A5037584770- Prenatal Screening and Diagnostics
- MicroRNA in disease regulation
- Reproductive Biology and Fertility
Peking University
2022
National Clinical Research Center for Digestive Diseases
2022
Ministry of Education of the People's Republic of China
2022
Peking University Third Hospital
2022
Mechanisms of implantation such as determination the attachment pole, fetal-maternal communication, and underlying causes failure are largely unexplored. Here, we performed single-cell RNA sequencing on peri-implantation embryos from both humans mice to explore trophectoderm (TE) development embryo-endometrium cross-talk. We found that transcriptomes polar mural TE diverged after hatched zona pellucida in species, with being more mature than TE. The poles show similarities cell cycle...