Sophie E. Vollenbrock

ORCID: 0000-0003-2721-663X
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About
Contact & Profiles
Research Areas
  • Esophageal Cancer Research and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Medical Imaging Techniques and Applications
  • Esophageal and GI Pathology
  • MRI in cancer diagnosis
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Diagnosis and Treatment
  • Neurological and metabolic disorders
  • Gastric Cancer Management and Outcomes
  • Folate and B Vitamins Research
  • Advanced MRI Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Heme Oxygenase-1 and Carbon Monoxide

OLVG
2021

The Netherlands Cancer Institute
2018-2020

Oncode Institute
2018-2019

Maastricht University Medical Centre
2019

Maastricht University
2019

Abstract Background Patients with a pathological complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) for oesophageal cancer may benefit from non-surgical management. The aim of this study was to determine the diagnostic performance visual assessment primary tumour nCRT on T2-weighted (T2W) and diffusion-weighted (DW) MRI. Methods locally advanced who underwent T2W- DW-MRI (1·5 T) before in two hospitals, between July 2013 September 2017, were included prospective study. Three...

10.1002/bjs.11094 article EN cc-by-nc-nd British journal of surgery 2019-02-25

Current delineation of the gross tumor volume (GTV) in esophageal cancer relies on computed tomography (CT) and combination with 18F-fluorodeoxyglucose (FDG) positron emission (PET). There is increasing interest integrating magnetic resonance imaging (MRI) radiation treatment, which can potentially obviate CT- or FDG-PET/CT-based delineation. The aim this study to evaluate feasibility target T2-weighted (T2W) MRI T2W including diffusion-weighted (T2W + DW-MRI) compared current-practice...

10.1016/j.adro.2019.04.004 article EN cc-by-nc-nd Advances in Radiation Oncology 2019-04-24

Planning SCOPE 2 mandated IMRT for both the standard and dose escalated arms, where 3DCRT had been used in 1 NeoSCOPE.75% of centres stated they former pre-trial, although at least 3 were only using upper 1/3 oesophageal cancers.79% our survey now use IMRT, including middle lower tumours.Type B planning algorithms, NeoSCOPE trial, 79.9% pre 83.3%.IGRT introduced a stomach filling protocol anatomical reproducibility.12.5% doing this which has risen to 50%.CBCT was IGRT trial.66.7% routinely...

10.1016/s0167-8140(18)31071-5 article EN cc-by-nc-nd Radiotherapy and Oncology 2018-04-01
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