A5082311090- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Insect Utilization and Effects
- Invertebrate Immune Response Mechanisms
- Vibrio bacteria research studies
- Genomics and Phylogenetic Studies
- RNA modifications and cancer
- CRISPR and Genetic Engineering
- RNA and protein synthesis mechanisms
- vaccines and immunoinformatics approaches
- Cancer-related molecular mechanisms research
- Insect symbiosis and bacterial influences
Monash University Malaysia
2021-2024
Galleria mellonella larvae have been increasingly used in research, including microbial infection studies. They act as suitable preliminary models to study host-pathogen interactions due their advantages, such the ability survive at 37°C mimicking human body temperature, immune system shares similarities with mammalian systems, and short life cycle allowing large-scale Here, we present a protocol for simple rearing maintenance of G. without requiring special instruments specialized training....
Abstract Objective The nosocomial pathogen, Acinetobacter baumannii, has acquired clinical significance due to its ability persist in hospital settings and survive antibiotic treatment, which eventually resulted the rapid spread of this bacterium with antimicrobial resistance (AMR) phenotypes. This study used a multidrug-resistant A. baumannii (strain ATCC BAA1605) as model genomic features pathogen. Results One circular chromosome one plasmid were discovered complete genome BAA1605 using...
Acinetobacter species are widely known opportunistic pathogens causing severe community and healthcare-associated infections. One such emerging pathogen, colistiniresistens, is to exhibit intrinsic resistance colistin. We investigated the molecular characteristics of A. colistiniresistens strain C-214, isolated from fecal sample a healthy member, as part cohort study being conducted in Segamat, Malaysia. Comparison whole genome sequence C-214 with other sequences retrieved NCBI database...
Abstract Acinetobacter baumannii is a top-priority pathogen as classified by the World Health Organisation. It causes life-threatening infections in immunocompromised patients, resulting prolonged hospitalisation and high mortality. Increasing cases of community-acquired A. with rapid progression severe have been reported. This study used previously described Galleria mellonella infection model to investigate virulence mechanisms community strain C98 (Ab-C98) via transcriptomic analysis...
Acinetobacter baumannii , a top‐priority WHO pathogen, causes life‐threatening infections in immunocompromised patients, leading to prolonged hospitalisation and high mortality. Here, we used the Galleria mellonella model investigate community strain C98 (Ab‐C98) virulence via transcriptomic analysis. Ab‐C98 showed greater killing faster colonisation larvae than clinical reference (ATCC BAA1605). Genes three iron clusters, acinetobactin, baumannoferrin Feo system, were significantly...
Despite being a major human pathogen, limited studies have reported RNA modifications in
Galleria mellonella larvae have been increasingly used in various scientific research, including microbial infection studies. They act as suitable preliminary models to study host-pathogen interactions due their advantages, such the ability survive at 37 °C mimicking human body temperature, immune system shares similarities with mammalians, etc. Here, we presented a protocol for simple rearing and maintenance of science research laboratories without requiring special instruments specialised...
Galleria mellonella larvae have been increasingly used in various scientific research, including microbial infection studies. They act as suitable preliminary models to study host-pathogen interactions due their advantages, such the ability survive at 37 °C mimicking human body temperature, immune system shares similarities with mammalians, etc. Here, we presented a protocol for simple rearing and maintenance of science research laboratories without requiring special instruments specialised...