A5028125849- Geology and Paleoclimatology Research
- Paleontology and Stratigraphy of Fossils
- Luminescence and Fluorescent Materials
- Organic Light-Emitting Diodes Research
- Hydrocarbon exploration and reservoir analysis
- Geochemistry and Elemental Analysis
- Geological and Geophysical Studies
- Pleistocene-Era Hominins and Archaeology
- CRISPR and Genetic Engineering
- Power Systems and Renewable Energy
- RNA and protein synthesis mechanisms
- Organic Electronics and Photovoltaics
- Cancer, Hypoxia, and Metabolism
- Geological formations and processes
- RNA Research and Splicing
- Ubiquitin and proteasome pathways
- Geological and Geochemical Analysis
- Essential Oils and Antimicrobial Activity
- Power Systems and Technologies
- Sirtuins and Resveratrol in Medicine
- Robot Manipulation and Learning
- Integrated Energy Systems Optimization
- Nanocluster Synthesis and Applications
- Evolution and Paleontology Studies
- Granular flow and fluidized beds
Tianjin University of Science and Technology
2023-2024
Shanghai Power Equipment Research Institute
2024
Shaanxi University of Chinese Medicine
2023-2024
Stanford University
2021-2024
Air Force Medical University
2024
Beijing University of Chemical Technology
2024
University of Chinese Academy of Sciences
2020-2023
Chinese Academy of Sciences
2020-2023
Institute of Geology and Geophysics
2020-2023
Arc Research Institute
2023
Abstract Background Oral squamous cell carcinoma (OSCC), the predominant malignancy of oral cavity, is characterized by high incidence and low survival rates. Emerging evidence suggests a link between circadian rhythm disruptions cancer development. The gene TIMELESS, known for its specific expression in various tumors, has not been extensively studied context OSCC. This study aims to explore influence TIMELESS on OSCC, focusing growth metabolic alterations. Methods We analyzed OSCC using...
Spatial separation of the TADF sensitizer and fluorescent emitter improve energy transfer efficiency by suppressing loss further enhance electroluminescent performance.
Granular materials are critical to many natural and industrial processes, yet the chaotic flow behavior makes granular dynamics difficult understand, model, control, causing difficulties for disaster mitigation as well scale-up optimization of devices. Hydrodynamic instabilities in externally excited grains often resemble those fluids, but have different underlying mechanisms, these provide a pathway understand geological patterns control flows industry. particles subject vibration been...
Technologies for precisely inserting large DNA sequences into the genome are critical diverse research and therapeutic applications. Large serine recombinases (LSRs) can mediate direct, site-specific genomic integration of multi-kilobase without a pre-installed landing pad, but current approaches suffer from low insertion rates high off-target activity. Here, we present comprehensive engineering roadmap joint optimization recombination efficiency specificity. We combined directed evolution,...
The Eocene is the initial stage of Cenozoic global cooling. Compared with abundant marine records, continental records are scarce. Throughout Eocene, a series continuous deposition gypsum and volcanic tuff-bearing red clastic sediments have developed in Nangqian Basin (NB). In this work, representative were collected from NB, lipid biomarkers compound-specific carbon isotopes n -alkanes analyzed. Based on robust paleomagnetic age–depth model, early to late isotopic compositions (δ 13 C 23 δ...
A defining goal of synthetic biology is to develop biomaterials with superior performance and versatility. Here we introduce a purely genetically encoded self-assembling biopolymer based on the SpyTag–SpyCatcher chemistry. We show application this polymer for highly efficient uranyl binding extraction from aqueous solutions, by embedding two functional modules—the superuranyl protein monomeric streptavidin—to via genetic fusion. further provide modeling strategy predicting polymer's physical...
Abstract Transcriptome engineering technologies that can effectively and precisely perturb mammalian RNAs are needed to accelerate biological discovery RNA therapeutics. However, the broad utility of programmable CRISPR-Cas13 ribonucleases has been hampered by an incomplete understanding design rules governing guide activity as well cellular toxicity resulting from off-target or collateral cleavage. Here, we sought characterize develop Cas13d systems for efficient specific knockdown with low...
Abstract Although previous studies have shown that the paleoenvironment and geological processes contributed to organic matter accumulation (OMA) carbon isotope excursions (CIEs) during late Ordovician–early Silurian, dominated controlling factor for OMA origins of CIEs still remains unclear due complex interaction between various paleoenvironmental factors processes. Therefore, based on elemental geochemistry Wufeng–Longmaxi Formation shales in upper Yangtze Platform, we analyzed Silurian...
Hydroclimate evolution history and changes in the Tibetan Plateau play significant roles depicting paleoclimate evaluating climatic conditions coming future. However, interaction of westerlies Asian monsoon complicates our understanding mechanism climate variation over Plateau. In this study, we assessed Hurleg Lake, which was previously located convergence area East westerly wind. We first reconstructed based on fined-grained authigenic carbonate δ 18 O (δ carb ), plant-derived proxies C/N,...
Marine–continental transitional strata were widely developed in the Ordos Basin Upper Carboniferous - Lower Permian. The Taiyuan Shanxi Formation possesses promising shale gas exploration layers. Shale samples from two drilling wells of Shanxi-Taiyuan Shilou and Xixian, Basin, investigated to study their carbon–sulfur contents distribution characteristics organic components using carbon/sulfur analyzer chromatography–mass spectroscopy. Using results total carbon analyses, Rock-Eval...
In order to improve the operation efficiency of power system and reduce performance system, a new hierarchical optimal scheduling method regional integrated energy based on multi-objective particle swarm optimization algorithm is proposed in this paper. Aiming at economic goal dispatching, dispatching objective function constructed, constraints are constructed from three aspects: Branch flow constraint, upper grid injection gas turbine. The used optimize model, build lower models, complete...
The Ediacaran–Cambrian period witnessed episodic extinctions, oxygenation of seawaters, Cambrian explosions, and tectonic events. However, compared with the various high-resolution geochemical records early–middle Ediacaran Cambrian, available record latest (551–542 Ma) is scarce (especially strontium isotope elements), which leads to ambiguous interpretation paleoenvironment Ediacaran. Therefore, we conducted measurements isotopes elemental content a continuous series carbonate samples from...
The change of temperature, humidity and moisture content (MC) will lead to the mechanical properties molded fiber products (MFP). However, it is difficult decouple effects MC on MFP, predict MFP during use. In this study, laws mechanism with ambient were studied. results showed that direct effect temperature (20−70 °C) was insignificant, mainly changed by MC. related humidity, relationship between three could be described modified Guggenheim-Anderson-de Boer (GAB) model °C 30%−90% relative...
In 6G mobile communication technology, accurately perceiving channel state information can significantly improve performance, enabling spatial multiplexing and more accurate beamforming. Intelligent holographic radio imaging technology precisely perceive the electromagnetic space of users in complex environments, obtaining interferograms with extremely high resolution fine spectral resolution. Reconstruction K-space yield such as central frequency azimuth incident signals. This paper...