-46000 is a long-acting subcutaneous antipsychotic (LASCA) agent that combines risperidone and an innovative, copolymer-based drug delivery technology in suspension suitable for administration from prefilled syringe. The objective of the current analysis was to characterize pharmacokinetics (PK) based on pooled data phase 1 3 studies, further support clinical use aspects TV-46000. A population PK (popPK) model developed using obtained three studies (n = 267) two trials 425). sequential...
An analytical solution to the dynamic transmission error of a helical gear pair is developed by using single-degree-of-freedom model with piecewise stiffness functions that characterize contact plane dynamics and capture velocity reversal at pitch line. By assuming constant mesh density along lines, linear time-varying (with parametric excitations) obtained, where effect sliding friction quantified an effective term. The Floquet theory then used obtain closed-form solutions error, responses...