- Traumatic Brain Injury and Neurovascular Disturbances
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Trauma and Emergency Care Studies
- Neurosurgical Procedures and Complications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sepsis Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Thermal Regulation in Medicine
- Intracranial Aneurysms: Treatment and Complications
- Disaster Response and Management
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac, Anesthesia and Surgical Outcomes
- Nosocomial Infections in ICU
- Venous Thromboembolism Diagnosis and Management
- Neonatal Respiratory Health Research
- Spinal Fractures and Fixation Techniques
- Tracheal and airway disorders
- Blood transfusion and management
- Trauma Management and Diagnosis
- Takotsubo Cardiomyopathy and Associated Phenomena
- Palliative Care and End-of-Life Issues
- Emergency and Acute Care Studies
Hôpital d'Instruction des Armées Sainte-Anne
2015-2025
Grenoble Institute of Neurosciences
2023
Inserm
2023
Centre Hospitalier Universitaire de Grenoble
2023
Hôpital Raymond-Poincaré
2021-2022
Université de Reims Champagne-Ardenne
2021
Centre Hospitalier Universitaire de Reims
2021
Costruzioni Apparecchiature Elettroniche Nucleari (Italy)
2021
Service de Santé des Armées
2020
Intensive Care Society
2016-2020
Medication waste is a contributor to the healthcare environmental footprint and impacts ecosystems. Data on medication in intensive care unit (ICU) are scarce, therefore essential develop new sustainable strategies. The GAME-OVER French multicenter prospective observational study was conducted from November 2022 March 2023, over 24-h period of choice, at discretion each participating center. Adult ICUs were enrolled voluntary basis hospitalized patients who did not express opposition...
OBJECTIVE Blunt cerebrovascular injuries (BCVIs) affect approximately 1% of patients with blunt trauma. An antithrombotic or anticoagulation therapy is recommended to prevent the occurrence recurrence neurovascular events. This treatment has be carefully considered after severe traumatic brain injury (TBI), due risk intracranial hemorrhage expansion. Thus, physician in charge patient confronted a hemorrhagic and ischemic risk. The main objective this study was determine incidence BCVI TBI....
BACKGROUND Early transfusion of high ratio fresh frozen plasma (FFP) and red blood cells (RBC) is associated with mortality reduction. However, time to reach limited by the need thaw FFP. French lyophilized (FLYP) used army available in military teaching hospital does not be thawed immediately available. We hypothesize that use FLYP may reduce a plasma/RBC 1:1. METHODS A retrospective study performed Level 1 trauma center between January 2012 December 2015. Severe patients who received 2 U...
ABSTRACT Introduction To date, there is no evidence concerning the emergency surgical management of severe trauma patients (STP) with traumatic brain injury (STBI) presenting a life-threatening intracranial hematoma and concomitant extra-cranial noncompressible active bleeding. Current guidelines recommend stopping bleeding first. Nevertheless, long-term outcome STP STBI mainly depends from lesions. Thus, we propose combined damage-control strategy aiming to reduce time spent hypertension...
ICUs have had to deal with a large number of patients acute respiratory distress syndrome COVID-19, significant whom received prone ventilation, which is substantial consumer care time. The selection that we ventilate in position seems interesting. We evaluate the correlation between percentage collapsed dependent lung areas supine position, monitoring by electrical impedance tomography and oxygenation response (change Pao2/Fio2 ratio) position.An observational prospective study.From October...
Microvesicles (MVs) have previously been shown to exert profibrinolytic capacity, which is increased in patients with septic shock (SS) a favorable outcome. We, therefore, hypothesized that the plasmin generation capacity (PGC) could confer MVs protective effect supported by their lyse thrombus, and we investigated mechanisms involved. Using an MV-PGC kinetic assay, ELISA, flow cytometry, found granulocyte (Gran-MVs) from SS display heterogeneous PGC profile driven uPA (urokinase)/uPAR...
Deviation from guidelines is frequent in emergency situations, and this may lead to increased mortality. Probably because of time constraints, 55% the greatest reported compliance rate severe trauma patients. This study aimed identify among all available recommendations a reasonable bundle items that should be followed optimize outcome hemorrhagic shocks (HSs) traumatic brain injuries (TBIs).We first estimated with French European using data TraumaBase registry. Then, we used machine...