A5002359598- Acne and Rosacea Treatments and Effects
- Autoimmune and Inflammatory Disorders
- Urticaria and Related Conditions
- Cancer and Skin Lesions
- Biometric Identification and Security
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Bacteriophages and microbial interactions
- Genetic and rare skin diseases.
- Climate Change and Health Impacts
- Dermatology and Skin Diseases
- Single-cell and spatial transcriptomics
- Skin Protection and Aging
- Gene expression and cancer classification
- Autoimmune Bullous Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Parvovirus B19 Infection Studies
- Plant and Fungal Interactions Research
- Plant Virus Research Studies
- Bioinformatics and Genomic Networks
- Hedgehog Signaling Pathway Studies
- Dermatological and COVID-19 studies
Shanghai Jiao Tong University
2024-2025
Ruijin Hospital
2024-2025
University of Hong Kong
2019-2020
Taipei Veterans General Hospital
2006
Abstract Background The effectiveness of botulinum toxin A (BoNTA) in the treatment Hailey-Hailey Disease (HHD) has shown heterogeneity recent studies. However, there is currently no research investigating underlying mechanism behind variability patient response. Objectives To identify potential biomarkers and elucidate mechanisms efficacy BoNTA for HHD. Methods Twelve HHD patients were administered standardized injections BoNTA, with primary endpoint being ≥ 75% improvement Improvement...
Single-cell RNA-Sequencing (scRNA-Seq), an advanced sequencing technique, enables biomedical researchers to characterize cell-specific gene expression profiles. Although studies have adapted machine learning algorithms cluster different cell populations for scRNA-Seq data, few existing methods utilized techniques investigate functional pathways in classifying heterogeneous populations. As genes often work interactively at the pathway level, studying cellular heterogeneity based on can...
The aim of this study was to identify key microbes associated with change in skin status (lesional vs normal). Longitudinal changes the microbiome between patients psoriasis and healthy family controls living same household were studied using whole genome metagenomic shotgun sequencing at 4 time-points. There significant abundance pathogen Campylobacter jejuni its higher taxonomic levels when changed. longitudinal variations alpha diveristy (p < 0.001) beta diversity 0.05) psoriasis, but not...