A5011545660- Spinal Cord Injury Research
- Cerebral Palsy and Movement Disorders
- Stroke Rehabilitation and Recovery
- Heart Rate Variability and Autonomic Control
- Cardiovascular and exercise physiology
- Nerve Injury and Rehabilitation
- Cardiac Arrest and Resuscitation
- Physical Activity and Health
- Animal Nutrition and Physiology
- Sports injuries and prevention
- Neuroscience of respiration and sleep
- Muscle activation and electromyography studies
- Urinary Bladder and Prostate Research
- Prosthetics and Rehabilitation Robotics
- Pain Management and Treatment
- Pelvic floor disorders treatments
- Cannabis and Cannabinoid Research
- COVID-19 Clinical Research Studies
- Cardiovascular Effects of Exercise
- Long-Term Effects of COVID-19
- Mobile Health and mHealth Applications
- Obstructive Sleep Apnea Research
- Cardiovascular Health and Disease Prevention
- Spinal Dysraphism and Malformations
- Behavioral Health and Interventions
International Collaboration On Repair Discoveries
2018-2025
University of British Columbia
2018-2025
University of Birmingham
2020-2025
Royal Devon & Exeter NHS Foundation Trust
2024
Birkbeck, University of London
2022
NIHR Surgical Reconstruction and Microbiology Research Centre
2022
Pain and Rehabilitation Medicine
2020
University of Bath
2014-2019
GF Strong Rehabilitation Centre
2019
Vancouver Coastal Health
2019
Wearable physical activity monitors are growing in popularity and provide the opportunity for large numbers of public to self-monitor behaviours. The latest generation these devices feature multiple sensors, ostensibly similar or even superior advanced research instruments. However, little is known about accuracy their energy expenditure estimates. Here, we assessed performance against criterion measurements both controlled laboratory conditions (simulated activities daily living structured...
Spinal cord injury (SCI) leads to severe impairment in cardiovascular control, commonly manifested as a rapid, uncontrolled rise blood pressure triggered by peripheral stimuli-a condition called autonomic dysreflexia. The objective was demonstrate the translational potential of noninvasive transcutaneous stimulation (TCS) mitigating dysreflexia following SCI, using pre-clinical evidence and clinical case report. In rats with we show that TCS not only prevents instigation dysreflexia, but...
Despite obesity being highly prevalent in persons with spinal cord injury (SCI), our current understanding of the interactions between energy balance components, which may contribute to this, is limited. The primary aim this study identify intra-individual variability physical activity dimensions across days and suggest an appropriate monitoring time frame for these constructs adults SCI. secondary examine parameters regard intake dietary macronutrient composition. Participants [33 men women...
Purpose To assess the validity of two accelerometer devices, at different anatomical locations, for prediction physical activity energy expenditure (PAEE) in manual wheelchair users (MWUs). Methods Seventeen MWUs (36 ± 10 yrs, 72 11 kg) completed ten activities; resting, folding clothes, propulsion on a 1% gradient (3,4,5,6 and 7 km·hr-1) 4km·hr-1 (with an additional 8% body mass, 2% 3% gradient) motorised treadmill. GT3X+ GENEActiv accelerometers were worn right wrist (W) upper arm (UA)....
Abstract Spinal cord injury chronically alters cardiac structure and function is associated with increased odds for cardiovascular disease. Here, we investigate the consequences of spinal on acute-to-chronic continuum, contribution altered bulbospinal sympathetic control to decline in following injury. By combining experimental rat models prospective clinical studies, demonstrate that causes a rapid sustained reduction left ventricular contractile precedes structural changes. In rodents,...
Spinal cord injury (SCI) results in severe cardiovascular dysfunction due to the disruption of supraspinal control. Autonomic dysreflexia (AD), an uncontrolled rise blood pressure response peripheral stimuli including common bowel routine, digital anorectal stimulation (DARS), reduces quality life, and increases morbidity mortality. Recently, spinal (SCS) has emerged as a potential intervention mitigate unstable following SCI. The objective this case series was test real-time effect epidural...
This study aimed to assess the influence of anatomical placement an accelerometer on physical activity energy expenditure prediction in manual wheelchair users.Ten units (ActiGraph GT3X+) were attached a multiaxis shaker table and subjected sinusoidal oscillation procedure mechanical validity reliability. Fifteen users (mean ± SD: age, 36 11 yr; body mass, 70 12 kg) then completed five activities, including desk work propulsion (2, 4, 6, 8 km·h). Expired gases collected throughout. GT3X+...
Purpose Spinal cord injury (SCI) creates a complex pathology, characterized by low levels of habitual physical activity and an increased risk cardiometabolic disease. This study aimed to assess the effect moderate-intensity upper-body exercise training intervention on biomarkers component risks, adipose tissue metabolism, cardiorespiratory fitness in persons with SCI. Methods Twenty-one inactive men women chronic (>1 yr) SCI (all paraplegic injuries) 47 ± 8 yr age (mean SD) were randomly...
To assess the error in predicting physical activity energy expenditure (PAEE), using a multisensor device wheelchair users, and to examine efficacy of an individual heart rate calibration (IC) method.15 manual users (36±10 years, 72±11 kg) completed 10 activities: resting, folding clothes, propulsion on 1% gradient (3456 7 km/h) at 4 km/h (with additional 8% body mass, 2% 3% gradient) motorised treadmill. Criterion PAEE was measured computerised indirect calorimetry system. Participants wore...
ABSTRACT Purpose This study aimed to assess the accuracy of existing basal metabolic rate (BMR) prediction equations in men with chronic (>1 yr) spinal cord injury (SCI). The primary aim is develop new SCI population-specific BMR models, based on anthropometric, body composition, and/or demographic variables that are strongly associated BMR. Methods Thirty (paraplegic, n = 21, tetraplegic, 9) 35 ± 11 yr old (mean SD) participated this cross-sectional study. Criterion values were measured...
Background/Objectives To examine associations of different anthropometric measurements central adiposity to visceral adipose tissue (measured via multi-axial magnetic resonance imaging; MRI) and cardiometabolic disease risk factors in men with spinal cord injury (SCI). Additionally, determine population-specific seated/supine waist abdominal circumference cutoffs, which may identify at increased disease. Participants/Methods Twenty-two chronic SCI underwent MRI scans, along assessments...
Introduction Individuals with higher neurological levels of spinal cord injury (SCI) at or above the sixth thoracic segment (≥T6), exhibit impaired resting cardiovascular control and responses during upper-body exercise. Over time, predisposes individuals to lower cardiorespiratory fitness thus a greater risk for disease mortality. Non-invasive transcutaneous stimulation (TSCS) has been shown modulate rest in SCI, yet its effectiveness enhance exercise performance acutely, promote superior...