Miloš Nikolić

ORCID: 0000-0003-2816-3218
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Research Areas
  • Plant Physiology and Cultivation Studies
  • Essential Oils and Antimicrobial Activity
  • Berry genetics and cultivation research
  • Horticultural and Viticultural Research
  • Phytochemistry and Biological Activities
  • Fungal Biology and Applications
  • Bacterial biofilms and quorum sensing
  • Growth and nutrition in plants
  • Plant Pathogens and Fungal Diseases
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis
  • Plant Reproductive Biology
  • Antimicrobial Peptides and Activities
  • Postharvest Quality and Shelf Life Management
  • Plant chemical constituents analysis
  • Phytochemistry and Bioactivity Studies
  • Polysaccharides and Plant Cell Walls
  • Botany and Plant Ecology Studies
  • Piperaceae Chemical and Biological Studies
  • Insect Pest Control Strategies
  • Antifungal resistance and susceptibility
  • Marine Sponges and Natural Products
  • Antimicrobial agents and applications
  • Ethnobotanical and Medicinal Plants Studies
  • Eicosanoids and Hypertension Pharmacology

University of Belgrade
2011-2023

University of Kragujevac
2022-2023

Univerzitet Union Nikola Tesla
2019

Institute for Biological Research “Siniša Stanković”
2011-2016

Oregon State University
2016

Institute for Biological Sciences
2011-2015

University of Nis
2011-2012

Culture Resource
2011

Institute of Biophysics
2011

AbstractThe antiradical activity of phytol was evaluated by electron paramagnetic resonance towards hydroxyl radical (√OH), superoxide anion (), methoxy (√CH2OH), carbon-dioxide as well nitric-oxide (√NO) and 2,2-diphenyl-1-picrylhydrazyl (√DPPH) radical. It reduced the production all tested radicals showing more promising against , √CH2OH √DPPH (56%, 50% 48%, respectively) in comparison with √NO, √OH (38%, 23% 15%, respectively). The antimicrobial microdilution method eight bacterial fungal...

10.1080/14786419.2013.869692 article EN Natural Product Research 2014-01-14

Anti-quorum sensing activity of the diterpene phytol was evaluated in vitro for first time. This compound (at three sub-MIC concentrations – 0.5, 0.25 and 0.125 MIC, respectively) reduced formation Pseudomonas aeruginosa PAO1 biofilm range 74.00–84.33% exhibiting higher than both positive controls used, streptomycin ampicillin. Phytol (0.5 MIC) also effectively P. twitching flagella motility. Indeed, bacteria treated were incapable producing a zone had almost round, smooth regular colony...

10.1080/14786419.2014.945088 article EN Natural Product Research 2014-08-07

This work was focused on in vitro evaluation of anti-biofilm and anti-quorum sensing effects four selected flavonoid compounds /(+)-catechin, caffeic acid, quercetin morin/ using the strain Pseudomonas aeruginosa PAO1. At a concentration 0.5 MIC only compound found to potently reduce both P. biofilm formation (95%) its twitching motility. The chemical scaffold quercetin, common dietary polyphenol, may actually inspire development novel more effective medicinal agents targeting aeruginosa,...

10.2174/1389201016666150505121951 article EN Current Pharmaceutical Biotechnology 2015-06-05

This work covers the chemical composition and antimicrobial activities of essential oils isolated from Satureja thymbra Thymbra spicata analyzed using GC/MS. The main components S. oil were thymol (33.8 %), ?-terpinene (30.8 %) p-cymene (11.8 %). in T. carvacrol (74.5 (11.2 their components, carvacrol, assayed by applying microdilution method for antibacterial antifungal activity against food poisoning, plant, animal human pathogenic microorganisms. showed highest activity.

