A5057335951- Musculoskeletal pain and rehabilitation
- Glioma Diagnosis and Treatment
- Pain Management and Treatment
- Anesthesia and Pain Management
- Transcranial Magnetic Stimulation Studies
- Diet and metabolism studies
- Spine and Intervertebral Disc Pathology
- Cancer, Hypoxia, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Metabolomics and Mass Spectrometry Studies
- Cerebral Venous Sinus Thrombosis
- Pharmacological Effects and Toxicity Studies
- Biomedical and Engineering Education
- Mobile Health and mHealth Applications
- Vestibular and auditory disorders
- Nanoparticle-Based Drug Delivery
- Pain Mechanisms and Treatments
- COVID-19 and healthcare impacts
- Myofascial pain diagnosis and treatment
- Immune cells in cancer
- Migraine and Headache Studies
- Telemedicine and Telehealth Implementation
- Pain Management and Placebo Effect
- Brain Metastases and Treatment
- Laser Applications in Dentistry and Medicine
Umeå University
2008-2025
University Hospital of Umeå
2021-2023
The knowledge of response to radiation in the immuno-microenvironment high grade gliomas is sparse. In vitro results have indicated an inflammatory myeloid cells after irradiation. Therefore, microdialysis was used verify whether this operative tumor tissue and brain adjacent (BAT) clinical radiotherapy patients with glioma. Stereotactic biopsies implantation catheters BAT were performed eleven high-grade given daily fractions 2–3.4 Gy. Microdialysis samples collected before during first...
High-grade gliomas are associated with poor prognosis. Tumour heterogeneity and invasiveness create challenges for effective treatment use of systemically administrated drugs. Furthermore, lack functional predictive response-assays based on drug efficacy complicates evaluation early responses.We used microdialysis to deliver cisplatin into the tumour monitor levels metabolic compounds present in non-malignant brain tissue adjacent tumour, before during treatment. In parallel, we collected...
Pain, comprising sensory and emotional elements, is influenced by pain catastrophizing, which magnifies promotes helplessness rumination. This study explores the relationship between catastrophizing outcomes following selective nerve root blockade (SNRB) in patients with lumbar radicular (LRP). A prospective cohort of 103 LRP patients, confirmed MRI, was conducted. All participants underwent SNRB at Umeå University Hospital. Outcomes were measured using PROMIS-29 Pain Catastrophizing Scale...
The increasing adoption of digital health care solutions offers a transformative opportunity to improve patient access while addressing sustainability and cost-efficiency challenges. Our study evaluates virtual remote system (VRCS) that has been implemented at our clinic in northern Sweden. By combining patient-centered outcomes, environmental metrics, economic models, this examines the impact VRCS on satisfaction, resource utilization, sustainability. Eighty patients with chronic pain,...
Selective nerve root blocks (SNRB) are used both as a therapeutic and diagnostic tool for lumbar radicular pain. Most studies evaluate the effect of SNRB simply by its relation to pain reduction. It is well known that associated with other factors such depression, anxiety, inactivity sleeping disorders, but these patient-related outcomes seldom evaluated. This study evaluated influence on pain-related including fatigue, interference, activity sleep. One hundred three patients were treated...
Management of patients with persisting pain after spine surgery (PPSS) shows significant variability, and there is limited evidence from clinical studies to support treatment choice in daily practice. This study aimed develop patient-specific recommendations on the management PPSS. Using RAND/UCLA appropriateness method (RUAM), an international panel 6 neurosurgeons, specialists, orthopaedic surgeons assessed 4 options (conservative, minimally invasive, neurostimulation, re-operation) for...
Chronic low back pain (CLBP) is one of the most common chronic conditions that cause both individual suffering and a burden to society. For these patients, several interventional treatment options such as surgery, blocks, radiofrequency, spinal cord stimulation are available. Lately, dorsal root ganglion (DRG-S) also has been mentioned an option by targeting bilateral T12 ganglia. In this study, we present outcome 11 patients with CLBP treated DRG-S.
Abstract Background Dorsal root ganglion stimulation (DRG‐S) has emerged as a novel therapeutic approach for managing chronic neuropathic pain. Aims This study aims to compare the effectiveness of 4–20 Hz DRG‐S through retrospective analysis cohort 28 patients with various pain etiologies and locations. Materials Methods Patient responses both frequencies were examined using Numeric Rating Scale (NRS) Global Impression Change (PGIC) assessments. Factors such patient preference satisfaction...