- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Aortic Disease and Treatment Approaches
- Vascular Procedures and Complications
- Cardiac Valve Diseases and Treatments
- Neuroscience and Neural Engineering
- Peripheral Artery Disease Management
- Cardiac pacing and defibrillation studies
- Cerebrovascular and Carotid Artery Diseases
- Renal and Vascular Pathologies
- Photoreceptor and optogenetics research
- Coronary Interventions and Diagnostics
- Abdominal vascular conditions and treatments
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Congenital Heart Disease Studies
- Coronary Artery Anomalies
- Acute Ischemic Stroke Management
- Gastrointestinal disorders and treatments
- Diabetic Foot Ulcer Assessment and Management
- Adrenal and Paraganglionic Tumors
- Neuroethics, Human Enhancement, Biomedical Innovations
- Cardiovascular and Diving-Related Complications
- Cardiovascular Conditions and Treatments
- Pain Management and Treatment
The University of Texas Southwestern Medical Center
2012-2024
The Ohio State University Wexner Medical Center
2024
Veterans Health Administration
2017-2023
George Washington University
2017-2021
Washington DC VA Medical Center
2019-2021
Southwestern Medical Center
2012-2021
George Washington University Hospital
2018-2021
Children's Medical Center
2012
Small animals support a wide range of pathological phenotypes and genotypes as versatile, affordable models for pathogenesis cardiovascular diseases exploration strategies in electrotherapy, gene therapy, optogenetics. Pacing tools such contexts are currently limited to tethered embodiments that constrain animal behaviors experimental designs. Here, we introduce highly miniaturized wireless energy-harvesting digital communication electronics thin, pacing platforms weighing 110 mg with...
The atrioventricular node (AVN) is a complex structure that performs variety of functions in the heart. AVN primarily an electrical gatekeeper between atria and ventricles introduces delay atrial ventricular excitation, allowing for efficient filling. composed several compartments safely transmit excitation from to via fast or slow pathways. There are many electrophysiological differences these pathways, including conduction time refractoriness, increase predisposition junction arrhythmias...
Abstract Recent developments in optophysiology techniques such as optogenetics have revolutionized the ability to actuate cell activity. Further combining and electrophysiology will integrate advantages from both optical electrical modalities yield enabling technologies that allow simultaneous monitoring of cellular activity response modulation, which are crucial for biomedical applications. However, multifunctional devices can deliver stimuli regions beneath electrodes perform sensing...
ObjectiveEndovascular repair of chronic dissecting aortoiliac aneurysms is challenging given the rigid septum, compressed true lumen, and target vessels frequently originating in false lumen. We have used transcatheter electrosurgical aortic septotomy (TEAS) prior to stent-graft implantation under intravascular ultrasound (IVUS) fusion guidance. The purpose this study assess outcomes TEAS during complex endovascular aneurysms.MethodsFrom 2021 2023, 17 patients underwent septotomy. primary...
Endovascular treatment in thoracic aortic diseases has increased use exponentially since Dake and colleagues first described the of a home-made transluminal endovascular graft on 13 patients with descending aneurysm at Stanford University early 1990s. Thoracic repair (TEVAR) was initially developed for therapy deemed unfit open surgery. Innovations endograft engineering design popularization techniques have transformed TEVAR to predominant choice elective repair. The number TEVARs performed...
Total endovascular repair of aortic arch aneurysms is feasible in select patients. This study aims to evaluate the feasibility and early outcomes total using 3-vessel company-manufactured devices (CMDs) physician-modified endo grafts (PMEGs).Patients unfit for open who underwent at a single institution from 2018 2021 were reviewed. Patients received either inner-branch CMDs or PMEGs. Three-vessel designs used incorporate innominate, left common carotid, subclavian arteries. The antegrade...
Altered autonomic balance is a hallmark of numerous cardiovascular diseases, including myocardial infarction (MI). Although device-based vagal stimulation cardioprotective during chronic disease, non-invasive approach to selectively stimulate the cardiac parasympathetic system immediately after an does not exist and desperately needed. Cardiac neurons (CVNs) in brainstem receive powerful excitation from population paraventricular nucleus (PVN) hypothalamus that co-release oxytocin (OXT)...
Objectives Widespread adoption of endovascular therapy for the treatment chronic limb-threatening ischemia has transformed field vascular surgery. In this modern era, we aimed to define where open surgical interventions are greatest benefit limb salvage. Methods Patients who underwent were identified in vascular-targeted lower extremity National Surgical Quality Improvement Program database (OPEN) and (ENDO) from 2011 2017. further stratified based on criteria (rest pain or tissue loss),...
Background: The Surgical Treatment for Ischemic Heart Failure (STICH) trial showed that surgical revascularization in ischemic cardiomyopathy (ICM) patients improves long-term mortality compared with medical treatment alone. This study examines how veterans ICM undergoing fare against without ICM; it also the outcomes veteran population. Methods: is a retrospective review of single-center database. From 2000 to 2018, 1,461 underwent isolated coronary artery bypass grafting (CABG)....
Abstract OBJECTIVES Factors such as more diffuse atherosclerosis, plaque instability and accelerated vascular calcification in patients with chronic end-stage renal disease (ESRD) can potentially present intraoperative challenges coronary artery bypass grafting (CABG) procedures. We evaluated whether ESRD experienced surgical strategy changes and/or graft revisions than normal function when undergoing CABG procedures according to a protocol for high-frequency ultrasound transit-time flow...
Objective: Heart disease is still the leading cause of death for both men and women in United States, rate cardiovascular veterans even higher than civilians. This study examines age-related outcomes undergoing cardiac surgeries at a single institution. Methods: We included all coronary artery bypass grafting (CABG) and/or valve surgery between 1997 to 2017 Veterans Affairs (VA) medical center. stratified this cohort into 4 age groups: ≤59 years old, 60–69 70–79 ≥80 old. Outcomes groups were...