- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Drug Solubulity and Delivery Systems
- Bone health and treatments
- Nanoplatforms for cancer theranostics
- Advancements in Transdermal Drug Delivery
- Extracellular vesicles in disease
- Advanced biosensing and bioanalysis techniques
- Hydrogels: synthesis, properties, applications
- Protein purification and stability
- Pharmaceutical studies and practices
- Electrospun Nanofibers in Biomedical Applications
- Bone Metabolism and Diseases
- SARS-CoV-2 and COVID-19 Research
- Immunotherapy and Immune Responses
- Antimicrobial Peptides and Activities
- Crystallization and Solubility Studies
- Boron Compounds in Chemistry
- Collagen: Extraction and Characterization
- Ocular Surface and Contact Lens
- MicroRNA in disease regulation
- Olfactory and Sensory Function Studies
- Lipid Membrane Structure and Behavior
- Biochemical Analysis and Sensing Techniques
National Institute of Pharmaceutical Education and Research
2021-2024
Government of India
2021-2023
Implantable drug delivery systems advocate a wide array of potential benefits, including effective administration drugs at lower concentrations and fewer side-effects whilst increasing patient compliance. Amongst several polymers used for fabricating implants, biopolymers such as polysaccharides are known modulating attributes desired. The review describes the strategies employed development polysaccharide-based implants. A comprehensive understanding polysaccharide starch, cellulose,...
Receptor-targeted drug delivery has been extensively explored for active targeting of therapeutic moiety in cancer treatment. In this review, we discuss the receptors that are overexpressed on tumor cells and have potential to be targeted by nanocarrier systems We also highlight different types ligands researchers explored. Our discussion covers various modalities, including small molecules, aptamers, peptides, antibodies, cell-based strategies, focuses clinical developments. Additionally,...
Immunotherapy has emerged as a powerful approach in treating various diseases, yet its success often hinges on the efficacy of adjuvants, agents that boost immune responses to therapeutic targets. Traditional adjuvants have offered foundational support but may fall short achieving specificity and potency required for advanced therapies. This review highlights new generation poised address these limitations. We explore range innovative agents, including non-inflammatory nucleic acid bacterial...
Bone-specific functionalization strategies on liposomes are promising approaches to delivering the drug in osteoporotic conditions. This approach delivers bone surface specifically, reduces dose and off-target effects of drug, thereby toxicity drug. The purpose current research work was fabricate bone-specific peptide conjugated pegylated nanoliposomes deliver anabolic its physicochemical evaluations. For this, a (SDSSD) synthesized, synthesized with linker (DSPE-PEG2000-COOH) obtain...
Epilepsy is one of the major neurological disorders, affecting about 50 million people globally. Oral, intravenous, and rectal delivery systems are available for management epileptic seizures. However, intranasal serves beneficial delivering anti-epileptic drugs owing to advantages it offers.
Screening of critical variables, including formulation and process in the development various dosage forms facilitates identification most influencing parameters, which modulate responses, thereby helping building strong quality target product profile.The objective present work was to screen out influential variables for an anabolic peptide encapsulated lipid nanovesicles (PTH-LNVs).PTH-LNVs were prepared by ethanol injection method. Taguchi standard orthogonal array L8 design employed...
The objective of the present work was to develop PTH (1-34)-loaded stealth nanoliposomes (PTH-LPs) by employing use Quality Design (QbD) approach. Risk identification carried out using Ishikawa fishbone diagram. PTH-LPs were optimized Box Behnken Design, a type response surface methodology examine effect independent variables on dependent such as particle size and percentage entrapment efficiency (%EE). space generated for reduce interbatch variability during formulation development process....