A5062851679- Photonic and Optical Devices
- Metamaterials and Metasurfaces Applications
- Photonic Crystals and Applications
- Orbital Angular Momentum in Optics
- Plasmonic and Surface Plasmon Research
- Electromagnetic Scattering and Analysis
- Advanced Antenna and Metasurface Technologies
- Electromagnetic Simulation and Numerical Methods
- Neural Networks and Reservoir Computing
- Random lasers and scattering media
- Microwave Engineering and Waveguides
- Optical Network Technologies
- Security and Verification in Computing
- Aortic Disease and Treatment Approaches
- Advanced Optical Imaging Technologies
- Glioma Diagnosis and Treatment
- Optical Coatings and Gratings
- Quantum optics and atomic interactions
- Advanced Fiber Optic Sensors
- Terahertz technology and applications
- Nonlinear Optical Materials Studies
- Physics of Superconductivity and Magnetism
- Aortic aneurysm repair treatments
- Infectious Aortic and Vascular Conditions
- Intelligent Tutoring Systems and Adaptive Learning
St. Jude Children's Research Hospital
2024-2025
Shanghai University
1996-2024
Anhui University
2016-2024
Shenzhen Institute of Information Technology
2024
Harbin Institute of Technology
2024
Wuhan National Laboratory for Optoelectronics
2023-2024
Huazhong University of Science and Technology
2023-2024
Southeast University
2023
Yanshan University
2023
Ministry of Education of the People's Republic of China
2021-2022
Multispectral and polarized focusing imaging are key functions that vitally important for a broad range of optical applications. Conventional techniques generally require multiple shots to unveil desired information implemented via bulky multi-pass systems or mechanically moving parts difficult integrate into compact integrated systems. Here, design ultra-compact transversely dispersive metalens capable both spectrum polarization ellipticity recognition reconstruction in just single shot is...
Cognitive Diagnosis Modeling aims to infer students' proficiency level on knowledge concepts from their response logs. Existing methods typically model students’ processes as the interaction between students and exercises or based hand-crafted deeply-learned functions. Despite promising achievements, they fail consider relationship cognitive states affective in learning, e.g., feelings of frustration, boredom, confusion with learning content, which is insufficient for comprehensive diagnosis...
Thoracic aortic dissection (TAD) is an aggressive vascular disease that requires early diagnosis and effective treatment. However, due to the particular structure narrowness of lesion location, there are no drug delivery systems for therapy TAD. Here, we report a multifunctional nanosystem (TP-Gd/miRNA-ColIV) composed gadolinium-chelated tannic acid (TA), low-toxic cationic PGEA (ethanolamine-aminated poly(glycidyl methacrylate)) type IV collagen targeted peptide (ColIV) nucleic therapy,...
Interactive holography offers unmatched levels of immersion and user engagement in the field future display. Despite substantial progress has been made dynamic meta-holography, realization real-time, highly smooth interactive remains a significant challenge due to computational display frame rate limitations. In this study, we introduced bitwise meta-holography with ultra-high rates. To our knowledge, is first reported practical metasurface holographic system. We spatially divided device...
Abstract Light beams possess various dimensions, such as wavelength, spin angular momentum (SAM), and orbital (OAM), which are indispensable in numerous optical applications. However, traditional techniques entail multiple attempts to disclose desired information, utilizing unwieldy multi‐pass systems or mechanically moving parts that cumbersome integrate into compact integrated systems. Here, a single‐layer dielectric metasurface platform is proposed enables multi‐dimensional demultiplexing...
Abstract 3D nanolithography based on two‐photon polymerization (TPP) allows for the high‐precision fabrication of nearly arbitrary micro/nanostructures, finding extensive applications in areas such as micro‐optics, micro‐mechanics, and biomedicine. However, large size, complexity optical systems, high costs have significantly constrained widespread adoption technology both scientific research industry. In this study, a metasurface is introduced, first time, into resulting construction...
Abstract Dynamic holography can reconstruct realistic and highly interactive 3D scenes, offering a promising way for future display. Emerging metasurface with small pixel size powerful light modulation capability demonstrates performance superior to traditional spatial modulators, but dynamic meta‐holography high information capacity frame rate remains challenge. This paper presents design scheme combining preset polarization‐dependent high‐speed projection module realize smooth display at...
An electrodynamic model is presented in this Letter to describe thresholdless lasers, utilizing the application of photonic time crystals (PTCs). By integrating distinctive physical properties PTCs and employing a comprehensive based on four-level system, feasibility achieving laser operation demonstrated. The proposed comprehensively captures intricate interplay between electromagnetic field PTC medium. takes into account ultrafast periodic variations refractive index PTCs, which arise from...
