A5027245572- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Allergic Rhinitis and Sensitization
- Respiratory viral infections research
- Food Allergy and Anaphylaxis Research
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Respiratory and Cough-Related Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
- Eosinophilic Esophagitis
- Influenza Virus Research Studies
- Transplantation: Methods and Outcomes
- Congenital Anomalies and Fetal Surgery
- Organ Transplantation Techniques and Outcomes
- Pediatric health and respiratory diseases
- Dermatology and Skin Diseases
- Injury Epidemiology and Prevention
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Pharmaceutical studies and practices
- Gastroesophageal reflux and treatments
Ege University
2015-2025
Ege Üniversitesi Tıp Fakültesi Hastanesi
2014-2025
Sağlık Bilimleri Üniversitesi
2020-2025
University of Health Sciences Antigua
2025
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2023
ENT and Allergy
2023
Creative Commons
2020
Boston Children's Hospital
2015
University of the Aegean
2008
Pulmonary and Allergy Associates
2007-2008
The aim of this study was to investigate the caries risk asthmatics in relation dental plaque indices, salivary flow rate, pH and buffer capacity, saliva composition levels Streptococcus mutans compared with healthy subjects also evaluate these parameters within different groups according their medication, duration severity disease.The group composed 106 100 controls same age social background aged between 6 19-years-old. For examinations, World Health Organization criteria for indices...
Influenza virus is one of the most common respiratory pathogens for all age groups and may cause seasonal outbreaks. Our aim was to identify risk factors associated with severe clinical course including mortality in children influenza-related lower tract infection (LRTI).We conducted a retrospective study hospitalized influenza LRTI from 2008 2018. Data on demographic features, type, viral coinfection, primary secondary bacterial infections (SBIs), time onset antiviral treatment,...
The aim of our study was to evaluate the relationship between gastric emptying and gastroesophageal reflux (GER) in infants children.One hundred eight patients (pts) 3 months 5 years age (77 boys, 31 girls) with clinical suspicion GER disease were included study. Patients divided into 2 groups according range: group A, 0-2 (57 pts), B, 2-5 (51 pts) years. Each subgroups scintigraphic as GER-positive -negative. Cow's milk Tc-99m sulfur colloid radiotracer used. Gastric expressed half time...
Summary An improved understanding of the molecular mechanisms in asthma through exploring role microRNAs may offer promise to reveal new approaches for primary prevention and identification therapeutic targets childhood asthma. The goal this study is identify that play a pathogenesis pediatric age group. secondary analyze these according phenotype, atopic status, severity disease exacerbation. To our knowledge, first research project literature which studies relationship between microRNA...
Early diagnosis with newborn screening programs and prolonged life expectancy new treatment strategies have made cardiovascular disease (CVD) one of the important issues in cystic fibrosis (CF). In early stages CVD, it is difficult to recognize follow-up increased arterial stiffness conventional methods. Different measurement methods are needed. Therefore, this study, we aimed use measurements children CF. This a study examining changes CF by repeating hemodynamic [augmentation index (AIx)...
Inhalant abuse is a prevalent and often overlooked form of substance in adolescents. Chronic inhalant can damage respiratory, cardiac, renal, hepatic, neurologic systems. This study aims to determine the physiologic effects inhaling solvents on respiratory functions.The general health status subjects was assessed by history taking, physical examination questionnaire which designed show severity symptoms. Spirometry, ventilation/perfusion scintigraphy, high resolution computed tomography...
To determine whether high-flow nasal cannula oxygen (HFNCO) provided enhanced respiratory support in bronchiolitis than low-flow (LFO).We conducted a prospective, randomized controlled trial children between 1 and 24 months diagnosed with moderate-to-severe requiring therapy. Participants received LFO via face mask (6-10 L/min) or HFNCO (2 L/kg/min). Primary outcomes were the time that heart rate (HR) (RR) return to their normal range for age baseline clinical score (CRS) regress lower...
Asthma is a complex genetic disease. Genetic and functional characteristics of interleukin (IL)-1 support role as an asthma locus for the IL-1 family on chromosome 2q12-21. This study was performed to investigate relationship between polymorphisms IL-1beta promoter region -511C/T receptor antagonist (IL-1Ra) gene (IL-RN) bronchial in Turkish children. Children were divided into two groups: (1) (n=328) (2) healthy control (n=246). Polymerase chain reaction used resolve IL-1Ra intron 2...
Aim: Infections caused by respiratory viruses sometimes occur as epidemias or pandemias and are an important public health problem in the whole world.These viral agents may lead to severe diseases especially young children elderly.The aim of this study was determine seasonal distribution agent childhood infections our region. Material Methods:In study, nasopharyngeal swab sample obtained from 1 326 patients who presented Ege University, Medical Faculty Children's Hospital between 2002 2012...
Abstract With the increase in life expectancy, cardiovascular complications of cystic fibrosis (CF) have come to forefront. Increased arterial stiffness is a marker increased risk. The aim this study was compare both pulse wave velocity (PWV) and augmentation index (Aix) measurements children with CF them healthy controls. We hypothesized that had stiffness, although traditional risk factors for CVD were not observed. Forty‐four patients age sex‐matched 30 controls included study....
Abstract Background A better understanding of cystic fibrosis transmembrane conductance regulator biology has led to the development modulator drugs such as ivacaftor, lumacaftor‐ivacaftor, tezacaftor‐ivacaftor, and elexacaftor‐tezacaftor‐ivacaftor. This cross‐sectional study evaluated (CF) patients eligible for drugs. Methods Data age genetic mutations from Cystic Fibrosis Registry Turkey collected in 2018 were used find out number who are therapy. Results Of registered 1488 CF patients,...
Dynamic hyperinflation (DH) is a major contributor to exercise intolerance in patients with obstructive lung diseases. However, it has not been investigated children bronchiectasis (BE). We aimed investigate dynamic ventilatory responses and their influence on functional capacity BE.Forty BE (mean forced expiratory volume 1 s [FEV1 ] = 78 ± 19%pred) were included. Six-minute walk test (6MWT) was conducted using Spiropalm 6MWT® for evaluating including inspiratory (IC), minute ventilation...
Many surveys worldwide have consistently demonstrated a low level of asthma control and under-utilization preventive drugs. However, these studies been frequently criticized for using population-based samples, which include many patients with no or irregular follow-ups. Our aim, in this study, was to define the extent drug utilization, levels, their determinants among children attending pediatric centers Turkey. Asthmatic (age range: 6-18 yr) at least 1-yr follow-up seen 12 outpatient...
Abstract Bronchial asthma is the most common chronic respiratory illness in childhood. It characterized by paroxysmal bronchospastic periods. There are many studies giving reasons to explain bronchospasm One of reasons, atmospheric conditions, effective creating a clinical picture asthmatic patients. In present study, correlation between conditions and symptoms children was investigated using peak expiratory flow rate (PEFR) as function test. Twenty‐one with bronchial were monitored study....
Background Oral immunotherapy for cow’s milk allergy is an effective treatment option because of its ability to increase the threshold clinical reactions. Aims To present our experience oral in pediatric outpatient clinic, and evaluate long-term efficacy risk factors adverse reactions during immunotherapy. Study design Single-center retrospective cohort study. Methods Forty-two patients with Immunoglobulin-E-mediated who complied protocol were evaluated this The consisted a rapid escalation...