A5108134086- Cancer Immunotherapy and Biomarkers
- Intracerebral and Subarachnoid Hemorrhage Research
- Lung Cancer Research Studies
- Neurosurgical Procedures and Complications
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Treatments and Mutations
- Acute Ischemic Stroke Management
- Neuroscience and Neuropharmacology Research
- PI3K/AKT/mTOR signaling in cancer
- Peripheral Artery Disease Management
- Angiogenesis and VEGF in Cancer
- Neurotransmitter Receptor Influence on Behavior
- Cancer Cells and Metastasis
- Ferroptosis and cancer prognosis
- Brain Metastases and Treatment
- Glioma Diagnosis and Treatment
- Monoclonal and Polyclonal Antibodies Research
- Spinal Hematomas and Complications
- Mosquito-borne diseases and control
- Berberine and alkaloids research
- Vascular Procedures and Complications
- Growth Hormone and Insulin-like Growth Factors
- Epilepsy research and treatment
- Media Influence and Health
- Immune Cell Function and Interaction
Gansu Provincial Hospital
2018-2025
Binghamton University
2025
Zhejiang University
2024
Tongji University
2024
Shanghai First People's Hospital
2023-2024
University of Notre Dame
2024
Fudan University
2018-2024
Anhui Provincial Hospital
2022-2024
Hunan Normal University
2024
Hunan Provincial People's Hospital
2024
Locomotor activity is a polygenic trait that varies widely among inbred strains of mice (Flint et al., 1995). To characterize the role D2 dopamine receptors in locomotion, we generated F 2 hybrid (129/Sv × C57BL/6) receptor (D2R)-deficient by gene targeting and investigated contribution genetic background to open-field rotarod performance. Horizontal D2R−/− was approximately half drug-naive, strain-matched controls but significantly greater than haloperidol-treated controls, which were...
There is growing concern that chemotherapy drugs can damage Leydig cells and inhibit the production of testosterone. Increasing evidence shows melatonin benefits reproductive process. This study mainly explores protective effect possible molecular mechanism regarding cisplatin-induced oxidative stress in testicular tissue cells. We found there were only Sertoli testes gastrointestinal tumor patients with azoospermia caused by platinum chemotherapeutic drugs. Melatonin (Mel) receptor...
Background: Proficient surgical skills are essential for surgeons, making training an important part of education. The development technology promotes the diversification types. This study analyzes changes in patterns from perspective bibliometrics, and applies learning curves as a measure to demonstrate their teaching ability. Method: Related papers were searched Web Science database using following formula: TS=((training OR simulation) AND (learning curve) (surgical)). Two researchers...
Maintenance hemodialysis (MHD) is a commonly used renal replacement therapy for end-stage disease patients. MHD patients have undergone multiple physiological stressors, which may cause physical problems and affect their mental health; however, few qualitative studies been done on the health of Such research becomes basis further quantitative critical to validating its results. Therefore, current study semi-structured interview format, aimed explore influencing factors who are not receiving...
Abstract Objectives To develop a multiparameter magnetic resonance imaging (MRI)-based radiomics approach that can accurately predict the tumor cell proliferation status of serous ovarian carcinoma (SOC). Materials and methods A total 134 patients with SOC who met inclusion exclusion criteria were retrospectively screened from institution A, spanning January 2016 to March 2022. Additionally, an external validation set comprising 42 B was also included. The region interest determined by...
Admission hyperglycaemia is very common in acute ischaemic stroke (IS) patients and associated with worse outcome non-lacunar infarction, but its association lacunar infarction remains controversial. We investigated the between clinical a hospitalised Chinese population. Consecutive IS were enrolled classified into groups based on criteria according to Oxfordshire Community Stroke Project (OCSP) findings brain computed tomography (CT) or magnetic resonance imaging (MRI) scan. Hyperglycaemia...
Lung cancer is a neoplasm with 5-year survival rate of less than 15 % and leading cause death worldwide, despite recent progress in treatment diagnostic methods. stem-like cells (CSCs) are pivotal lung metastasis drug resistance. This study aimed to develop CSCs that stably express stem cell properties through transfection further screen traditional Chinese herbal compounds. adenocarcinoma cells, which include various phenotypic subgroups, normally characterized by high expression levels...
In this study, the antioxidant and hypolipidemic effects of Mesona Chinensis Benth (MCB) extracts were evaluated. Seven fractions (F0, F10, F20, F30, F40, F50 MTF) obtained from MCB ethanol extracts. Compared to commercial antioxidants (vitamin C), MTF F30 exhibited higher activities in antiradical activity test FRAP assay. The half-inhibition concentration (IC50) for 5.323 µg/mL 5.278 µg/mL, respectively. at 200 significantly decreased accumulation TG oleic acid (OA)-induced HepG2 cells...
The choice of surgical or conservative treatment for patients with spontaneous intracerebral hemorrhage is controversial. Some minimally invasive treatments have been applied to hematoma evacuation and could improve prognosis some extent. Up now, studies on surgery are still insufficient.The MISTICH a multi-center, prospective, randomized, assessor-blinded, parallel group, controlled clinical trial. 2448 eligible will be assigned neuroendoscopy stereotactic aspiration group craniotomy...
Studies on antihypertensive treatment for surgical patients with spontaneous intracerebral hemorrhage are insufficient. This pilot study was conducted to investigate the safety of perioperative intensive blood pressure lowering in hemorrhage.This a prospective, parallel, randomized, assessor-blinded trial. Patients allocated group received aiming achieve target systolic between 120 and 140 mm Hg, whereas conservative 180 Hg 7 days. The primary outcome rate rehemorrhage at days after...
Improvement in left ventricular ejection fraction (impEF) often presents contemporary acute myocardial infarction (AMI) patients. New-onset atrial fibrillation (NOAF) during AMI is an important predictor of subsequential heart failure (HF), while its impact on the trajectory post-MI (LVEF) and prognostic implication patients with without impEF remains undetermined. We aimed to investigate impacts NOAF impEF.