- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- S100 Proteins and Annexins
- Systemic Lupus Erythematosus Research
- Cell Adhesion Molecules Research
- T-cell and B-cell Immunology
- Extracellular vesicles in disease
- Immune Cell Function and Interaction
- Bladder and Urothelial Cancer Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- MicroRNA in disease regulation
- Lung Cancer Treatments and Mutations
- Axon Guidance and Neuronal Signaling
- Hepatocellular Carcinoma Treatment and Prognosis
- Knowledge Management and Sharing
- Digital Marketing and Social Media
- Cancer Cells and Metastasis
- Fibroblast Growth Factor Research
- Tuberculosis Research and Epidemiology
- Immune cells in cancer
- Lung Cancer Diagnosis and Treatment
- Reproductive System and Pregnancy
- Autophagy in Disease and Therapy
- Immunotherapy and Immune Responses
- Technology Adoption and User Behaviour
Nantong University
2022-2025
Affiliated Hospital of Nantong University
2022-2025
Renmin University of China
2024
China University of Geosciences (Beijing)
2024
Chengdu Third People's Hospital
2020
First Affiliated Hospital of Zhengzhou University
2016
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that affects various organs and systems, significantly impacting patients' health quality of life. Conventional drugs, including glucocorticoids standard immunosuppressive may not be enough to achieve satisfactory therapeutic outcome in some refractory SLE patients. The abnormal phenotype function macrophages participate the development SLE. targeted delivery reprogram macrophage has been long-standing challenge. Apoptotic...
The peripheral B cell compartment is heavily disturbed in systemic lupus erythematosus (SLE), but whether cells develop aberrantly the bone marrow (BM) largely unknown.
The application of OpenAI's advanced artificial intelligence language model, ChatGPT, in education has garnered widespread attention from the academic community. openness and features ChatGPT demonstrate great potential value supporting students' learning, daily life, communication. This study, grounded theoretical frameworks Innovation Diffusion Theory (IDT) Technology Acceptance Model (TAM), conducted a systematic empirical analysis through questionnaire survey 677...
Abstract (−)-Guaiol is a sesquiterpenoid found in many traditional Chinese medicines with potent antitumor activity. However, its therapeutic effect and mechanism non-small cell lung cancer (NSCLC) have not been fully elucidated. In this study, was to induce immunogenic death (ICD) NSCLC vitro. Using vivo, we that could suppress tumor growth, increase dendritic activation, enhance T-cell infiltration. Vaccination experiments suggest cellular immunoprophylaxis after intervention can growth....
Systemic lupus erythematosus (SLE) is a chronic and systemic autoimmune disease characterized by dysregulation in both innate adaptive immunity. Polarization of macrophages into M1/M2 affects the development lupus. Exosomes-miRNA plays crucial role progression. This study aims to explore mechanism circulating exosomes participating pathogenesis SLE seek new therapeutic targets. Plasma derived-exosomes from patients accelerated progression polarization kidney MRL/lpr mice. Exosomes were taken...
The clinical significance of thymosin β4 (Tβ4) expression in bladder transitional cell carcinoma (BTCC) remains unclear. present study assessed the relationship between Tβ4 protein and clinicopathological features, as well prognosis cancer patients. 24 normal 138 primary BTCC tissue specimens was detected by immunohistochemistry, association this with features recurrence patient survival analyzed. significantly stronger patients than volunteers. associated differentiation capability, tumor...
In systemic lupus erythematosus (SLE), neutrophil dysregulation and extracellular traps (NETs) formation contribute to disease pathogenesis, potentially worsening the autoimmune response. Although research indicates NETs' involvement in various conditions, their relationship with regulatory T cells (Tregs) SLE remains elusive. this study, vivo experiments were involved administering NET injections C57BL/6 MRL/Ipr mice. vitro, a co-culture system facilitated interaction between Tregs NETs....