A5050679910- Carbon and Quantum Dots Applications
- Essential Oils and Antimicrobial Activity
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Phytochemical compounds biological activities
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Piperaceae Chemical and Biological Studies
- Fungal Biology and Applications
- Heavy Metal Exposure and Toxicity
- Advanced biosensing and bioanalysis techniques
- Advancements in Transdermal Drug Delivery
- Microbial Natural Products and Biosynthesis
- Medicinal Plants and Neuroprotection
- Phytochemicals and Antioxidant Activities
- Pharmacological Effects of Natural Compounds
- Bioinformatics and Genomic Networks
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
- Selenium in Biological Systems
- Advanced Drug Delivery Systems
- Pharmacology and Nanomedicine Research
- Allelopathy and phytotoxic interactions
- Protein purification and stability
- Drug Solubulity and Delivery Systems
Indian Institute of Technology BHU
2020-2025
Banaras Hindu University
2020-2025
University of Toronto
2025
Nowadays, nanotechnology is extensively employed in the medical profession. In this study, we used aqueous extract of bark Mitragyna parvifolia to synthesize silver nanoparticles (AgNPs) by microwave-assisted green synthesis. The synthesis AgNPs was confirmed visual color change brown and characteristic surface plasmon resonance peak at 432 nm. hydrodynamic diameter 171.81 nm having a zeta potential −24.14 mV; Fourier Transmission Infrared Spectroscopy presence different functional groups on...
Abstract Background Breast carcinoma (BC) and lung (LC) have the highest incidence mortality rates worldwide. In prior work, studied sample hub targets contributing to anticancer potential against BC LC were identified through network pharmacology. present web servers UALCAN, GEPIA2, KM plotter used explore genomic proteomic expression of these targets, along with their prognosis in LC. Results Differential SRC, MAPK3, PTPN11, JAK2, ESR1, HAP900A1 for EGFR, MAPK3 LC, showed good prognostic...
Background: Melanoma is a highly destructive and lethal form of skin cancer. With the contemplation concept plant-based chemotherapeutic nanomedicine approach, this study aims to develop liposome standardized Piper longum L. fruit ethanolic extract (PLFEE), with evaluation its pharmaceutical properties cytotoxic activities against melanoma cell line. To our knowledge, no authentic reports are available for PLFEE-loaded therapy. Methods: The chemical marker-based standardization PLFEE was...
Background: Melanoma is the most aggressive and deadly form of skin cancer. The stratum corneum a major obstacle to dermal transdermal drug delivery. Ultradeformable nanovesicular transferosome has capacity for deeper penetration its incorporation into hydrogel forms transgelosome that better permeability patient compliance. Method: Here, quality-by-design-based development optimization standardized Piper longum fruit ethanolic extract (PLFEE) melanoma therapy are reported. Results: Compared...
Aim: This work aimed to develop Tinospora cordifolia stem-derived carbon dots (TCSCD) for cancer cell imaging, free radical scavenging and metal sensing applications. Method: The TCSCDs were synthesized by a simple, one-step, ecofriendly hydrothermal carbonization method characterized their optical properties, morphology, hydrodynamic size, surface functionality, crystallinity, stability, bacterial biocompatibility, in vitro cellular ability. Results: exhibited excellent biocompatibility...
Converting biowaste into a functional product is put to the test by growing amount of in world and environmental problems it causes. In this research study, we synthesized, characterized, evaluated bluish-green luminescent carbon nanodots (CNDs) from cow dung expired tomato sauces via hydrothermal synthesis method at 160 °C for 8 h. The were fabricated without additional passivating agents exhibited good physicochemical optical properties. intrinsic properties characterized using various...
The current study aims to develop and optimize microemulsions (ME) through Quality-by-Design (QbD) approach improve the aqueous solubility dissolution of poorly water-soluble drug disulfiram (DSF) for repurposing in melanoma breast cancer therapy.
Abstract The study aimed to enhance the solubility, dissolution, and oral bioavailability of standardized Piper longum fruits ethanolic extract (PLFEE) via fourth-generation ternary solid dispersion (SD) for melanoma therapy. With use solvent evaporation method, PLFEE was formulated into SD, optimized using Box-Wilson's Central Composite Design (CCD), evaluated pharmaceutical performance in-vivo anticancer activity against (B16F10) bearing C57BL/6 mice. SD showed good accelerated stability,...
Abstract Green synthesis of silver nanoparticles (AgNPs) using the Alysicarpus vaginalis alcoholic extract as a reducing agent and capping ligand was carried out. Notable peaks λ max 442–602 nm indicated reduction ions to elemental AgNPs. Particle size (Zavg) in range 32.3±0.76 252.3±0.342 nm). The negative Zeta potential (ZP, −2.9±0.31 −21.7±0.13 mV) low polydispersity index (PDI, 0.181±0.02 0.635±0.02) supported homogeneous nature Further, crystalline spherical AgNPs with smooth surface...
<title>Abstract</title> <bold>Purpose</bold> We used a notorious weed, <italic>Mikania micrantha</italic> (Asteraceae), to developed and optimize microwave-assisted quick, single-step, cost-effective, eco-friendly, safe approach for the biosynthesis of gold nanoparticles (AuNPs) investigate its antioxidant potential. <bold>Methods</bold> <italic>M. AuNPs (MMAuNPs) were produced in 75 seconds under microwave irradiation. The UV-Vis spectroscopy, SEM, HR-TEM, SAED, EDX, FTIR, XRD, DLS analysis...