A5040390320- Cancer Cells and Metastasis
- Blood groups and transfusion
- Molecular Biology Techniques and Applications
- Plant-Derived Bioactive Compounds
- Pharmacological Effects of Natural Compounds
- Craniofacial Disorders and Treatments
- Ocular Disorders and Treatments
- Spaceflight effects on biology
- Moyamoya disease diagnosis and treatment
- Genital Health and Disease
- Biological Stains and Phytochemicals
- Sexual function and dysfunction studies
- Natural product bioactivities and synthesis
- Cerebrovascular and genetic disorders
- Cancer, Lipids, and Metabolism
- Curcumin's Biomedical Applications
- Colorectal Cancer Treatments and Studies
- 3D Printing in Biomedical Research
- Mesenchymal stem cell research
- Erythrocyte Function and Pathophysiology
- Blood disorders and treatments
- Phytochemistry and Biological Activities
- Female Genital Mutilation/Cutting Issues
- Blood transfusion and management
- Metabolism, Diabetes, and Cancer
Pontificia Universidad Javeriana
2019-2024
Fundación Santa Fe de Bogotá
2021
Hospital Universitario Dexeus
2020
Interactions in the tumor microenvironment (TME) between cells and stromal such as cancer-associated fibroblasts (CAF) favor increased survival, progression, transformation of cancer by activating mechanisms invasion metastasis. The design new therapies to modulate or eliminate CAF phenotype functionality has been subject recent research including natural product-based therapies. We have previously described generation a standardized extract rich polyphenols obtained from Caesalpinia spinosa...
Cancer is understood as a multifactorial disease that involve multiple cell types and phenotypes in the tumor microenvironment (TME). The components of TME can interact directly or via soluble factors (cytokines, chemokines, growth factors, extracellular vesicles, etc.). Among cells composing TME, mesenchymal stem (MSCs) appear population with debated properties since it has been seen they both promote attenuate progression. For various authors, main mechanism interaction MSCs through their...
Tumor metabolism is a crucial aspect of cancer development, and mitochondria plays significant role in the aggressiveness metastasis tumors. As result, have become promising therapeutic target treatment, leading to development compounds known as mitocans. In our group, we consolidated search anticancer therapies based on natural products derived from plants, obtaining extracts such P2Et Caesalpinia spinosa Anamu-SC Petiveria alliacea, which been shown antitumor activities different models....
(1) Background: Female genital mutilation/cutting (FGM/C) is associated with physical and psychological complications. However, there scarce literature on how women FGM/C respond to treatment interventions. (2) Methods: In the present pilot longitudinal study, we assessed changes in general psychopathology (Symptom Check List-90-R), sexual functioning distress (Female Sexual Function Index, Distress Scale-Revised, Diagnostic Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)...
The characteristics of human hematopoietic stem cells are conditioned by the microenvironment bone marrow, where they interact with other cell populations, such as mesenchymal and endothelial cells; however, study this is complex. objective work was to develop a 3D culture system magnetic levitation that imitates HSC.Human marrow-mesenchymal cells, umbilical cord blood-hematopoietic non-tumoral line (CC2811, LonzaⓇ) were used organotypic multicellular spheres method. We obtained viable...
There are few case reports of hemolytic disease in fetuses and newborns (HDFN) caused by alloantibodies against the MNS blood group system. The reason for this dearth is that antibodies toward these antigens usually IgM, which not only cannot cross placental circulation but also react at temperatures below 37°C. They are, therefore, minimal clinical importance. Nevertheless, cases have been reported presence anti-M IgG severe HDFN even intrauterine death maternal-fetal incompatibility...
Colorectal cancer (CRC) is a prevalent and deadly tumor worldwide. Understanding the molecular mechanisms underlying CRC development will improve treatment outcomes patient survival. Natural molecules metabolites from plants, such as Tillandsia usneoides, reduce growth by modulating glucose metabolism increasing reactive oxygen species (ROS). To shed light on mechanism involved in anti-tumor effects of T. we evaluated cytotoxic effect ethanolic extract this plant colon cell line SW480...
Interactions in the tumor microenvironment (TME) between cells and stromal such as cancer-associated fibroblasts (CAF) favor increased survival, progression, transformation of cancer by activating mechanisms invasion metastasis. The design new therapies to modulate or eliminate CAF phenotype functionality has been subject recent research including natural product-based therapies. We have previously described generation a standardized extract rich polyphenols obtained from Cesalpinia spinosa...