A5031896113- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Voice and Speech Disorders
- Respiratory Support and Mechanisms
- Esophageal and GI Pathology
- Congenital Diaphragmatic Hernia Studies
- Child Nutrition and Feeding Issues
- Gastroesophageal reflux and treatments
- Airway Management and Intubation Techniques
- Infant Health and Development
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Neonatal Respiratory Health Research
- Transcranial Magnetic Stimulation Studies
- Cardiovascular and Diving-Related Complications
- Eosinophilic Esophagitis
- Spinal Cord Injury Research
- Stuttering Research and Treatment
- Diet and metabolism studies
- Cerebral Palsy and Movement Disorders
- Clinical Nutrition and Gastroenterology
- Neurological disorders and treatments
- Cardiac Arrest and Resuscitation
- Helicobacter pylori-related gastroenterology studies
Université de Rouen Normandie
2016-2025
Normandie Université
2017-2025
Hôpital Charles-Nicolle
2001-2018
Centre Hospitalier Universitaire de Rouen
2006-2017
Institute for Research and Innovation in Biomedicine
2013-2017
Institut Régional de Médecine Physique et de Réadaptation
2014-2017
Institute for Biomedicine
2017
Inserm
2010-2013
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2002-2005
Université Laval
2002-2005
Combined esophageal pH-impedance monitoring allows detection of nearly all gastroesophageal reflux episodes, acid as well nonacid. However, the role nonacid in pathogenesis symptoms is poorly known. The aim this study was to evaluate diagnostic yield technique patients with suspected while on or off PPI therapy.The recordings 150 recruited at seven academic centers possibly related were analyzed. Reflux events detected visually using impedance (Sandhill, CO) and then characterized by pHmetry...
Post-stroke dysphagia (PSD) is present in more than 50% of acute stroke patients, increases the risk complications, particular aspiration pneumonia, malnutrition and dehydration, linked to poor outcome mortality. The aim this guideline assist all members multidisciplinary team their management patients with PSD. These guidelines were developed based on European Stroke Organisation (ESO) standard operating procedure followed Grading Recommendations, Assessment, Development Evaluation (GRADE)...
Summary Background : Impedance‐pH monitoring is the most sensitive method for detection and characterization of gastro‐oesophageal reflux episodes. Normal values from European subjects are lacking. Aim To build a database patterns French Belgian healthy subjects. Methods Seventy‐two (35 men, mean age 35 years, 18–72) underwent 24‐h ambulatory impedance‐pH studies. Gastro‐oesophageal episodes were detected using impedance characterized by pH as acid, weakly acidic, or alkaline. Analysis was...
The integrity of the central efferent motor pathways to diaphragm can be assessed by using transcranial magnetic stimulation measure latency corresponding evoked potentials with surface electrodes. Because does not activate alone, signal contamination is a potential problem. To evaluate this issue, diaphragmatic motor-evoked latencies were compared recorded from needle in 9 healthy volunteers. Surface muscles likely contaminate signals (serratus anterior, pectoralis major, and tranversus...
Summary Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis ( ALS ). Our aim was to determine whether oropharyngeal dysphagia impacted quality life Q o L ) patients with . Thirty consecutive were recruited (31–82 years, 18 men). Swallowing function evaluated using a standardised videofluoroscopic barium swallow. All completed specific questionnaire on SWAL ‐ immediately after videofluoroscopy. The results outcome severity scale separated 14 and...
Phrenic nerve stimulation, electrical (ES) or from cervical magnetic stimulation (CMS), allows one to assess the diaphragm contractile properties and conduction time of phrenic (PNCT) through recording an electromyographic response, traditionally by using surface electrodes. Because coactivation extradiaphragmatic muscles, signal contamination can jeopardize determination PNCTs. To address this, we compared PNCTs with ES CMS needle electrodes in five subjects (10 nerves). At a modified site,...
To investigate compliance with transanal irrigation (TAI) one year after a training session and to identify predictive factors for compliance.The of hundred eight patients [87 women 21 men; median age 55 years (range 18-83)] suffering from constipation or fecal incontinence (FI) was retrospectively assessed. The were trained in TAI over four-year period at single institution. They classified as adopters if they continued using least beginning the treatment non-adopters stopped. Predictive...
It is unknown whether changes in corticomotor excitability follow exercise healthy humans. We hypothesized that a fall the diaphragm and quadriceps motor-evoked potential (MEP) amplitude elicited by transcranial magnetic stimulation of motor cortex would occur after an incremental task. In 11 subjects, we measured transdiaphragmatic pressure isometric tension response to supramaximal peripheral nerve stimulation. MEPs were recorded from these muscles After baseline measurements, subjects...
Spinal cord injury (SCI) induces a permanent disability in patients. To this day no curative treatment can be proposed to restore lost functions. Therefore, extensive experimental studies have been conducted induce recovery after SCI. One of the most promising therapies is based on use olfactory ensheathing cells (OECs). OECs obtained from either bulbs (OB-OECs) or mucosa (OM-OECs), involving less invasive approach for autotransplantation. However vast majority transplantations focusing...
Our study aimed to investigate swallowing coordination by analyzing ventilatory patterns during of solids and liquids food intakes. Twenty-one patients with severe very stable COPD (GOLD III IV) underwent ventilation recordings while performing standardized tasks. The results revealed that the expiratory-expiratory (EE) pattern was predominant, accounting for 80 % swallows, no significant differences between solid liquid swallows. Non-EE occurred in an average 20.68 swallows per patient....
Background: A study was undertaken to examine the expiratory flow response a negative pressure (NEP) applied at airway in patients with no abnormalities of intrathoracic but suffering from obstructive sleep apnoea syndrome (OSAS). Methods: Nineteen OSAS normal spirometric values were studied. NEP –5 cm H2O and –10 mouth when sitting supine. Results: Thirteen exhibited limitation supine (group 1). Of these, three also had position. The remaining six 2) limitation. Patients groups 1 2 similar...