A5038199543- Sleep and related disorders
- Sleep and Wakefulness Research
- Mental Health Research Topics
- Maternal Mental Health During Pregnancy and Postpartum
- Treatment of Major Depression
- Youth Substance Use and School Attendance
- Circadian rhythm and melatonin
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Psychotherapy Techniques and Applications
- Sleep and Work-Related Fatigue
- Child and Adolescent Psychosocial and Emotional Development
- Digital Mental Health Interventions
- Obstructive Sleep Apnea Research
- Acupuncture Treatment Research Studies
- Mindfulness and Compassion Interventions
- Infant Development and Preterm Care
- Complementary and Alternative Medicine Studies
- Musculoskeletal pain and rehabilitation
- Menstrual Health and Disorders
- Child Nutrition and Feeding Issues
- COVID-19 and Mental Health
- Early Childhood Education and Development
- Psychosomatic Disorders and Their Treatments
- Schizophrenia research and treatment
- Neuroscience of respiration and sleep
Stanford University
2016-2025
Monash University
2024
Palo Alto University
2013-2023
Stanford Medicine
2002-2022
Neurosciences Institute
2019
Institute of Behavioral Sciences
2016
VA Palo Alto Health Care System
2013-2015
California Center for Sleep Disorders
2013
University of Arizona
1992-2010
University of California, San Francisco
2010
Patients with chronic forms of major depression are difficult to treat, and the relative efficacy medications psychotherapy is uncertain.
Although sexual dysfunction is common in psychiatric patients, quantification of limited by the paucity validated,user-friendly scales. Inorder to address this problem,the authors have developed Arizona Sexual Experiences Scale (ASEX), a five-item rating scale that quantifies sex drive, arousal, vaginal lubrication/penile erection, ability reach orgasm, and satisfaction from orgasm. Possible total scores range 5 30, with higher indicating more dysfunction. This study assesses internal...
Insomnia impacts the course of major depressive disorder (MDD), hinders response to treatment, and increases risk for relapse. This study is an initial evaluation adding cognitive behavioral therapy insomnia (CBTI) antidepressant medication escitalopram (EsCIT) in individuals with both disorders.A randomized, controlled, pilot a single academic medical center.30 (61% female, mean age 35 +/- 18) MDD insomnia.EsCIT 7 individual sessions CBTI or CTRL (quasi-desensitization).Depression was...
To evaluate the efficacy of mindfulness meditation for treatment chronic insomnia.Three-arm, single-site, randomized controlled trial.Academic medical center.Fifty-four adults with insomnia.Participants were to either mindfulness-based stress reduction (MBSR), therapy insomnia (MBTI), or an eight-week self-monitoring (SM) condition.Patient-reported outcome measures total wake time (TWT) from sleep diaries, pre-sleep arousal scale (PSAS), measuring a prominent waking correlate insomnia, and...
To evaluate whether depressive symptom severity leads to poorer response and perceived adherence cognitive behavioral therapy for insomnia (CBTI) examine the impact of CBTI on well-being, severity, suicidal ideation.Pre- posttreatment case replication series comparing low depression (LowDep) high (HiDep) groups (based a cutoff 14 Beck Depression Inventory [BDI]).127 men 174 women referred treatment insomnia.Seven sessions group CBTI.Improvement in energy, productivity, self-esteem, other...
Although many studies report that the therapeutic alliance predicts psychotherapy outcome, few exclude possibility this association is accounted for by 3rd variables, such as prior improvement and prognostically relevant patient characteristics. The authors treated 367 chronically depressed patients with cognitive-behavioral analysis system of (CBASP), alone or medication. Using mixed effects growth-curve analyses, they found early significantly predicted subsequent in depressive symptoms...
The present study evaluated the differential effects of two manipulations sleep—wake schedules on daily subjective ratings daytime sleepiness college undergraduate students. Two experimental conditions were compared: a sleep only group and regularity group. Subjects in both given lower limit for total time (7.5 hours). received an additional instruction to keep regular schedule. was longitudinal prospective. Following baseline period (12 days), introduced. phase lasted 4 weeks overall...
To estimate the efficacy of acupuncture for depression during pregnancy in a randomized controlled trial.A total 150 pregnant women who met Diagnostic and Statistical Manual Mental Disorders (Fourth Edition) criteria major depressive disorder were to receive either specific or one two active controls: control massage. Treatments lasted 8 weeks (12 sessions). Junior acupuncturists, not told about treatment assignment, needled participants at points prescribed by senior acupuncturists. All...
To examine the effects of cognitive behavioral therapy for insomnia (CBT-I) on suicidal ideation among Veterans with insomnia. Longitudinal data collected in course an uncontrolled evaluation a large-scale CBT-I training program. Outpatient and residential treatment facilities. Four hundred five presenting Cognitive At baseline, 32% patients, compared 21% at final assessment, endorsed some level [χ2(df = 1) 125; P < 0.001]. After adjusting demographic variables baseline severity, each...
Strong evidence supports the efficacy of cognitive behavioral therapy for insomnia (CBTI). A significant barrier to wide dissemination CBTI is lack qualified practitioners. We describe challenges and decisions made when developing a program in Veterans Health Administration (VHA). The targets mental health clinicians from different disciplines (psychiatry, psychology, social work, nursing) with varying familiarity experience general principles therapies (CBT). explain scope training (how...
Little is known about moderators of response to psychotherapy, medication, and combined treatment for chronic forms major depressive disorder (MDD). We hypothesized that patient preference at baseline would interact with group differentially affect outcome.We report outcomes 429 patients who participated in a randomized multicenter trial nefazodone, Cognitive Behavioral Analysis System Psychotherapy (CBASP), or combination therapy MDD (DSM-IV criteria) indicated their type study entry. The...
There is growing evidence suggesting that early adversity may be a marker for distinct pathway to major depressive disorder (MDD). We examined associations between childhood and broad variety of clinical characteristics response pharmacotherapy in large sample patients with chronic forms MDD.Subjects included 808 MDD (chronic MDD, double depression, or recurrent incomplete recovery episodes total continuous duration >2 years) who were enrolled 12-week open-label trial algorithm-guided...
This study tested whether the quality of patient-rated working alliance, measured early in treatment, predicted subsequent symptom reduction chronically depressed patients. Secondarily, assessed relationship between alliance and response to treatment differed patients receiving cognitive behavioral analysis system psychotherapy (CBASP) vs. brief supportive (BSP).