Somesh Gupta

ORCID: 0000-0003-3015-8602
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About
Contact & Profiles
Research Areas
  • melanin and skin pigmentation
  • Dermatologic Treatments and Research
  • Herpesvirus Infections and Treatments
  • Hair Growth and Disorders
  • Reproductive tract infections research
  • Cutaneous Melanoma Detection and Management
  • Genetic and rare skin diseases.
  • Skin Protection and Aging
  • Autoimmune Bullous Skin Diseases
  • Nail Diseases and Treatments
  • Medicine and Dermatology Studies History
  • Syphilis Diagnosis and Treatment
  • Nonmelanoma Skin Cancer Studies
  • Genital Health and Disease
  • Cancer and Skin Lesions
  • Cell Adhesion Molecules Research
  • Cutaneous lymphoproliferative disorders research
  • Body Contouring and Surgery
  • Autoimmune and Inflammatory Disorders
  • Fungal Infections and Studies
  • Cervical Cancer and HPV Research
  • Facial Rejuvenation and Surgery Techniques
  • Dermatology and Skin Diseases
  • Parvovirus B19 Infection Studies
  • Atherosclerosis and Cardiovascular Diseases

All India Institute of Medical Sciences
2016-2025

All India Institute of Medical Sciences Raipur
2013-2024

All India Institute of Medical Sciences Bhopal
2013-2024

Axis Multispecialty Hospital
2024

Creative Commons
2022-2023

Institute of Liver and Biliary Sciences
2023

Saint Luke's Hospital
2023

Paras Hospitals
2022

Maharishi Markandeshwar University, Mullana
2021

Institute of Medical Sciences
1999-2021

The treatment of vitiligo can be challenging. Up-to-date agreed consensus recommendations on the use topical and systemic therapies to facilitate clinical management are currently lacking.To develop internationally agreed-upon expert-based for vitiligo.In this statement, a consortium 42 international experts four patient representatives participated in different online live meetings strategy vitiligo. At least two summarized evidence topics included algorithms. A survey was then given core...

10.1111/jdv.19450 article EN cc-by-nc Journal of the European Academy of Dermatology and Venereology 2023-09-15

Data Privacy has increasingly become a matter of concern in the era large public digital respositories data. This is particularly true healthcare where data can be misused if traced back to patients, and brings with itself myriad possibilities. Bring custodians data, as well being at helm disigning studies products that potentially benefit products, professionals often find themselves unsure about ethical legal constraints undelie sharing. In this review we touch upon concerns, leal...

10.4103/idoj.idoj_543_23 article EN cc-by-nc-sa Indian Dermatology Online Journal 2023-10-27

The treatment of vitiligo can be challenging and depends on several factors such as the subtype, disease activity, extent, goals. Vitiligo usually requires a long-term approach. To improve management worldwide, clear up-to-date guide based international consensus with uniform stepwise recommendations is needed.To reach an nomenclature to develop algorithm for diagnosis, assessment, vitiligo.In this statement, consortium 42 experts four patient representatives participated in online live...

10.1111/jdv.19451 article EN cc-by-nc Journal of the European Academy of Dermatology and Venereology 2023-09-25

Current noncultured cell-based transplantation therapies for vitiligo largely involve shave skin biopsy preparation of melanocyte suspension. As the overall proportion melanocytes is low in epidermis, these techniques require basal cell layer enrichment, which adds additional steps. We tried follicular unit extraction (FUE) to harvest hair follicles as a source melanocytes.To evaluate efficacy novel surgical method vitiligo: extracted outer root sheath (ORS) suspension...

10.1111/j.1365-2133.2011.10234.x article EN British Journal of Dermatology 2011-01-28

Scar formation is an inevitable consequence of wound healing from either a traumatic or surgical intervention. The aesthetic appearance scar the most important criteria to judge outcome. An understanding anatomy and along with experience, meticulous planning technique can reduce complications improve revision does not erase but helps make it less noticeable more acceptable. Both non-surgical techniques, used alone in combination be for revising scar. In surgeon should decide on when act type...

10.4103/0974-2077.129959 article EN Journal of Cutaneous and Aesthetic Surgery 2014-01-01

Abstract Background The integration of machine learning algorithms in decision support tools for physicians is gaining popularity. These can tackle the disparities healthcare access as technology be implemented on smartphones. We present first, large‐scale study patients with skin colour, which feasibility a novel mobile health application (mHealth app) was investigated actual clinical workflows. Objective To develop mHealth app to diagnose 40 common diseases and test it settings. Methods A...

