Tubanur ASLAN ENGİN

ORCID: 0000-0003-2885-8829
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About
Contact & Profiles
Research Areas
  • Lichen and fungal ecology
  • Medicinal plant effects and applications
  • Hedgehog Signaling Pathway Studies
  • Fungal Biology and Applications
  • Biological Activity of Diterpenoids and Biflavonoids
  • Science Education and Pedagogy
  • Phytochemistry and Bioactivity Studies
  • Mycorrhizal Fungi and Plant Interactions
  • Animal and Plant Science Education
  • Plant Pathogens and Fungal Diseases
  • Drug-Induced Hepatotoxicity and Protection
  • Natural Compounds in Disease Treatment
  • Pharmacological Effects of Natural Compounds
  • Education and Critical Thinking Development
  • Mycotoxins in Agriculture and Food
  • Curcumin's Biomedical Applications
  • Bryophyte Studies and Records
  • Liver Disease Diagnosis and Treatment

Yalova University
2022-2025

Kafkas University
2018-2021

Hakkari University
2021

Lichens are symbiotic organisms that produce a variety of secondary metabolites, including the well-known usnic acid (C18H16O7), which has garnered attention for its diverse biological activities and potential applications. Usnic acid, primarily found in lichen species such as Usnea Cladonia, is yellowish-green compound with notable antimicrobial, antiviral, anti-inflammatory properties. Its antioxidant activity particularly significant, ability to neutralize free radicals, inhibit lipid...

10.51753/flsrt.1572004 article EN Frontiers in Life Sciences and Related Technologies 2025-04-30

Herbal medicines are efficient to reduce side effects in the fight against glioblastoma, which plays a critical role within brain cancer species. The recent studies designated for testing of lichens that have shown numerous anticancer activities on glioblastoma so far. In present study, different concentrations water extract obtained from Usnea longissima Ach. were used order determine cytotoxic (via 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and lactate dehydrogenase...

10.1590/0001-3765201920180994 article EN cc-by Anais da Academia Brasileira de Ciências 2019-01-01

There are different herbal methods used for support in many cancer diseases.Lichens important organisms containing unique compounds and it is known that they have anticancer activities.Starting from these features, the present study was aimed to investigate activity of friedelin (FRI), a lichen compound against glioblastoma multiforme (GBM) showed dangerous malignant properties within brain species.It human U87MG-GBM cell lines primary rat cerebral cortex (PRCC) non-cancerous cells isolated...

10.5578/fmbd.67733 article EN Afyon Kocatepe University Journal of Sciences and Engineering 2018-12-01

The biological activities of lichens, known as organisms based on a symbiotic relationship, are attracting more and attention in traditional medicine modern drug research. Lichens can possess various pharmacological effects such antimicrobial, antioxidant, antitumor, anti-inflammatory, many others due to the bioactive compounds they contain. In present study, Usnea longissima Ach. its secondary metabolite, usnic acid human gastric adenocarcinoma cells (AGS), colorectal (Caco-2), mouse...

10.30616/ajb.1343823 article EN Anatolian Journal of Botany 2023-09-03

The aim of this study was to investigate the antifungal effects and molecular changes caused by Usnea longissima Ach. extracts against Fusarium greaminearum. In agar well diffusion assay, zone inhibition increased as concentration in both methanol acetone (1, 10, 20 50 mg/ml). terms bioactivities, 1 mg/ml active, while other concentrations were very active. At level, extract analyzed qPCR with cat, mst20, tri5 genes, which are associated antioxidation, apoptosis, trichothecene production,...

10.30616/ajb.1172113 article EN Anatolian Journal of Botany 2022-09-26

In this study, acetone and water extracts obtained from edible mushrooms, Rhizopogon luteolus Fr. Rh. roseolus (Corda) Th. Fr., containing important bioactive components were used. Total antioxidant capacity (TAC) total oxidative stress (TOS) levels examined on human peripheral lymphocyte culture treated with the respective extracts. Levels of genetic damage cytotoxic effects lymphocytes also tested. general, when TAC cells examined, a concentration-dependent increase was observed; negative...

10.1615/intjmedmushrooms.2021037653 article EN International journal of medicinal mushrooms 2021-01-01

Aim: We therefore wanted to investigate acetaminophen hepatotoxicity by using Hep3B human hepatoma cells exposed and resveratrol, used as a protective agent. Specifically, we studied the role of some proinflammatory markers oxidative damage possible mechanisms acetaminophen-associated cytotoxicity.
 Materials Method: The cell line was for this study. In vitro studies (GSH, SOD, CAT, AST, ALT, TNF-alpha, IL-6 viability) were performed different methods such Biochemical analyzer, RT-PCR,...

10.38001/ijlsb.1357213 article EN International Journal of Life Sciences and Biotechnology 2023-10-23

The aim of this study is to investigate the effect concept cartoons and biology teaching based on a constructivist learning approach student achievement permanence knowledge. group consists 49 students studying in two 10th digital classes Kazım Karabekir Technical Industrial Vocational High School Yunus Emre district Erzurum. At stage data collection, tests including three-stage pre-test, post-test test consisting 25 questions related subject “Ecosystem Ecology”, which third unit course,...

10.51753/flsrt.824378 article EN cc-by Frontiers in Life Sciences and Related Technologies 2021-02-03
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