Alison K. Klika

ORCID: 0000-0003-2755-0742
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About
Contact & Profiles
Research Areas
  • Total Knee Arthroplasty Outcomes
  • Orthopaedic implants and arthroplasty
  • Orthopedic Infections and Treatments
  • Hip and Femur Fractures
  • Hip disorders and treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Shoulder Injury and Treatment
  • Surgical site infection prevention
  • Knee injuries and reconstruction techniques
  • Venous Thromboembolism Diagnosis and Management
  • Blood transfusion and management
  • Surgical Sutures and Adhesives
  • Health Systems, Economic Evaluations, Quality of Life
  • Musculoskeletal synovial abnormalities and treatments
  • Osteoarthritis Treatment and Mechanisms
  • Opioid Use Disorder Treatment
  • Diversity and Career in Medicine
  • Lower Extremity Biomechanics and Pathologies
  • Anesthesia and Pain Management
  • Bacterial biofilms and quorum sensing
  • Bone and Joint Diseases
  • Healthcare Policy and Management
  • Atrial Fibrillation Management and Outcomes
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Reconstructive Surgery and Microvascular Techniques

Cleveland Clinic
2016-2025

Health Outcomes Solutions (United States)
2025

Cleveland Clinic Florida
2013-2025

Cleveland Clinic Lerner College of Medicine
2024

Case Western Reserve University
2021-2024

Orthopaedic Research Society
2021-2022

Stryker (United States)
2013-2022

Creative Commons
2021

Zimmer (Switzerland)
2021

Orthopaedic Research
2013-2021

Background: The large-scale utilization of allogenic blood transfusion and its associated outcomes have been described in critically ill patients those undergoing high-risk cardiac surgery but not elective total hip arthroplasty. objective this study was to determine the trends primary arthroplasty United States from 2000 2009. Methods: An observational cohort 2,087,423 who underwent 2009 identified Nationwide Inpatient Sample. International Classification Diseases, Ninth Revision, Clinical...

10.2106/jbjs.m.00825 article EN Journal of Bone and Joint Surgery 2014-09-17

Geriatric patients experience more adverse events owing to early complications after TKA or THA related preexisting comorbidities. However, associations between patient and surgery variables, including age, BMI, comorbidities with are unclear. Knowing these relationships is necessary for developing risk stratification, defining contraindications, predicting outcomes.We wished establish quantify the among comorbidities, type of anesthesia outcomes longer length stay, disposition an extended...

10.1007/s11999-011-1804-3 article EN Clinical Orthopaedics and Related Research 2011-02-22

Objectives The diagnosis of periprosthetic joint infection (PJI) is difficult and requires a battery tests clinical findings. purpose this review to summarize all current evidence for common new serum biomarkers utilized in the PJI. Methods We searched two literature databases, using terms that encompass hip knee arthroplasty procedures, as well PJI statistical reflecting diagnostic parameters. findings are summarized narrative review. Results Erythrocyte sedimentation rate (ESR) C-reactive...

10.1302/2046-3758.71.bjr-2017-0323 article EN cc-by-nc-nd Bone and Joint Research 2018-01-01

Background: The clinical benefit of chronic suppression with oral antibiotics as a salvage treatment for periprosthetic joint infection is unclear. purpose this study was to compare infection-free prosthetic survival rates between patients who received and those did not following irrigation debridement polyethylene exchange or two-stage revision infection. Methods: We reviewed the records on all procedures revisions performed at our institution from 1996 2010 hip knee Of 625 treated total...

10.2106/jbjs.n.00999 article EN Journal of Bone and Joint Surgery 2015-08-01

Continuous wound drainage after arthroplasty can lead to the development of a periprosthetic joint infection. Closed incisional negative pressure therapy (ciNPWT) has been reported help alleviate and other complications. The purpose this prospective randomized controlled trial is compare use ciNPWT with our standard care dressing in revision patients who were at high risk develop complications.A total 160 undergoing elective prospectively receive either or silver-impregnated occlusive...

10.1016/j.arth.2018.11.017 article EN cc-by-nc-nd The Journal of Arthroplasty 2018-11-16

Obesity is a well-established risk factor for total joint arthroplasty (TJA) and number of complications including prosthetic infection. The annual changes in the prevalence obesity among primary, revision, infected TJA has not been studied at national level. Given higher costs TJA, it important to understand association with trends revision TJA.(1) Is increasing patients undergoing THA/TKA? (2) (3) THA/TKA?Annual volumes THA TKA from 1998 2011 were obtained Nationwide Inpatient Sample....

10.1007/s11999-016-5222-4 article EN Clinical Orthopaedics and Related Research 2017-01-04

The purpose of this study was to investigate the cost-effectiveness robotic-assisted total knee arthroplasty (TKA) versus conventional manual TKA in patients with osteoarthritis.A Markov model simulated lifetime outcomes at average age 60 years. Costs included a preoperative CT scan and costs for acquisition use robotic equipment (average $706,250). We used three institutional case volumes generate per-case costs: low volume (10 cases, $71,025 per case), mid (100 $7,463 high (200 $3,931...

10.5435/jaaos-d-21-00309 article EN Journal of the American Academy of Orthopaedic Surgeons 2022-01-13

Abstract Background Demographic factors have been implicated in THA and TKA outcome disparities. Specifically, patients’ racial backgrounds reported to influence outcomes after surgery, including length of stay, discharge disposition, inpatient readmissions. However, the United States, health-impacting socioeconomic disadvantage is sometimes associated with differences ways that can result important confounding, thereby raising question whether race-associated post-THA/TKA adverse are an...

10.1097/corr.0000000000002392 article EN Clinical Orthopaedics and Related Research 2022-09-14

Orthopaedic practices in the U.S. face a growing demand for total joint arthroplasties (TJAs), while orthopaedic workforce size has been stagnant decades. This study aimed to estimate annual TJA and surgeon supply from 2020 2050, develop an arthroplasty growth indicator (ASGI), based on arthroplasty-to-surgeon ratio (ASR), gauge nationwide trends.National Inpatient Sample Association of American Medical Colleges data were reviewed individuals who underwent primary active surgeons (2010...

10.2106/jbjs.22.00874 article EN Journal of Bone and Joint Surgery 2023-03-10

Background: With the upcoming U.S. Centers for Medicare & Medicaid Services 2027 policy mandatory reporting of patient-reported outcome measures (PROMs) total hip or knee arthroplasty (THA TKA), it is important to evaluate resources required achieve adequate PROM collection and at a clinically relevant rate follow-up. This study aimed (1) determine follow-up rates 1-year PROMs when was conducted with active methods (attempted contact by staff) passive (automated) methods, (2) factors...

10.2106/jbjs.23.00558 article EN Journal of Bone and Joint Surgery 2024-03-05

Frozen section histology is widely used to aid in the diagnosis of periprosthetic joint infection at second stage revision arthroplasty, although there are limited data regarding its utility. Moreover, no definitive method assess control time reimplantation. Because failure a two-stage can have serious consequences, it important identify cases that might fail and defer reimplantation if necessary. Thus, reliable test providing information about risk subsequent necessary.(1) At second-stage...

10.1007/s11999-015-4673-3 article EN Clinical Orthopaedics and Related Research 2015-12-21
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