A5103224532- Liver Disease Diagnosis and Treatment
- Folate and B Vitamins Research
- IL-33, ST2, and ILC Pathways
- Immune Cell Function and Interaction
- Genetic Associations and Epidemiology
- Epigenetics and DNA Methylation
Qingdao University
2024
Affiliated Hospital of Qingdao University
2024
Abstract Prior research has established associations between immune cells, inflammatory proteins, and chronic kidney disease (CKD). Our Mendelian randomization study aims to elucidate the genetic causal relationships among these factors CKD. We applied using variants associated with CKD from a large genome-wide association (GWAS) markers comprehensive GWAS summary. The links exposures (immune cell subtypes proteins) were primarily analyzed inverse variance-weighted, supplemented by...
Chronic Kidney Disease (CKD) represents a global health challenge, with its etiology and underlying mechanisms yet to be fully elucidated. Integrating genomics metabolomics can offer insights into the putatively causal relationships between serum metabolites CKD.