A5038100088- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Advanced Nanomaterials in Catalysis
- Electrochemical sensors and biosensors
- Advanced Photocatalysis Techniques
- Polymer Surface Interaction Studies
- Nanocluster Synthesis and Applications
- CO2 Reduction Techniques and Catalysts
- Ammonia Synthesis and Nitrogen Reduction
- CRISPR and Genetic Engineering
- Identification and Quantification in Food
- Gold and Silver Nanoparticles Synthesis and Applications
- Bacteriophages and microbial interactions
- Electrochemical Analysis and Applications
- SARS-CoV-2 detection and testing
- Force Microscopy Techniques and Applications
- Molecular Junctions and Nanostructures
- Cancer Research and Treatments
- Catalytic Processes in Materials Science
- Gas Sensing Nanomaterials and Sensors
- Advanced Biosensing Techniques and Applications
- Signaling Pathways in Disease
- Genomics, phytochemicals, and oxidative stress
- Evolution and Genetic Dynamics
- Electrocatalysts for Energy Conversion
Washington State University
2018-2025
China Agricultural University
2016-2025
Ministère de l'Agriculture et de la Souveraineté alimentaire
2025
Nanjing University of Chinese Medicine
2025
University of East Anglia
2024
Taiyuan University of Technology
2021-2024
Ministry of Agriculture and Rural Affairs
2023-2024
Jiangnan University
2023
Hefei Normal University
2021-2022
Xidian University
2019-2021
Nanozymes are an excellent class of optical reporters for the development sensitive biosensors widespread applications. In this study, mesoporous core-shell palladium@platinum (Pd@Pt) nanoparticles were synthesized and then applied as signal amplifier in a dual lateral flow immunoassay (LFIA) integrated with smartphone-based device use simultaneous detection Salmonella Enteritidis Escherichia coli O157:H7. After optimization, limit detections calculated to be ∼20 cfu/mL S. ∼34 E. O157:H7,...
Abstract Single‐atom catalysts are becoming a hot research topic owing to their unique characteristics of maximum specific activity and atomic utilization. Herein, new single‐atom nanozyme (SAN) based on single Fe atoms anchored N‐doped carbons supported carbon nanotube (CNT/FeNC) is proposed. The CNT/FeNC with robust Fe–N x moieties synthesised, showing superior peroxidase‐like activity. Furthermore, the used as signal element in series paper‐based bioassays for ultrasensitive detection H 2...
A new cysteine-based methacrylic monomer (CysMA) was conveniently synthesized via selective thia-Michael addition of a commercially available methacrylate-acrylate precursor in aqueous solution without recourse to protecting group chemistry. Poly(cysteine methacrylate) (PCysMA) brushes were grown from the surface silicon wafers by atom-transfer radical polymerization. Brush thicknesses ca. 27 nm achieved within 270 min at 20 °C. Each CysMA residue comprises primary amine and carboxylic acid....
This article describes the aqueous atom transfer radical polymerization synthesis of poly(3-sulfopropylmethacrylate) brushes onto gold and Si/SiO2 surfaces in a controlled manner. The effect Cu(I)/Cu(II) ratio was examined, quartz crystal microbalance used to study kinetics brush synthesis. synthesized displayed thickness from few nanometers several hundred were characterized using atomic force microscopy, ellipsometry, Fourier transform infrared spectroscopy (FTIR), contact angle...
Emerging nanomaterials such as nanozymes have recently been applied for the immunoassay-based detection of biomarkers. However, inferior catalytic activity and low water solubility remain major limitations compared to natural enzymes. To overcome these limitations, we successfully synthesized a superior nanozyme with structure enriched 2D interface, namely Nanozyme Nest, which was composed Fe-based metal-organic frameworks (Fe-MOF) graphene oxide (GO). Then, it in an ultrasensitive...
Conventional lateral flow biosensing technologies face the dual formidable challenges of poor sensitivity and cumbersome quantitative devices. Here, we developed a Au@Pd nanopopcorn aptamer nanoflower assisted strip (ANAN-LFS) with thermal signal output to improve detection sensitivity. Moreover, smartphone-based reader was designed meticulously optimized hand-held style, realizing essential portability this device. Experimental studies revealed that synthesized nanopopcorns clearly...
Since the first report in 1950s, immunosensors and immunoassays with good specificity have got extensive applications clinical diagnosis, food safety, environmental monitoring. As a typical type of immunosensors, enzyme-linked immunosorbent assays (ELISAs) are able to offer high sensitivity for target sensing because catalytically amplified readouts produced by their enzyme labels (horseradish peroxidase, alkaline phosphatase, et al.). However, use these natural enzymes brings some undesired...
Climate change and the growing world population leading to agriculture food safety are global challenges facing humanity, while biosensors have long been regarded as one of powerful tools for providing solutions. Biosensors can aid in sustainable by continuous monitoring or early detection disease outbreaks that be averted. It also plays an important role risk factors such pesticides, veterinary medications, heavy metals, pathogens, poisons, illegal additions. Currently, this field includes...
Food safety is closely related to human health. However, the regulation and testing processes for food are intricate resource-intensive. Therefore, it necessary address risks using a combination of deep learning, Internet Things, smartphones, quick response codes, smart packaging, other technologies. Intelligent designs that combine digital systems advanced functionalities with biosensors hold great promise revolutionizing current practices. This review introduces concept Safety 4.0,...
This paper describes detailed studies on the controlled synthesis of poly[2-(methacryloyloxy)ethyl]dimethyl(3-sulfopropyl)ammonium hydroxide (polyMEDSAH) from initiator-modified gold surfaces and properties these brushes as a function grafting density thickness. Improved control over polymerization was achieved by preforming catalytically active complex to ensure that monomers did not coordinate catalyst. We observed an intriguing transition thickness (hcrit) in which polyMEDSAH switched...
Recent outbreaks of life-threatening neonatal infections linked to Enterobacter sakazakii (ES) heightened the need develop rapid and ultrasensitive detection strategies, especially those capable determining viable cells. This study introduced a continual cascade nanozyme biosensor for ES based on propidium monoazide (PMA), loop-mediated isothermal amplification (LAMP), Nanozyme strip. The ompA gene was determined using FITC-modified BIO-modified primers in LAMP process. combined with PMA...
Single-atom nanozymes (SANs) possess unique features of maximum atomic utilization and present highly assembled enzyme-like structure remarkable activity. By introducing SANs into immunoassay, limitations ELISA such as low stability horseradish peroxidase (HRP) can be well addressed, thereby improving the performance immunoassays. In this work, we have developed novel Fe-N-C single-atom (Fe-Nx SANs) derived from Fe-doped polypyrrole (PPy) nanotube substituted enzymes in kit for enhancing...
In this study, a whole-course nucleic-acid-constructed biosensor that combines the all-in-one concepts of universal blocking linker recombinase polymerase amplification (UBLRPA) and peptide nucleic acid (PNA)-based lateral flow device (PLFD) has been developed for ultrasensitive detection food pathogens. Using preamplification UBLRPA principle, C3 space blocker were utilized to produce single-duplex DNA products. The system was employed convert duplex products single strand. signal...
Nanoscale cerium oxide has excellent catalytic performance due to its unique surface properties and very important applications in various fields. In this paper, the synthesis methods, mechanism activity regulation of nanoscale recent years are reviewed. Secondly, application detection organic inorganic molecules is summarized, latest progress antibacterial, antioxidant anticancer discussed. Finally, future development prospect summarized prospected.