- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Reproductive System and Pregnancy
- Gynecological conditions and treatments
- Intestinal and Peritoneal Adhesions
- Pregnancy and preeclampsia studies
- Ovarian function and disorders
- Extracellular vesicles in disease
- Solid State Laser Technologies
- Pregnancy-related medical research
- Endometrial and Cervical Cancer Treatments
- Heavy Metal Exposure and Toxicity
- Ureteral procedures and complications
- Ectopic Pregnancy Diagnosis and Management
- Fluoride Effects and Removal
- Ovarian cancer diagnosis and treatment
- Arsenic contamination and mitigation
- Pelvic floor disorders treatments
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
Istituti di Ricovero e Cura a Carattere Scientifico
2017-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017-2024
Vita-Salute San Raffaele University
2017-2024
San Raffaele University of Rome
2020-2023
Endometriosis
2022
A network of endometriosis experts from 16 Italian academic departments and teaching hospitals distributed all over the country made a critical appraisal available evidence definition 10 suggestions regarding measures to be de-implemented. Strong were only when high-quality was available. The aim select low-value medical interventions, characterized by an unfavorable balance between potential benefits, harms, costs, which should discouraged in women with endometriosis. following agreed...
Abstract STUDY QUESTION Do extracellular vesicles (EVs) secreted by aneuploid human embryos possess a unique transcriptomic profile that elicits relevant response in decidualized primary endometrial stromal cells (dESCs)? SUMMARY ANSWER Aneuploid embryo-derived EVs contain transcripts of PPM1J, LINC00561, ANKRD34C, and TMED10 with differential abundance from euploid induce upregulation MUC1 transcript dESCs. WHAT IS KNOWN ALREADY We have previously reported IVF secrete can be internalized...
The evaluation of endometriosis in an adolescent girl is a challenging topic. initial stage the disease and limited diagnostic instrument appropriate for youth age its typical features can reduce ability gynecologist. At same time, missing prompt diagnosis delay beginning specific punctual management endometriosis, which could avoid postponed from 6 to 12 years, girls complaining dysmenorrhea. This article aimed answer all potential questions around adolescents starting clinical case looking...
The presence of endometriosis determines an inflammatory response locally. objective this validation study and systematic review was to assess systemic levels coagulation parameters in women with or without the disease. We conducted a retrospective analysis database prospectively collected from January 2017 February 2020 including n = 572 who underwent laparoscopic surgery for (cases, 324) other benign gynecologic diseases (controls, 248). Inflammatory markers were determined. An advanced...
Background In recent years, excisional surgery has been questioned as an ideal surgical approach for endometriomas because it is associated with potential removal of healthy ovarian tissue and loss follicles subsequent reduction reserve. The aim our study was to evaluate the benefits CO 2 laser vaporization through a clinical trial assessing postoperative changes in reserve indicated by antral follicle count (AFC) anti-Müllerian hormone (AMH). Materials Methods Fifteen patients undergoing...
BACKGROUND: Infertile women carrying ovarian endometriomas can be managed either with surgery or by in-vitro fertilization (IVF). The aim of this study was to compare responsiveness controlled stimulation (COS) in assisted reproduction techniques (ART) infertile small intact and those endometrioma cystectomy CO2 fiber laser ablation.METHODS: Retrospective case-control prospectively collected data including underwent ART for endometriosis-related infertility. group consisted undergoing...
BACKGROUND: Data about endometrioma ablation using energies with little thermal spread reported good results in terms of ovarian reserve and postoperative pregnancy rates. The aim the present study was to assess impact one step CO2 fiber laser vaporization for on subsequent controlled stimulation.METHODS: This prospective observational cohort included a consecutive series infertile patients who have undergone fibre treatment. primary endpoint number follicles per ovary growing during...
The surgical management of endometrioma is still a matter debate. Cystectomy, which recognized as the standard technique, seems to be associated with potential reduction in ovarian reserve due inadvertent removal and thermal damage healthy tissue. New ablative techniques reduced tissue penetration depth less spread surrounding parenchyma may represent viable alternative cystectomy. For these reasons, aim this manuscript demonstrate ablation capsule using CO2 fiber laser technique discuss...
The surgical management of endometrioma is still a matter debate. Cystectomy, which recognized as the standard technique, seems to be associated with potential reduction in ovarian reserve due inadvertent removal and thermal damage healthy tissue. New ablative techniques reduced tissue penetration depth less spread surrounding parenchyma may represent viable alternative cystectomy. For these reasons, aim this manuscript demonstrate ablation capsule using CO2 fiber laser technique discuss...
Abstract Study question Do EVs from human follicular fluid (FF-EVs), cervicovaginal (CVF-EVs), and endometrial stromal cells spent medium (ESCs-EVs) induce sperm capacitation enhance motility? Summary answer In humans, different female reproductive tracts actively contribute to maturation by inducing enhancing progressive motility. What is known already the body, represent crucial players in cell-to-cell communication. presence has been detected also male systems, specifically seminal,...