- Microbial Community Ecology and Physiology
- Gut microbiota and health
- Genomics and Phylogenetic Studies
- Evolution and Genetic Dynamics
- Soil Carbon and Nitrogen Dynamics
- Evolutionary Game Theory and Cooperation
- Mycorrhizal Fungi and Plant Interactions
- Indoor Air Quality and Microbial Exposure
- Atmospheric and Environmental Gas Dynamics
- Methane Hydrates and Related Phenomena
- Probiotics and Fermented Foods
- Bacteriophages and microbial interactions
- Ecology and Vegetation Dynamics Studies
- Aquaculture disease management and microbiota
- Species Distribution and Climate Change
- Mathematical and Theoretical Epidemiology and Ecology Models
- Plant and animal studies
- Epigenetics and DNA Methylation
- Polar Research and Ecology
- Insect symbiosis and bacterial influences
- Vibrio bacteria research studies
- Peatlands and Wetlands Ecology
- Forest Ecology and Biodiversity Studies
- Cassava research and cyanide
- Wastewater Treatment and Nitrogen Removal
University of Oregon
2016-2025
Eugene Research Institute
2021
La Jolla Alcohol Research
2010-2014
Princeton Public Schools
2009-2010
Missoula County Public Schools
2010
Madison Group (United States)
2010
Berkeley College
2010
Stanford University
1999-2008
University of Illinois Urbana-Champaign
2008
Institute for Systems Biology
2006
Abstract The reconstruction of bacterial and archaeal genomes from shotgun metagenomes has enabled insights into the ecology evolution environmental host-associated microbiomes. Here we applied this approach to >10,000 collected diverse habitats covering all Earth’s continents oceans, including human animal hosts, engineered environments, natural agricultural soils, capture extant microbial, metabolic functional potential. This comprehensive catalog includes 52,515 metagenome-assembled...
Mathematical models predict that the future of multidrug-resistant tuberculosis epidemic will depend on fitness cost drug resistance. We show in laboratory-derived mutants Mycobacterium tuberculosis, rifampin resistance is universally associated with a competitive and this determined by specific mutation strain genetic background. In contrast, we demonstrate prolonged patient treatment can result strains no defect low- or no-cost mutations are also most frequent among clinical isolates.
The Amazon rainforest is the Earth’s largest reservoir of plant and animal diversity, it has been subjected to especially high rates land use change, primarily cattle pasture. This conversion had a strongly negative effect on biological reducing number species homogenizing communities. We report here that microbial biodiversity also responds rainforest, but in manner different from plants animals. Local taxonomic phylogenetic diversity soil bacteria increases after conversion, communities...
A major goal of community ecology is to link biological processes at lower scales with patterns. Microbial communities are especially powerful model systems for making these links. In this article, we review recent studies laboratory bacteria and bacteriophage (viruses that infect bacteria). We focus on the evolution bacteriophage‐resistance as a case study demonstrating relationship between specific genes, individual interactions, population dynamics, structure, evolutionary change....
Abstract Buildings are complex ecosystems that house trillions of microorganisms interacting with each other, humans and their environment. Understanding the ecological evolutionary processes determine diversity composition built environment microbiome—the community live indoors—is important for understanding relationship between building design, biodiversity human health. In this study, we used high-throughput sequencing bacterial 16S rRNA gene to quantify relationships attributes airborne...
Significance Recent surveys of the microbial communities living on and in human body—the microbiome—have revealed strong variation community membership between individuals. Some this is stable over time, leading to speculation that individuals might possess unique “fingerprints” distinguish them from population. We rigorously evaluated idea by combining concepts ecology computer science. Our results demonstrated could be uniquely identified among populations 100s based their microbiomes...
Architects and engineers are beginning to consider a new dimension of indoor air: the structure composition airborne microbial communities. A first step in this emerging field is understand forces that shape diversity bioaerosols across space time within built environment. In an effort elucidate relative influences three likely drivers bioaerosol - variation outdoor bioaerosols, ventilation strategy, occupancy load we conducted intensive temporal study bacterial communities high-traffic...
Very little is known about the structure of microbial communities, despite their abundance and importance to ecosystem processes. Recent work suggests that bacterial biodiversity might exhibit patterns similar those plants animals. However, relative our knowledge diversity macro-organisms, we know relatedness in free-living relatively few studies have quantitatively examined community a phylogenetic framework. Here apply tools data determine whether communities are phylogenetically...