A5000313019- Poxvirus research and outbreaks
- Herpesvirus Infections and Treatments
- Bacillus and Francisella bacterial research
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
Nigeria Centre for Disease Control
2020-2023
Laboratoire National de Référence
2023
The 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation. virus is related to an ongoing in Nigeria originally reported 2017, but the evolutionary path linking two remains unclear due a lack of genomic data between 2018, when exportations from were first recorded, 2022, began. Here, 18 viral genomes obtained patients across southern 2019-2020 reveal multiple lineages monkeypox...
Introduction Recent outbreaks of mpox are characterised by changes in the natural history disease, demographic and clinical characteristics cases, widening geographical distribution. We investigated role HIV other sexually transmitted infections (STIs) coinfection among cases re-emergence to inform national global response. Methods conducted a descriptive case–control study on 2017–2019 Nigerian outbreak. Mpox were age, sex area matched each with two randomly selected controls from...
Background: Human monkeypox is a rare zoonotic infection caused by an orthopoxvirus and characterized smallpox-like signs symptoms. Reported outbreaks have occurred mainly in rural rainforest areas of the Congo basin West Africa. In September 2017, Nigeria experienced resurgence monkeypox. Prior to this, last three cases recorded was 1978. Since then sporadic continued occur, especially Southern part country. We present descriptive epidemiology outbreak from 2017 June 2019. Methods...
Background: Recent outbreaks of monkeypox are characterized by changes in the natural history disease and demographic clinical characteristic cases coupled with widening geographical distribution. We investigated role HIV other Sexually Transmitted Infections (STI) co-infection among re-emergence to inform national global response.Methods: conducted a descriptive case-control study on 2017-2019 Nigerian outbreak. Monkeypox were age-, sex- area-matched each two randomly selected controls from...
Abstract The origin and hazardous potential of human mpox is obscured by a lack genomic data between the 2018, when exportations from Nigeria were recorded, 2022 global outbreak started. Here, 18 genomes patients across southern in 2019/20 reveal multiple lineages Monkeypox virus have achieved sustained human-to-human transmission, co-existing humans for several years accumulating mutations consistent with APOBEC3 activity suggesting now segregated its natural reservoir. Remarkably, three...