- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Acute Ischemic Stroke Management
- Aortic Disease and Treatment Approaches
- Meningioma and schwannoma management
- Management of metastatic bone disease
- Elbow and Forearm Trauma Treatment
- Advanced Neuroimaging Techniques and Applications
- Aortic aneurysm repair treatments
- Glioma Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Cerebral Venous Sinus Thrombosis
- Moyamoya disease diagnosis and treatment
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury and Neurovascular Disturbances
- Bone Tumor Diagnosis and Treatments
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Pathology Studies
- Trigeminal Neuralgia and Treatments
- MRI in cancer diagnosis
- Dementia and Cognitive Impairment Research
- Neurosurgical Procedures and Complications
Université de Strasbourg
2012-2022
Centre National de la Recherche Scientifique
2022
Centre Hospitalier Annecy Genevois
2017-2021
Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie
2017-2019
Center of Immunology Pierre Fabre
2015-2019
Hôpitaux Universitaires de Strasbourg
2012-2018
Institut de Recherche contre les Cancers de l’Appareil Digestif
2018
Centre Hospitalier de l’Université de Montréal
2011-2016
Hôpital Notre-Dame
2011-2016
Centre Hospitalier Universitaire de Grenoble
2005-2014
Objectives To assess and compare cortical thickness (CTh) of patients with prodromal Dementia Lewy bodies (pro-DLB), Alzheimer's disease (pro-AD), DLB dementia (DLB-d), AD (AD-d) normal ageing. Methods Study participants(28 pro-DLB, 27 pro-AD, 31 DLB-d, 54 AD-d 33 elderly controls) underwent 3Tesla T1 3D MRI detailed clinical cognitive assessments. We used FreeSurfer analysis package to measure CTh investigate patterns thinning across groups. Results Comparison between pro-DLB pro-AD...
<h3>BACKGROUND AND PURPOSE:</h3> Braided self-expandable stents and flow diverters of uniform construction may develop zones heterogeneous porosity in vivo. Unwanted stenoses also occur at the extremities device. We studied these phenomena dedicated benchtop experiments. <h3>MATERIALS METHODS:</h3> Five braided devices decreasing were studied. To simulate discrepancies diameters between landing parent vessel aneurysm neck area, device inserted into silicone tubes various (2–3 mm), leaving...
Flow diverters (FDs) are increasingly used to treat complex intracranial aneurysms, but preclinical studies that could guide clinical applications lacking. The authors designed a modular aneurysm model in canines address this problem.Three variants of one were constructed 21 animals. Sidewall (n=5), curved sidewall and end-wall bifurcation (n=7) aneurysms treated with prototype 36-wire FDs. Four more 48-wire lower-porosity Angiographic results postimplantation at 3 months scored an ordinal...
<h3>BACKGROUND AND PURPOSE:</h3> FDs are new intracranial stents designed to occlude aneurysms while preserving flow jailed arterial branches. We tested this fundamental principle in a aneurysm model. <h3>MATERIALS METHODS:</h3> Canine lateral wall aneurysms, featuring branch located immediately opposite the aneurysm, were created 16 animals study effects on or occlusion using single HP (<i>n</i> = 4), 2 overlapping an FD 8). Two other animals, which efferent was anastomosed fundus, also...
Angiographic results are commonly used as a surrogate marker of success coiling intracranial aneurysms. Inter- and intraobserver agreement in judging angiographic remain poorly characterized. Our goal was to offer such an evaluation grading scale evaluate endovascular treatment
To be radiopaque, BAVM embolization products must contain high-atomic-number materials, which may also attenuate photon beams delivered with radiosurgery. This "shielding effect" has been invoked to explain why radiation therapy less effective for previously embolized BAVMs. evaluate the impact of material on dose, we measured and compared dose center an AVM model, before following various materials in a LINAC.Two vitro models were constructed by drilling interconnected tubular perforations...
<h3>BACKGROUND AND PURPOSE:</h3> Endovascular treatment of wide-neck bifurcation aneurysms often results in incomplete occlusion or aneurysm recurrence. The goals this study were to compare coil embolization with without the assistance self-expandable stents and examine how may influence neointima formation. <h3>MATERIALS METHODS:</h3> Wide-neck constructed 24 animals and, after 4–6 weeks, randomly allocated 1 5 groups: 1) using braided stent (<i>n</i> = 5); 2) 2 a Y configuration 3) 6); 4)...
<h3>BACKGROUND AND PURPOSE:</h3> FDs are the latest, most promising tool to treat giant and complex aneurysms. Currently available experimental aneurysm models do not reproduce potential clinical difficulties of treating these lesions with FDs. <h3>MATERIALS METHODS:</h3> Six large or canine fusiform aneurysms were created on distal carotid arteries 4 animals. Four had multiple arterial branches originating from aneurysm; 2 other all clipped at time construction. Aneurysms treated...
To retrospectively evaluate the suitability of MRgHIFU for osteoid osteomas (OOs) and bone metastases in patients who underwent minimally-invasive percutaneous thermal ablation.One hundred sixty-seven lesions (115 52 OOs) treated percutaneously between October 2014 June 2017 were analyzed. Tumors located spine or sacrum (54), pelvis (43), limbs (50), ribs (17) sternum (3). Tumor volume, matrix, anatomical environment need protection surrounding structures consolidation assessed. Cases...
The objectives of our study were to evaluate the incidence muscular injury after cryoablation bone and soft-tissue tumors, relate MRI findings size intramuscular ice ball, determine clinical significance postcryotherapy myositis.Between January 2010 October 2012, 24 lesions (16 pelvic lesions, three shoulder five paravertebral lesions) in 21 patients treated by imaging-guided percutaneous followed up with retrospectively analyzed. Muscular hyperintensity on T2 STIR images was graded as...
Magnetic Resonance (MR) Imaging-guided High Intensity focused Ultrasound (MRgHIFU) is a non-invasive, non-ionizing thermal ablation therapy that particularly interesting for the palliative or curative treatment of musculoskeletal tumors. We introduce new modular MRgHIFU device allows ultrasound transducer to be positioned precisely and interactively over body part treated. A flexible, MR-compatible supporting structure free positioning under MRI/optical fusion imaging guidance. The same can...
To understand why the false channel (FC) remains patent after surgery of type A acute aortic dissection (TAAAD).Postoperative contrast-enhanced computed tomography scans 129 patients operated for TAAAD were analyzed, and a color-Doppler ultrasound examination (CDUS) supra-aortic vessels (SAVs) was performed in 12 patients.The FC remained 107 (82.9%) patients. The entry site situated near distal anastomosis 43 (40.2%) far from it 44 (41.1%) In 10 (9.35%) patients, an observed only SAVs. no...
Objective: To identify petrous internal carotid bleeding aneurysm as a complication of gasserian ganglion thermocoagulation. Patients: A single case presenting with epistaxis and otorrhagia 1 month after thermocoagulation in the treatment refractory trigeminal neuralgia. Intervention(s): Gasserian thermocoagulation, computed tomographic scan, angiocomputed scan revealing ruptured embolization. Main Outcome Measure(s): Radiologic diagnosis vascular injury Results: identification artery cause...
A 32-year-old immunocompetent female patient, 8 months pregnant, underwent three complex partial seizures beginning with visual hallucinations and secondarily generalized. She had been in good health until then. The pregnancy was normal no high blood pressure noted. Clinical examination revealed a left nystagmus, right sensory hemibody deficiency pyramidal syndrome. MRI showed an isolated intraparenchymal lesion the parieto-occipital region enhancement of lateral ventricle floor (Fig. 1a,b)....