Gezi Chen

ORCID: 0000-0003-3040-0825
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About
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Research Areas
  • Reproductive System and Pregnancy
  • Anesthesia and Sedative Agents
  • Circular RNAs in diseases
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Cancer-related molecular mechanisms research
  • Cardiac, Anesthesia and Surgical Outcomes
  • Antibiotics Pharmacokinetics and Efficacy
  • Birth, Development, and Health
  • Neuroendocrine Tumor Research Advances
  • Epilepsy research and treatment
  • Assisted Reproductive Technology and Twin Pregnancy
  • Enhanced Recovery After Surgery
  • Wnt/β-catenin signaling in development and cancer
  • Liver Disease Diagnosis and Treatment
  • Ultrasound in Clinical Applications
  • Systemic Sclerosis and Related Diseases
  • Pregnancy and preeclampsia studies
  • Cancer Risks and Factors
  • Endometriosis Research and Treatment
  • Venous Thromboembolism Diagnosis and Management

First Affiliated Hospital of Zhengzhou University
2017-2024

A receptive endometrium is required in a successful embryo implantation. The ubiquitination-induced β-catenin degradation related to the implantation failure.This study aimed elucidate whether miR-23a-3p regulates endometrial receptivity via modulation of ubiquitination.The expressions and CUL3 were detected epithelial cells (EECs) isolated from pregnant mice hormone-induced EEC-like Ishikawa cells. ubiquitination experiment was performed explore effect on level. trophoblast attachment by...

10.1530/jme-20-0053 article EN Journal of Molecular Endocrinology 2020-06-26

Acute pulmonary embolism (APE) can be life-threatening. Early detection is even more difficult for patients under general anesthesia as common symptoms are not available and the pathophysiological course of intra-operative APE influenced by procedures surgery anesthesia, which makes a distinctive group. We report case during orthopedic anesthesia. A 64-year-old female with atrial fibrillation surgical history varicosity underwent total right hip replacement No arterial or deep vein...

10.1186/s12871-017-0360-0 article EN cc-by BMC Anesthesiology 2017-05-26

To determine whether ABCB1 gene polymorphisms affect the time course of action rocuronium in Chinese patients.This study included 105 unrelated patients undergoing general anesthesia with propofol, fentanyl, and rocuronium. Neuromuscular monitoring was performed calibrated acceleromyography. Patients were allowed to recover spontaneously from neuromuscular block. The interval between first maximum depression train four (TOF) spontaneous recovery TOF ratio 0.25/0.7/0.8/0.9 recorded. Sequenom...

10.5414/cp202547 article EN International Journal of Clinical Pharmacology and Therapeutics 2016-04-18

Objective This study aimed to evaluate potential predictors for recovery time in pregnant patients with moderate severe ovarian hyperstimulation syndrome (OHSS). Methods A total of 424 OHSS who underwent vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) were retrospectively identified. The clinical features and laboratory findings within 24 h after admission collected. Treatment was carried out according standard procedures, including fluid replacement therapy, human albumin,...

10.3389/fendo.2022.870008 article EN cc-by Frontiers in Endocrinology 2022-06-15

Abstract Backgroud: To evaluate potential predictors for recovery time in pregnant patients with moderate to severe ovarian hyperstimulation syndrome. Methods: A total of 424 OHSS underwent vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) were retrospectively identified. The clinical features and laboratory findings within 24 hours after admission collected. Treatment was carried out according standard procedure including fluid replacement therapy, human albumin, aspirin, low...

10.21203/rs.3.rs-1292102/v1 preprint EN cc-by Research Square (Research Square) 2022-01-28

Abstract Background Impaired endometrial receptivity is supposed to be a major element leading recurrent implantation failure (RIF). Numerous studies have identified that the lncRNAs-miRNAs-mRNAs regulation network functions in generation of receptive uterus. Long non-coding RNAs could act as competing endogenous pathogenesis RIF. However, our understanding underlying mechanism still limited. Results Based on RNA-Seq results, 617 DEmRNAs, 69 DElncRNAs and 107 DEmiRNAs were RIF group compared...

10.21203/rs.3.rs-1013014/v2 preprint EN cc-by Research Square (Research Square) 2021-11-15

Abstract Background: Impaired endometrial receptivity is supposed to be a major element leading recurrent implantation failure (RIF). Numerous studies have identified that the lncRNAs-miRNAs-mRNAs regulation network functions in generation of receptive uterus. Long non-coding RNAs could act as competing endogenous pathogenesis RIF. However, our understanding underlying mechanism still limited. Results: Based on RNA-Seq results, 617 DEmRNAs, 69 DElncRNAs and 107 DEmiRNAs were RIF group...

10.21203/rs.3.rs-1013014/v1 preprint EN cc-by Research Square (Research Square) 2021-10-28
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