A5024812425- Ginseng Biological Effects and Applications
- Advancements in Transdermal Drug Delivery
- Agriculture, Soil, Plant Science
- Polysaccharides and Plant Cell Walls
- Biological and pharmacological studies of plants
- Phytoestrogen effects and research
- Pharmacological Effects of Natural Compounds
- Nanoplatforms for cancer theranostics
- Food Quality and Safety Studies
- Surfactants and Colloidal Systems
- Nanoparticle-Based Drug Delivery
- Advanced Polymer Synthesis and Characterization
- Dermatology and Skin Diseases
- Plant Stress Responses and Tolerance
- Aluminum toxicity and tolerance in plants and animals
- Wound Healing and Treatments
- Advanced Drug Delivery Systems
- GABA and Rice Research
- Immune cells in cancer
- Polymer-Based Agricultural Enhancements
- MicroRNA in disease regulation
- Mathematics, Computing, and Information Processing
- Chromatography in Natural Products
- Handwritten Text Recognition Techniques
- Graphene and Nanomaterials Applications
Kunming University of Science and Technology
2016-2025
Beijing Institute of Technology
2024
National University of Defense Technology
2024
Yunnan Metallurgical Group (China)
2018-2023
China Agricultural University
2023
State Administration of Traditional Chinese Medicine of the People's Republic of China
2018-2022
China University of Geosciences
2022
Dalian Jiaotong University
2021
Hainan University
2019
Kunming University
2018-2019
We here extracted a polysaccharide fragment from Gastrodia elata, characterized by main chain connected via (1 → 4)-α-D-Glcp bonds, with terminal α-D-Glcp-(1→) linked to the through O-6 of 4,6)-α-D-Glcp and O-3 3,4)-α-D-Glcp (SRGP). Both in vitro vivo experiments demonstrated that SRGP activates TLR4/NF-κB signaling pathway, exerting immunomodulatory effects alleviating cyclophosphamide (CTX)-induced intestinal mucosal damage mice. High-throughput 16S rRNA sequencing further revealed...
Soil fumigation with chloropicrin (CP) is an effective means of overcoming continuous cropping obstacles (CCO) in Panax notoginseng and improving its yield quality. CP can change the microbial community soil. Therefore, a key step after rapid restoration soil microorganisms promotion beneficial microorganism proliferation as dominant flora. In this study, continuously cropped P. was fumigated CP, general organic fertilizer (GOF) or (MOF) used to restore fumigation. physical chemical...
The sulfur dioxide gas (SO 2 ) generated by burning can improve the appearance quality of food and enhance storage time. However, excessive will pollute environment cause deterioration quality, even high residual levels increase risk cancer. As Gastrodia elata Blume is prone to corruption during processing, fumigation often used for preservation. In this study, spectral analysis Texture Profile Analysis (TPA) were investigate effects traditional processing on morphology edible structural...
In this work, imidazolium ionic liquids (imidazolium ILs) were employed as the novel chemical permeation enhancers (CPEs) and their performances mechanisms of action deeply investigated. Testosterone was used a model drug to investigate transdermal delivery enhancement twenty imdidazolium ILs. The results suggested that promotion activity connected structure composition quantitative structure-activity relationship (QSAR) revealed good linearity between electronic properties ILs enhancements....
UPLC-MS/MS and GC-MS/MS were used to establish a method simultaneously determine various pesticide residues in Panax notoginseng. Results showed that the limits of detection 249 pesticides all 5-10 μg/kg. The rate 121 P. notoginseng samples was 93.39%, 19 detected. According US Code Federal Regulations, Chinese Pharmacopoeia recommended algorithm, Japanese "positive list system", pass rates 100%, 99.17%, 89.26%, respectively. chronic risk quotient (ADI%) acute (ARfD%) 0.00-0.12% 0.00-0.15%,...
Panax notoginseng (Burk.) F. H. Chen is a Chinese medicinal plant of the Araliaceae family used for treatment cardiovascular and cerebrovascular diseases in Asia. P. vulnerable to root rot disease, which reduces yield notoginseng. In this study, we analyzed rhizosphere soil endophyte microbial communities from different geographical locations using high-throughput sequencing. Our results revealed that community was more diverse than community. Rhodopseudomonas, Actinoplanes, Burkholderia,...
Panax notoginseng (Burk.) F. H. Chen is a medicinal herb used to treat blood disorders since ancient times, of which the steamed form exhibits anti-anemia effect and acts with "blood-tonifying" function according traditional use. The present study aimed investigate underlying mechanism notogensing (SPN) on mice deficiency syndrome (BDS) induced by chemotherapy. BDS was in cyclophosphamide acetylphenylhydrazine. A number peripheral cells organs (liver, kidney spleen) coefficients were...
Natural polysaccharides are highly valued and extensively applied in drug delivery system for their desirable physical properties unique bioactivities. In this work, natural from Bletilla striata (BSP) were successfully extracted incorporated with Carbopol 940 to prepare hydrogels. Rheological behavior, skin permeation bioactivities of the BSP hydrogels evaluated. The rheological test showed better viscoelasticity strength gels gel. scanning laser confocal microscope (CLSM) trans-epidermal...
The present study aims to optimize the ethanol-reflux extraction conditions for extracting saponins from steamed Panax notoginseng (SPN). Four variables including time (0.5⁻2.5 h), ethanol concentration (50⁻90%), water solid ratio (W/S, 8⁻16), and times of (1⁻5) were investigated by using Box-Behnken design response surface methodology (BBD-RSM). For each response, a second-order polynomial model with high R² values (>0.9690) was developed multiple linear regression analysis optimum maximize...