10.1111/jdv.16967 article EN Journal of the European Academy of Dermatology and Venereology 2020-09-29

Suction blister epidermal grafting is a useful modality of treatment resistant and stable vitiligo; however, it requires expensive heavy suction apparatus. This study an attempt to develop cheap small apparatus which can be assembled in the physician's own office.The method was tried 22 vitiligo/leukoderma patients. The consisted cylindrical funnel connected with three-way tap, given by 50-mL syringe. pressure inside cup retained changing position lock tap. measured connecting tap vacuum...

10.1046/j.1365-4362.1999.00702.x article EN International Journal of Dermatology 1999-04-01

Intralesional immunotherapy with skin test antigens and vaccines has been found to be effective in the management of genital extragenital warts.To evaluate efficacy safety intralesional Mycobacterium w (Mw) vaccine monotherapy for treatment ano-genital warts.Ten patients clinically diagnosed have external warts, including three giant warts (Buschke Löwenstein tumour), were included this open-label pilot study. Two human immunodeficiency virus seropositive, one was on iatrogenic...

10.1111/j.1468-3083.2008.02719.x article EN Journal of the European Academy of Dermatology and Venereology 2008-05-15

Vitiligo is an autoimmune depigmentation disease, and defects in regulatory T cells (Tregs) have been proposed the pathogenesis of generalized vitiligo (GV). However, role programmed cell death (PD)1(+) Tregs has not studied.To investigate status Tregs, PD1(+) associated parameters active GV (aGV) during first episode disease attack to establish clinical correlation.The percentages circulating CD3(+) CD4(+) were evaluated 50 patients with aGV 51 controls. Expression levels FOXP3, TGFB1,...

10.1111/bjd.13511 article EN British Journal of Dermatology 2014-11-06

Stability is considered the most important parameter before performing any melanocyte transplantation procedure in vitiligo; however, current criteria rely on history given by patients.This study was undertaken to determine clinical, biochemical and immunological factors determining stability of disease patients with generalized vitiligo facilitate better patient selection for understand mechanisms activity.Thirty-three < 10% body surface area involved were allocated three clinical groups:...

10.1111/j.1365-2133.2012.10886.x article EN British Journal of Dermatology 2012-02-13

Noncultured epidermal cell suspension (NCES) is an effective surgical modality for stable vitiligo which involves transplantation of the basal layer cells onto dermabraded vitiliginous patch. Platelet-rich plasma (PRP) has growth factors may stimulate melanocyte migration and proliferation keratinocytes fibroblasts. The objective this study was to compare extent repigmentation achieved by NCES suspended in PRP with that phosphate buffered saline (PBS).Twenty-one patients at least two lesions...

10.1111/ijd.14286 article EN International Journal of Dermatology 2018-12-02

Bacterial vaginosis (BV) is a common clinical manifestation of perturbed vaginal ecology associated with adverse sexual and reproductive health outcomes if left untreated. The existing diagnostic modalities are either cumbersome or require skilled expertise, warranting alternate tests. Application machine-learning tools to heterogeneous high-dimensional multi-omics datasets finds promising potential in data integration may aid biomarker discovery.

10.1111/jdv.19805 article EN Journal of the European Academy of Dermatology and Venereology 2024-01-29

IMPORTANCEIntralesional antigen therapy has been used in the treatment of anogenital warts (AGWs), but it not compared with existing therapies.Evidence its efficacy is strong.OBJECTIVE To compare and safety intralesional Mycobacterium w (Mw) vaccine that imiquimod, 5%, cream AGWs, as well changes human papillomavirus (HPV)-6 HPV-11 viral loads. DESIGN, SETTING, AND PARTICIPANTSA double-blind randomized clinical trial was conducted New Delhi, India, between February 2009 July 2012 included a...

10.1001/jamadermatol.2014.794 article EN JAMA Dermatology 2014-08-07

Stigma refers to socially undesirable attributes of individuals or groups, associated with isolation, rejection, and discrimination. is an essential contributor in the causal web sexually transmitted infections (STIs) that flourish within global context inequities STIs: social class, race/ethnicity, immigration status, gender, gender expression, sexual orientation [[1]Starrs A.M. Ezeh A.C. Barker G. et al.Accelerate progress—sexual reproductive health rights for all: report Guttmacher–...

10.1016/j.eclinm.2021.100764 article EN cc-by-nc-nd EClinicalMedicine 2021-02-24
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