A5019707771- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Livestock and Poultry Management
- Animal Nutrition and Physiology
- Sports injuries and prevention
- Lower Extremity Biomechanics and Pathologies
- Shoulder Injury and Treatment
- Retinoids in leukemia and cellular processes
- Shoulder and Clavicle Injuries
- Estrogen and related hormone effects
- RNA and protein synthesis mechanisms
- Biochemical Analysis and Sensing Techniques
- Orthopedic Surgery and Rehabilitation
- Nuclear Receptors and Signaling
- Neurological diseases and metabolism
- Children's Physical and Motor Development
- Genomics and Phylogenetic Studies
- Natural Compound Pharmacology Studies
- interferon and immune responses
- Ubiquitin and proteasome pathways
- Biological Activity of Diterpenoids and Biflavonoids
- Bioactive Compounds and Antitumor Agents
- Foot and Ankle Surgery
- Agricultural Systems and Practices
- Phytochemistry and Biological Activities
Shanghai Sixth People's Hospital
2020-2025
Shanghai Jiao Tong University
2017-2025
Nantong University
2024
Foshan Maternity and Child Health Care Hospital
2018-2023
Southern Medical University
2023
Beijing Sport University
2022
Jiaying University
2012-2020
University of Science and Technology of China
2019
Guangdong Ocean University
2018
Tongren Hospital
2017
Sports levels, baseline patient-reported outcome measures (PROMs), and surgical procedures are correlated with the outcomes of anterior cruciate ligament reconstruction (ACLR). Machine learning may be superior to conventional statistical methods in making repeatable accurate predictions.To identify best-performing machine models for predicting objective subjective clinical ACLR determine most important predictors.Case-control study; Level evidence, 3.A total 432 patients who underwent...
Context : To further improve rehabilitation programs while preventing overstretching the anterior cruciate ligament (ACL), a thorough understanding of knee kinematics and ACL length change during closed kinetic chain open (OKC) exercises is essential. The measurement graft relates to changes in strain experienced by different types rather than simple physical length. Objective This study aimed determine effects OKC on tibiofemoral following double-bundle reconstruction. Design Cohort...
It is a big challenge to develop polyethylene terephthalate (PET) artificial ligament with excellent osteogenetic activity enhance graft-bone integration for reconstruction. Herein, we evaluated the effect of biomineralization (BM) and electrodeposition (ED) method depositing calcium-phosphate (CaP) on PET in vitro vivo. Scanning electron microscopy energy-dispersive X-Ray spectrometer mapping analysis revealed that ED-CaP had more uniform particles element distribution (Ca, P O),...
Abstract Background Yellow-feathered chickens (YFCs) have a long history in China. They are well-known for the nutritional and commercial importance attributable to their yellow color phenotype. Currently, there is huge paucity knowledge of genetic determinants responsible phenotypic biochemical properties these iconic chickens. This study aimed uncover structure molecular underpinnings YFCs trademark coloration. Results The whole-genomes 100 from 10 major traditional breeds Huaibei...
Background: Osteoporosis increases the revision rate of rotator cuff repair (RCR). Weak fixation might not be only cause high RCR failure rates. The biological mechanism associated with tendon-to-bone healing after in osteoporosis should investigated. Hypothesis: (1) would impair through osteoclastic activity at repaired interface. (2) Risedronate promote by reducing Study Design: Controlled laboratory study. Methods: A total 84 female Sprague Dawley rats were randomly treated using...
Retinoic acid receptors (RAR; alpha, beta, and gamma), members of the nuclear receptor superfamily, mediate pleiotropic effects vitamin A metabolite retinoic (RA) derivatives (retinoids) in normal cancer cells. Abnormal expression function RARs are often involved growth development cancer. However, underlying molecular mechanisms remain largely elusive. Here, we report that levels RARgamma were significantly elevated tumor tissues from a majority human hepatocellular carcinoma (HCC) HCC cell...
Background: The purpose of this trial was to determine whether anterior cruciate ligament reconstruction (ACLR) with anterolateral structure augmentation (ALSA) would result in better clinical outcomes patients a high risk failure. Methods: From February 2017 June 2018, 120 young, active adults chronic injury and failure were randomized. followed for >2 years, 5 being lost follow-up 1 withdrawn from the study. Clinical characteristics, operative findings, postoperative analyzed. Results:...
Six new compounds, pruniflorones M−R (1−6), together with 19 known compounds (7−25) were isolated from the stems of Cratoxylum formosum ssp. pruniflorum. The structures established on basis extensive spectroscopic data interpretation. In addition, their RXRα transcriptional activities evaluated using an in vitro assay.
A truncated version of retinoid X receptor-α, tRXR-α, promotes cancer cell survival by activating the phosphoinositide 3-kinase (PI3K)/AKT pathway. However, targeting tRXR-α-mediated pathway for treatment remains to be explored. We report here our identification a new natural product molecule, CF31, xanthone isolated from Cratoxylum formosum ssp. pruniflorum, and biologic evaluation its regulation PI3K/AKT CF31 binds RXR-α binding results in inhibition transactivation. Through mutational...
Background: Anterolateral structure augmentation (ALSA) has been applied to prevent residual rotatory instability and lower clinical failure rates after anterior cruciate ligament (ACL) reconstruction (ACLR); however, the effect of combined ALSA on maturity ACL grafts remains unknown. Purpose: To evaluate graft patient–reported outcomes in patients who underwent double–bundle ACLR with or without ALSA. Study Design: Cohort study; Level evidence, 3. Methods: A total 92 between January 2016...
Background Endometriosis (EMs), a common gynecological disorder, adversely affects the quality of life females. The pathogenesis EMs has not been elucidated and diagnostic methods for have limitations. This study aimed to identify potential molecular biomarkers diagnosis treatment EMs. Methods Differential gene expression (DEG) functional enrichment analyses were performed using R language. WGCNA, Random Forest, SVM-REF LASSO used core immune genes. CIBERSORT algorithm was then analyse...
Highly diversified in morphology and structure, feathers have evolved into various forms. Frizzle feathers, which result from a developmental defect of the feather, are observed several domestic chicken breeds. The frizzle phenotype is consistent with incomplete dominance major gene, but molecular mechanisms that underlie this remain obscure. Kirin, Chinese indigenous breed originated Guangdong province, famous for its feathers. KRT75 gene considered as dominant responsible trait breeds, not...
Background: Medial patellofemoral ligament (MPFL) reconstruction is one of the main treatments for lateral patellar translation. Based on intraoperative true radiographs, accepted methods femoral MPFL tunnel location are potentially inaccurate. Direct assessment anatomic characteristics during surgery through palpation landmarks involving saddle sulcus might help eliminate malposition. Hypothesis: The a reliable osseous landmark where attaches placement. Study Design: Descriptive laboratory...
The purposes of the present study were (1) to measure tibial tuberosity-trochlear groove distance and its components with knee in extension, (2) determine their diagnostic performance distinguishing between patients without episodic patellar dislocation, (3) investigate relationship each component total distance.We retrospectively reviewed computed tomography (CT) images joint a group dislocation control subjects who treated for another type disorder our institution 2015 2021. Tibial...