A5079225993- Orthopedic Infections and Treatments
- Bone Tissue Engineering Materials
- Nanoparticle-Based Drug Delivery
- Synthesis and Characterization of Heterocyclic Compounds
- Drug Solubulity and Delivery Systems
- Nanoplatforms for cancer theranostics
- Bone health and treatments
- Curcumin's Biomedical Applications
- Polymer Synthesis and Characterization
- Engineering Technology and Methodologies
- Oral microbiology and periodontitis research
- Endodontics and Root Canal Treatments
- Medical and Biological Ozone Research
- Radiation Therapy and Dosimetry
Federal Medical-Biological Agency
2023-2025
D. Mendeleyev University of Chemical Technology of Russia
2020-2024
This research aimed to evaluate the potency of preparation based on heparinized iron oxide nanoparticles (hIONPs) in combination with radiation therapy, including magnetic delivery via applied field (AMF), sarcoma and cervical cancer models. For vitro studies, cells rhabdomyosarcoma (RD), fibrosarcoma (HT1080), (HeLa S3) were treated hIONPs analyzed for survival rate hIONP uptake. Then, cell morphology, cycle, increase reactive oxygen species, mitochondria depolarization, ability form...
Abstract The immobilization of a broad‐spectrum antibiotic amikacin on macromolecules dextran previously modified with epichlorohydrin is described. It shown that the release observed only in presence dextranase, which produced by bacteria. For first time, biocomposite materials based Glisson capsule liver and pericardium, containing layer grafted acting as carrier capable releasing derivatives have antibacterial activity case infection, been developed. was found rate formed dextranase...
BACKGROUND: Nanocarriers based on biocompatible polymers are a promising delivery tool for biologically active substances and drugs, in particular antitumor agents. Curcumin, polyphenol, is known to possess pleiotropic therapeutic effects, including activity. The potential of curcumin has been shown various tumor types, ovarian adenocarcinoma. However, its lipophilic properties very low bioavailability limits use. Incorporating into nanocarriers enhances options expands as an agent. AIM: To...
Methodology Papers -Papers that present different methodological approaches can be used to investigate problems in a relevant scientific field and encourage innovation.
A polysaccharide gel containing covalently bound amikacin, a broad-spectrum antibiotic, was produced by using epichlorohydrin-activated hydroxyethyl starch (HES). The structure of the polymers analyzed 13C and 1H nuclear magnetic resonance (13C NMR NMR) matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. sites covalent attachment amikacin to epoxypropyl substituent HES backbone were determined. antibacterial activity polymer evaluated in vitro agar well...
Methodology Papers -Papers that present different methodological approaches can be used to investigate problems in a relevant scientific field and encourage innovation.