A5064757021- Genetic Associations and Epidemiology
- RNA modifications and cancer
- Genomic variations and chromosomal abnormalities
- Health, Environment, Cognitive Aging
- Endoplasmic Reticulum Stress and Disease
- Pancreatic function and diabetes
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Metabolism, Diabetes, and Cancer
- Cancer-related molecular mechanisms research
- Physiological and biochemical adaptations
- Peroxisome Proliferator-Activated Receptors
- Traditional Chinese Medicine Studies
- Genetic Syndromes and Imprinting
- Adrenal and Paraganglionic Tumors
- Adipokines, Inflammation, and Metabolic Diseases
- Marine Biology and Environmental Chemistry
- RNA Research and Splicing
- Kruppel-like factors research
- Medical and Biological Sciences
- Pituitary Gland Disorders and Treatments
- Marine animal studies overview
Gifu University
2024
St. Marianna University School of Medicine
2007-2012
RIKEN Center for Integrative Medical Sciences
2009
OBJECTIVE—Recently, several genes have been shown to be associated with an increased risk of type 2 diabetes by genome-wide association studies in white populations. To further investigate the involvement these polymorphisms conferring susceptibility diabetes, we examined 14 single nucleotide (SNPs) within 11 candidate loci a Japanese population. RESEARCH DESIGN AND METHODS—We analyzed SNPs (rs4402960 IGF2BP2, rs10811661 CDKN2A/B, rs1111875 and rs7923837 HHEX, rs13266634 SLC30A8, rs1113132...
To identify a novel susceptibility locus for type 2 diabetes, we performed an imputation-based, genome-wide association study (GWAS) in Japanese population using newly obtained imputed-genotype data 229 890 single-nucleotide polymorphisms (SNPs) estimated from previously reported, directly genotyped GWAS the same samples (stage 1: 4470 diabetes versus 3071 controls). We 43 new SNPs with P-values of <10(-4) part stage-1 (2692 controls), and associations validated were evaluated another 11 139...
Molecular genetic analyses are effective in revealing the origin, kinship, and diversity of zoo animals. In this study, we carried out characterization captive founder individuals South American fur seal (Arctocephalus australis) Japanese zoos aquariums based on mitochondrial sequences nuclear microsatellite loci. DNA analysis, haplotype nucleotide overall population were 0.8949 0.0119, respectively. Microsatellite analysis revealed that observed heterozygosity within was 0.722. addition,...