Anne-Laure Werner

ORCID: 0000-0003-2827-7653
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About
Contact & Profiles
Research Areas
  • Water Treatment and Disinfection
  • Polyamine Metabolism and Applications
  • Distributed and Parallel Computing Systems
  • Environmental Toxicology and Ecotoxicology
  • Sulfur Compounds in Biology
  • Chemical Safety and Risk Management
  • Carcinogens and Genotoxicity Assessment
  • Computational Drug Discovery Methods
  • Animal testing and alternatives
  • Effects and risks of endocrine disrupting chemicals

Stratophase (United Kingdom)
2018

The onset of the N-nitrosamine (NA) saga in 2018 was chiefly related to certain small dialkyl N-nitrosamines originating from synthesis active pharmaceutical ingredient (API). However, subsequent comprehensive assessments performed on APIs, formulated drug products, and packaging put a different type NAs limelight: diverse range complex so-called nitrosamine drug-substance-related impurities (NDSRIs). They may form due presence potentially nitrosatable secondary or tertiary amine moieties...

10.1021/acs.oprd.3c00100 article EN cc-by-nc-nd Organic Process Research & Development 2023-07-26
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