A5043979136- Skin and Cellular Biology Research
- SARS-CoV-2 and COVID-19 Research
- Long-Term Effects of COVID-19
- Olfactory and Sensory Function Studies
- Tumors and Oncological Cases
- Teratomas and Epidermoid Cysts
- Head and Neck Surgical Oncology
- Genetic and rare skin diseases.
- Hedgehog Signaling Pathway Studies
KU Leuven
2025
AZ Sint-Jan
2021-2023
Highlights•A postmortem bedside surgical procedure was developed for COVID-19 and control patients•Ciliated cells are the main target cell type SARS-CoV-2 in respiratory mucosa•Sustentacular (non-neuronal) olfactory mucosa•No evidence infection of sensory neurons or bulb parenchymaSummaryAnosmia, loss smell, is a common often sole symptom COVID-19. The onset sequence pathobiological events leading to dysfunction remains obscure. Here, we have harvest endoscopically samples mucosae whole...
Epidermal nevus syndrome (ENS) comprises a heterogeneous group of neurocutaneous syndromes associated with the presence epidermal nevi and variable extracutaneous manifestations. Postzygotic activating HRAS pathogenic variants were previously identified in sebaceous (NS), keratinocytic (KEN), different ENS, including Schimmelpenning-Feuerstein-Mims cutaneous-skeletal-hypophosphatasia (CSHS). Skeletal involvement HRAS-related ENS ranges from localized bone dysplasia association KEN to...