10.2298/abs1102457m article EN cc-by Archives of Biological Sciences 2011-01-01

The edible mushroom Agaricus blazei Murill is known to induce protective immunomodulatory action against a variety of infectious diseases. In the present study we report potential anti-quorum sensing properties A. hot water extract. Quorum (QS) plays an important role in virulence, biofilm formation and survival many pathogenic bacteria, including Gram negative Pseudomonas aeruginosa, considered as novel promising target for anti-infectious agents. this study, effect sub-MICs extract on QS...

10.3390/molecules19044189 article EN cc-by Molecules 2014-04-03

<italic>Agaricus bisporus</italic> is a cultivated mushroom; <italic>A. bitorquis</italic>, campestris</italic> and macrosporus</italic> are edible mushrooms growing wild in nature.

10.1039/c4fo01135j article EN Food & Function 2015-01-01

Abstract Objectives The chemical composition, antimicrobial and synergistic effect, cytotoxic activity of Citrus limon (lemon), Piper nigrum (green pepper) Melaleuca alternifoila (tea tree) essential oils (EOs) were investigated. Methods Chemical analyses tested by GC-FID GC-MS spectroscopy. assay was conducted using microdilution method against several oral bacteria Candida spp. originating from the humans with disorders. evaluated checkerboard method. cytotoxicity evaluation EOs assessed...

10.1111/jphp.12792 article EN Journal of Pharmacy and Pharmacology 2017-08-17

The anti-quorum sensing activities towards the bacterium Pseudomonas aeruginosa PA01 (pyocyanin production, biofilm formation and twitching flagella motility) of two crude extracts (methanol acetone) freshwater sponge Ochridaspongia rotunda (Arndt, 1937) were evaluated in vitro for first time. Both demonstrated P. pyocyanin inhibitory activity, reducing its production 49.90% 42.44%, respectively. In addition, they both showed higher anti-biofilm activity (48.29% 53.99%, respectively) than...

10.1080/14786419.2014.934239 article EN Natural Product Research 2014-07-21

A decision-making approach based on Data Envelopment Analysis (DEA) for determining the efficient container handling processes (considering number of employed Automated Guided Vehicles (AGVs)) at a port terminal (PCT) is presented in this paper. Containers are unloaded from ship by quay cranes and transported to storage area AGVs. We defined performance measures proposed analysed effects when changing The values were collected and/or calculated simulation. Container process, with fixed...

10.1080/00207543.2016.1241445 article EN International Journal of Production Research 2016-10-06

Essential oils are well known as strong antimicrobial agents of plant origin. In spite this, the synergism essential isolated from different species is poorly investigated. The following study examines Origanum vulgare L. and Thymus vulgaris L against pathogenic bacteria, Staphylococcus aureus Salmonella typhimurium. First, antibacterial effect was tested, minimal inhibitory concentrations (MIC) both were determined using microdilution method. To test whether act synergistically, every...

10.2298/abs1302639s article EN cc-by Archives of Biological Sciences 2013-01-01

Anti-biofilm activity of three anthocyanidins (pelargonidin, cyanidin and delphinidin) was evaluated for the first time at in vitro conditions. All compounds reduced formation Pseudomonas aeruginosa PAO1 biofilm low sub-MIC (0.125 MIC) with delphinidin (c 56.25 μg/mL) being most active (43%). In comparison, ampicillin 93.75 streptomycin 21.25 (used as positive controls) were considerably less effective same (8 12%, respectively). Furthermore, 0.5 MIC 225 this anthocyanidin molecule partly...

10.1080/14786419.2016.1222386 article EN Natural Product Research 2016-08-19

This work extends in vitro screening of antimicrobial activity the sesquiterpene hydroquinone avarol, a main secondary metabolite Mediterranean sponge species Dysidea avara. The was part evaluated by microdilution method against selected bacterial and fungal strains. Additionally, included evaluation anti-quorum sensing (anti-QS) effects. At different extent avarol proven to be active all microorganisms tested (MIC 0.002-0.008 mg/mL MBC 0.004-0.016 mg/mL; MIC 0.004-0.015 MFC 0.008-0.030...

10.2174/138920101506140910152253 article EN Current Pharmaceutical Biotechnology 2014-09-10
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