Bin Sun

ORCID: 0000-0003-2816-7657
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About
Contact & Profiles
Research Areas
  • Diabetes Treatment and Management
  • Sodium Intake and Health
  • Inflammation biomarkers and pathways
  • Immune Response and Inflammation
  • Genetic Syndromes and Imprinting
  • Parathyroid Disorders and Treatments
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Autoimmune and Inflammatory Disorders Research
  • Pregnancy and preeclampsia studies
  • Blood disorders and treatments
  • Selenium in Biological Systems
  • Nutritional Studies and Diet
  • MicroRNA in disease regulation
  • Chronic Kidney Disease and Diabetes
  • Dialysis and Renal Disease Management
  • Psoriasis: Treatment and Pathogenesis
  • Signaling Pathways in Disease
  • Cytokine Signaling Pathways and Interactions
  • Neonatal and Maternal Infections
  • Cell Adhesion Molecules Research
  • Renal Diseases and Glomerulopathies
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Pediatric health and respiratory diseases
  • Systemic Lupus Erythematosus Research
  • Asthma and respiratory diseases

Jiangsu Province Hospital
2012-2024

Nanjing Medical University
2015-2024

Heilongjiang Bayi Agricultural University
2020

Hangzhou Medical College
2020

Zhejiang Provincial People's Hospital
2020

Soochow University
2020

Binzhou University
2020

Binzhou Medical University
2020

Sepsis often leads to cardiac dysfunction and inflammation. This study investigated the clinical value of microRNA-328 (miR-328) in sepsis its role inflammation caused by sepsis. The expression level miR-328 serum subjects was detected qRT-PCR. Receiver operating characteristic (ROC) curve measured diagnostic Rat model established detect left ventricular systolic pressure (LVSP), end-diastolic (LVEDP), maximal rate increase/decrease (±dp/dtmax). Myocardial injury markers troponin I (cTnI),...

10.1590/1414-431x20209501 article EN cc-by Brazilian Journal of Medical and Biological Research 2020-06-20

To evaluate whether soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) can be used as an early predictor of ventilator-associated pneumonia (VAP).Ventilated neonatal patients admitted into the neonatology department between January 2017 and 2018 were divided VAP (n = 30) non-VAP groups. Serum sTREM, procalcitonin (PCT), C-reactive protein interleukin-6 levels measured at 0, 24, 72, 120 h after initiation mechanical ventilation (MV). Correlations blood biomarker concentrations...

10.1186/s12879-020-05196-z article EN cc-by BMC Infectious Diseases 2020-07-25

Background High sodium intake and fluid overhydration are common factors of strongly associated with adverse outcomes in chronic kidney disease (CKD) patients. Yet, their effects on cardiac dysfunction remain unclear. Aims The study aimed to explore the impact salt volume overload alterations non-dialysis CKD. Methods In all, 409 patients CKD stages 1–4 (G1–G4) were enrolled. Daily (DSI) was estimated by 24-h urinary excretion. Volume status evaluated ratio extracellular water (ECW) total...

10.3389/fnut.2024.1388591 article EN cc-by Frontiers in Nutrition 2024-05-27

Objectives To explore the association of cortico-medullary difference in apparent diffusion coefficient (ΔADC) with clinicopathological parameters disease activity at time biopsy, and prognositic risk stratification IgA nephropathy (IgAN) patients.

10.1080/0886022x.2024.2441394 article EN cc-by Renal Failure 2024-12-17

Abstract The current study aimed to assess the dietary salt intake in patients with CKD Jiangsu province and investigate relationship of urinary sodium excretion blood pressure. A total 800 stages 1–4 were recruited. All enrolled asked collect complete 24‐h urine specimen. At same time, patient's demographic laboratory data recorded. mean age was 47.45 ± 15.25 years old, including 423 men 377 women. There no significant difference among different ( p = .748). This revealed that median all...

10.1111/jch.14307 article EN cc-by-nc-nd Journal of Clinical Hypertension 2021-06-15

Objective To investigate the influencing factors of hungry bone syndrome (HBS) in maintenance hemodialysis patients with secondary hyperparathyroidism (SHPT) after parathyroidectomy (PTX). Methods A retrospective study was conducted on SHPT undergoing successful autotransplantation. Clinical data and perioperative indicators selected were collected. The enrolled divided into HBS group non-HBS based whether lowest level blood calcium less than 2.0 mmol/L surgery. difference general...

10.3760/cma.j.issn.1001-7097.2019.08.002 article EN Zhonghua shenzangbing zazhi 2019-08-15

Objective To investigate the role of peptidyl arginine deiminase 4 (PAD4) in anti-β2GP1/β2GP1 complex-induced formation neutrophil extracellular trapping networks (NETs). Methods Peripheral blood neutrophils were isolated from healthy humans by density gradient centrifugation. PAD4 expression was detected Western blot after incubated with complex (100 μg/ml) for a certain period time. inhibitor Cl-amidine (10 μmol/L) used to pretreat neutrophils. Changes citrullinated histone 3...

10.3760/cma.j.cn112309-20190606-00178 article EN 2020-02-29
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