Clara Maria Gonçalves de Faria

ORCID: 0000-0003-2767-7639
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About
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Research Areas
  • Photodynamic Therapy Research Studies
  • Laser Applications in Dentistry and Medicine
  • Nanoplatforms for cancer theranostics
  • Photoacoustic and Ultrasonic Imaging
  • Bee Products Chemical Analysis
  • Dermatologic Treatments and Research
  • Luminescence Properties of Advanced Materials
  • Laser-Ablation Synthesis of Nanoparticles
  • Medical and Biological Ozone Research
  • Polymer composites and self-healing
  • Advanced Radiotherapy Techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Essential Oils and Antimicrobial Activity
  • Lignin and Wood Chemistry
  • biodegradable polymer synthesis and properties
  • Long-Term Effects of COVID-19
  • Cancer, Hypoxia, and Metabolism
  • Nanoparticles: synthesis and applications
  • Diamond and Carbon-based Materials Research
  • Boron Compounds in Chemistry
  • Oral health in cancer treatment
  • Skin Protection and Aging
  • Radiation Therapy and Dosimetry
  • Advanced Polymer Synthesis and Characterization
  • Lanthanide and Transition Metal Complexes

Universidade de São Paulo
2016-2023

University of Padua
2023

Universidade Federal de São Carlos
2020-2021

Abstract New multifunctional theranostic vectors allow the expansion of cancer therapeutic approaches toward scarcely investigated fields. One example is combination boron neutron capture therapy (BNCT) and X‐ray radiotherapy (XRT) for treating normal XRT‐resistant hypoxic tumor regions reduce recurrence. Of great relevance BNCT also support viable, rapid, safe, reliable techniques localization quantification radiosensitizers in tissues. To address these challenges, polymer‐coated Au‐B...

10.1002/adfm.202303366 article EN cc-by-nc Advanced Functional Materials 2023-06-20

Photobiomodulation therapy (PBMT) uses light to stimulate cells. The molecular basis of the effects PBMT is being unveiled, but it stated that cytochrome-c oxidase enzyme in mitochondria, a photon acceptor PBMT, contributes an increase ATP production and modulates reduction oxidation electron carriers NADH FAD. Since its are not fully understood, used on tumors. Thus, interesting investigate if correlate mitochondrial metabolism so, how could be linked optical redox ratio (ORR), defined as...

10.1364/boe.421302 article EN cc-by Biomedical Optics Express 2021-04-29

One important limitation of topical photodynamic therapy (PDT) is the limited tissue penetration precursors. Microneedles (MNs) are minimally invasive devices used to promote intradermal drug delivery. Dissolving MNs contain drug-associated polymer blends, dissolving after insertion into skin, allowing release. This study comprises development and characterization a pyramidal model (500 μm) prepared with 5% wt/wt aminolevulinic acid 20% Gantrez AN-139 in aqueous blend. Protoporphyrin IX...

10.1002/jbio.202000128 article EN Journal of Biophotonics 2020-09-27

Nanomedicine relies on the exploitation of nanoscale constructs for therapeutic and diagnostic functions. Gold gold-iron alloy nanoparticles (NPs) are two examples nanomaterials with favorable features use in nanomedicine. While gold NPs have been studied extensively last decades, they not biodegradable. Nonetheless, biodegradation was recently observed alloys iron obtained using laser ablation liquid (LAL). Hence, there is a significant interest study biological effects nanoparticles,...

10.3390/nano13233044 article EN cc-by Nanomaterials 2023-11-29

Herein we describe the design of natural curcumin ester and ether derivatives their application as potential bioplasticizers, to prepare photosensitive phthalate-free PVC-based materials. The preparation films incorporating several loadings newly synthesized along with standard solid-state characterization is also described. Remarkably, plasticizing effect in PVC material was found be similar that observed previous PVC–phthalate Finally, studies applying these new materials photoinactivation...

10.3390/molecules28052209 article EN cc-by Molecules 2023-02-27

Abstract The post-COVID-19 condition or ‘long COVID’ is a clinical and scientific challenge for society. In this regard, patients after COVID-19 recovery show vast range of sequels including muscular, articular lesions, neurological, dermatological, pulmonary issues. These consequences are issues in the present future. case, rehabilitation therapies based on photobiomodulation combined arise as excellent tools to solve it. Herein, we describe discuss perspectives use light-based such...

10.1088/1612-202x/ac52f5 article EN Laser Physics Letters 2022-03-09

Photobiomodulation (PBM) uses light to stimulate cells. The molecular basis of the effects PBM is being unveiled, but it stated that cytochrome-c oxidase enzyme in mitochondria, a photon acceptor PBM, contributes an increase ATP production and modulates reduction oxidation electron carriers NADH FAD. As can cells, not used on tumors. Thus, interesting investigate if its correlate mitochondrial metabolism so, how could be linked optical redox ratio (ORR). To end, fibroblasts oral cancer cells...

10.1101/2020.09.07.285908 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2020-09-07

Experimental Photodynamic Therapy (PDT), either in vivo or vitro, is normally carried out under distinct conditions making it difficult to compare results order propose the best combination for optimized outcomes. In this work, a threshold distribution model was used investigate PDT response vitro. It known that different types of cells present distinguished resistance treatment, which can be due several factors. The obtained from differentiation dose-response curves, discussion by authors....

10.1117/12.2250640 article EN 2017-04-19
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