A5041443604- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- Advanced Sensor and Energy Harvesting Materials
- Rheology and Fluid Dynamics Studies
- Tissue Engineering and Regenerative Medicine
- Supramolecular Chemistry and Complexes
- Polymer crystallization and properties
- Advanced Polymer Synthesis and Characterization
- biodegradable polymer synthesis and properties
- Electrohydrodynamics and Fluid Dynamics
- Silicone and Siloxane Chemistry
- Supercapacitor Materials and Fabrication
- Supramolecular Self-Assembly in Materials
- Advancements in Photolithography Techniques
- Silk-based biomaterials and applications
- Microfluidic and Capillary Electrophoresis Applications
- Polymer Foaming and Composites
- Polymer Nanocomposites and Properties
- Conducting polymers and applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Hydrogels: synthesis, properties, applications
- Nanofabrication and Lithography Techniques
- Advanced optical system design
- Graphene and Nanomaterials Applications
- Surface Modification and Superhydrophobicity
Institut de Chimie
2015-2025
Université de Strasbourg
2015-2025
Centre National de la Recherche Scientifique
2015-2025
Institut de Chimie et Procédés pour l'Energie, l'Environnement et la Santé
2015-2025
Institut de Physique et Chimie des Matériaux de Strasbourg
2008-2022
Inserm
2022
Département Santé des Plantes et Environnement
2017-2020
Institut Européen de Chimie et Biologie
2013-2017
École Normale Supérieure - PSL
2002-2010
Laboratoire d'Ingénierie Circulation Transports
2010
Many works focus on the use of polyesters such as poly(lactic acid) (PLA) to produce nanofibrous scaffolds for cardiac tissue engineering. However, are hydrophobic and difficult functionalize. Here, we show that adding 30% poly(glycerol sebacate) (PGS) elastomer within PLA leads PLA:PGS with improved biological properties, depending processing parameters. Two categories fibers were produced by blend electrospinning, diameters 600 1300 nm. The resulting cured at 90 or 120 °C achieve two...
Topological polymer networks with sliding cross-link points, the "sliding gels" (also called slide-ring gels), are a new class of supramolecular based on intermolecularly cross-linked α-cyclodextrins/poly(ethylene glycol) polyrotaxane precursors. The points such not fixed but can slide along template chain polyrotaxanes. main parameters governing gel properties number cyclodextrins per polyrotaxane, cross-linking density, and nature swelling solvent. Small-angle neutron scattering,...
Bioactive implants intended for rapid, robust, and durable bone tissue regeneration are presented. The based on nanofibrous 3D-scaffolds of bioresorbable poly-ϵ-caprolactone mimicking the fibrillar architecture matrix. Layer-by-layer nanoimmobilization growth factor BMP-2 in association with chitosan (CHI) or poly-L-lysine over nanofibers is described. osteogenetic potential scaffolds coated layers CHI demonstrated vitro, vivo mouse calvaria, through enhanced osteopontin gene expression...
ABSTRACT Electrospun nanocomposites of poly(ε‐caprolactone) (PCL) incorporated with PCL‐grafted cellulose nanocrystals (PCL ‐g‐ CNC) were produced. PCL chains grafted from (CNC) surface by ring‐opening polymerization. Grafting was confirmed infrared spectroscopy (FTIR) and thermogravimetric analyses (TGA). The resulting CNC then into a matrix at various loadings. Homogeneous nanofibers average diameter decreasing the addition observed scanning electron microscopy (SEM). domains visualized...
This study reports the development of elastomeric mesoporous polyurethane (PU) membranes for bioartificial pancreas applications in type 1 diabetes treatment. The are designed to exhibit semi-permeable properties, enabling insulin diffusion while restricting larger immune molecules, such as immunoglobulin G (IgG). Although electrospinning is a widely used technique fabricating porous controlled drug release, it typically results an average pore size on order few micrometers, which two orders...
This work focuses on the synthesis of polyrotaxanes with high molecular weight template poly(ethylene glycol) PEG (20 kg mol) having various and well-defined amounts α-cyclodextrins (α-CD) per chain from 3 up to 125. is complexation degree polyrotaxane defined be average number cyclodextrin molecules chain. The usual route has been used for values , while sparsely complexed have synthesized an original one pot in water. Furthermore, a systematic study was carried out understand control as...
Electrospinning usually results in the formation of scaffolds that are a few hundred microns thickness with pore sizes micron range. However some applications, such as tissue engineering, necessitate fabrication cm-thick nanofibrous large allow for cell infiltration. Here, we demonstrate first time production bioresorbable poly(ε-caprolactone) foams using electrospinning technique. These were obtained through dynamic self-assembly electrospun nanofibers into honeycomb patterns, which...
We present here for the first time a simple method micropatterning nonwoven composite membranes. The approach is based on simultaneous electrospraying of microparticles and electrospinning nanofibers from different polymer solution feeds (polyethylene glycol poly(D,L-lactide)) common support. mechanism self-organization between fibers particles into hierarchical honeycomb-like structures, as well evolution later function thickness composite, investigated. demonstrate that aggregates...
Hierarchical carbon fibers/carbon nanofibers composites, with high effective surface areas and controlled macroscopic shapes, were successfully synthesized through a combination of electrospinning chemical vapour deposition.
In this article, normal stresses and shear in oscillatory flow are measured at small large deformation amplitudes. New material parameters then introduced based on Fourier transform rheology stress decomposition analysis of measurements. Furthermore, uniaxial extensional measurements performed compared to simulation results using the molecular function model. Different behaviors were observed for polyethylene polypropylene type blends, which believed arise from different types long-chain...
The elaboration of biomimetic materials inspired from the specific structure native bone is one main goal tissue engineering approaches. To offer most appropriate environment for reconstruction, we combined electrospinning and electrospraying to elaborate an innovative scaffold composed alternating layers polycaprolactone (PCL) hydroxyapatite (HA). In our approach, electrospun PCL was shaped into a honeycomb-like with inner diameter 160 μm, capable providing cells 3D while ensuring material...
Fourier transform rheology (FTR) consists of analyzing the frequency spectrum nonlinear torque response obtained during large-amplitude oscillatory shear. In present work, analysis has been carried out in whole complex space and was especially focused on study third harmonic I*3/I1 (= I*(3ω1)/I1, where I1 is intensity at fundamental ω1), I3/I1 |I*3/I1|), phase shift Φ3 I*3/I1. The accuracy FTR to characterize architecture linear, sparsely, densely branched polyethylene regarding number...
Abstract A macroscopic composite consisting of nitrogen‐doped carbon fibers (N@CFs) was synthesized by electrospinning. The as‐prepared N@CF material further applied as a metal‐free catalyst in the catalytic oxidation H 2 S to sulfur, which is one most important purification processes for raw chemical resources (that is, biogas, natural gas, and petrochemical compounds). catalyst, after carbonization step at T =800 °C, exhibits high stable desulfurization activity more than 100 h testing...