Thoracic aortic dissection (TAD) is an aggressive and life-threatening vascular disease there no effective means of early diagnosis dissection. Type IV collagen (Col-IV) a major component the sub-endothelial basement membrane, which initially exposed followed by endothelial injury as early-stage event TAD. So, we want to build noninvasive diagnostic method detect identifying Col-IV via MRI.
Abstract Background Pediatric-type diffuse high-grade glioma (pHGG) is the most frequent malignant brain tumor in children and can be subclassified into multiple entities. Fusion genes activating MET receptor tyrosine kinase often occur infant-type hemispheric (IHG) but also other pHGG are associated with devastating morbidity mortality. Methods To identify new treatment options, we established characterized two novel orthotopic mouse models harboring distinct fusions. These included an...
Abstract Homologous recombination deficiency (HRD) has been extensively studied in breast cancer and ovarian given its correlation with sensitivity to Poly (ADP-ribose) polymerases (PARP) inhibitors. In these cancers, HRD is most frequently caused by biallelic inactivation of BRCA1/2 tumors often exhibit ‘genomic scars’ (Nik-Zainal, 2016; Telli, Davies, 2017). Our group profiled a cohort 255 pediatric high-grade glioma (pHGG) patient samples for DNA damage response (DDR) gene variants...
We propose a stochastic hybrid implicit-explicit finite-difference time-domain method (S-HIE-FDTD) to compute the mean and variance of electromagnetic (EM) fields using single simulation, given those conductivity permittivity in computation domain. The field update equations underlying proposed are derived from "traditional" deterministic HIE-FDTD. Courant-Friedrichs-Lewy condition S-HIE-FDTD depends on spatial discretization sizes only two dimensions; therefore, for domains with fine...
Thoracic aortic aneurysm and dissection (TAAD) is a lethal cardiovascular condition without effective pharmaceutical therapy. Identifying novel drugs that target the key pathogenetic components an urgent need. Bioinformatics analysis of pathological studies indicated "extracellular matrix organization" as most significant functional pathway related to TAAD, in which metallopeptidase (MMP) 2 MMP9 ranked above other proteases. MMP1-14 were designated prototype molecules for docking against...
Metasurfaces, which possess unprecedented capabilities in manipulating electromagnetic wavefronts, are promising for accurate complex amplitude modulation with a compact device. However, current strategy of based on metasurfaces focuses anisotropic unit design is intrinsically constrained polarization states. In this study, we propose methodology polarization-independent metasurface comprises an array nanocylinders various radii and heights. The effectiveness the proposed scheme verified...
The numerical superiority of the unconditionally stable fundamental locally one-dimensional finite-difference time-domain (FLOD-FDTD) method has been proved in some studies. In this article, FLOD-FDTD is extended to simulate general dispersive media combination with auxiliary differential equation (ADE) scheme formulation based on electric field ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${E}$...
Previous research processes on topological insulators were mainly based the manual adjustment of a large number fine parameters to achieve desired properties. Here, we propose treat design process photonic crystals as an objective function through optimization theory, allowing properties arise spontaneously with optimization. Through topology optimization, have designed and implemented three different characteristics dual-band protection common bandgap. The results show that functional edge...
Abstract Chirality, one of the universal phenomena in physics, forms playground for fascinating modern electromagnetism and industrial applications. Within rapidly advancing technologies integrated optoelectronic all‐optical devices, controlling light flow on a chip using optical chiral modes emerges as crucial topic, which implies numerous counterintuitive chiroptical effects such unidirectional emission, magnetic‐free non‐reciprocity, switching, enhanced sensitivity. Here strong yet...
We propose and discuss a simple method to generate broadband optical vortices, utilizing the inherent topological vortex structures of polarization around bound states in continuum supported by photonic crystal slab momentum space induce generation beams. Since proposed structure is composed silicon pillars arranged periodically, it lacks true geometric center. It insensitive position incident light does not require specific alignment process compared traditional spiral phase plates....
All-dielectric metasurfaces offer unconventional optical functional behaviors for manipulating light, due to the strong localization of light with negligible dissipative loss. Here, we propose a compact design emission cavity consist an all-dielectric grating reflector and symmetry-breaking metasurface supporting "dark" mode. The mode asymmetric structure results in high quality factor, broadband perfect leads directional emission. We present theoretical study spectral characterization...