A5059528478- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Advanced Combustion Engine Technologies
- Elasticity and Material Modeling
- Hydraulic and Pneumatic Systems
- Fluid Dynamics and Heat Transfer
- Combustion and flame dynamics
- Coronary Interventions and Diagnostics
- Vibration and Dynamic Analysis
- Nanofluid Flow and Heat Transfer
- Electrohydrodynamics and Fluid Dynamics
- Catalytic Processes in Materials Science
- Mechanical Circulatory Support Devices
- Cardiac Imaging and Diagnostics
- Heat Transfer and Boiling Studies
- Cardiovascular Health and Disease Prevention
- Spacecraft and Cryogenic Technologies
- Plant Surface Properties and Treatments
- Fluid Dynamics and Vibration Analysis
- Particle Dynamics in Fluid Flows
- Lattice Boltzmann Simulation Studies
- Atrial Fibrillation Management and Outcomes
- Aerosol Filtration and Electrostatic Precipitation
University of Glasgow
2016-2024
Beihang University
2017-2018
Computational modelling of whole-heart function is a useful tool to study heart mechanics and haemodynamics. Many existing models focus on electromechanical aspect without considering physiological valves use simplified fluid instead. In this we develop four-chamber model featuring realistic chamber geometry, detailed valve modelling, hyperelasticity with fibre architecture fluid–structure interaction analysis. Our used investigate behaviours different assumptions including restricted/free...
Understanding the interaction between valves and walls of heart is important in assessing subsequently treating dysfunction. This study presents an integrated model mitral valve (MV) coupled to left ventricle (LV), with geometry derived from vivo clinical magnetic resonance images. Numerical simulations using this MV–LV are developed immersed boundary/finite element method. The incorporates detailed valvular features, ventricular contraction, nonlinear soft tissue mechanics, fluid-mediated...
We present a coupled left atrium-mitral valve model based on computed tomography scans with fibre-reinforced hyperelastic materials. Fluid-structure interaction is realised by using an immersed boundary-finite element framework. Effects of pathological conditions, eg, mitral regurgitation and atrial fibrillation, geometric structural variations, namely, uniform vs non-uniform wall thickness rule-based atlas-based fibre architectures, the system are investigated. show that in case pulmonary...
Abstract Dysfunction of mitral valve causes morbidity and premature mortality remains a leading medical problem worldwide. Computational modelling aims to understand the biomechanics human could lead development new treatment, prevention diagnosis diseases. Compared with aortic valve, has been much less studied owing its highly complex structure strong interaction blood flow ventricles. However, interest in is growing, sophistication level increasing advanced computational technology imaging...
We develop a fluid-structure interaction (FSI) model of the mitral valve (MV) that uses an anatomically and physiologically realistic description MV leaflets chordae tendineae. Three different models-complex, 'pseudo-fibre' simplified chordae-are compared to determine how representations affect dynamics MV. The are modelled as fibre-reinforced hyperelastic materials, FSI is using immersed boundary-finite element method. first verified under static boundary conditions against commercial...
N-butanol has been recognized as a promising alternative fuel in gasoline engines and outstanding advantages over low-carbon alcohols terms of energy density miscibility. In this work, the comparative investigation on spray behaviors n-butanol was carried out using commercial direct injection (GDI) injector. The tests were high-pressure constant volume vessel with pressures from 6.0 to 15.0 MPa ambient 0.1 0.5 MPa. High speed imaging Phase Doppler Particle Analyzer (PDPA) techniques used...
Abstract This paper aims to investigate detailed mechanical interactions between the pulmonary haemodynamics and left heart function in pathophysiological situations (e.g. atrial fibrillation acute mitral regurgitation). is achieved by developing a complex computational framework for coupled circulation, atrium valve model. The are modelled with physiologically realistic three-dimensional geometries, fibre-reinforced hyperelastic materials fluid–structure interaction, vessels as...
Research on venous hemodynamics is pivotal for unravelling diseases, including varicose veins and deep vein thrombosis, essential clinical management, treatment artificial valve design. In this study, a three-dimensional (3D) numerical simulation, employing the immersed boundary/finite element method, constructed to explore fluid-structure interaction (FSI) between intravenous blood valves. A hyperelastic constitutive model used capture incompressible, nonlinear mechanical response. Our...
The planar surface area and the spray nonuniformity are important parameters for determining evaporation characteristics. In this study, effects of fuel compositions two process variables (the injection pressure axial distance from measurement plane to nozzle exit) on both were experimentally investigated via statistical extinction tomography. design experiment (DoE) was adopted procedure analyze data in a systematic way by establishing quadratic mixture models crossed with linear model....
The transient and time-averaged boiling heat transfer characteristics of water during density wave oscillations are studied experimentally. A horizontally positioned helical coiled tube is used as test section heated with alternating current. measurement the fluid temperatures at different positions within one cross indicate that departs from saturation, a significant superheat occurs, postdryout reached transient. It interesting same not oscillating in phase but rather delayed outer side to...
Understanding the interaction between valves and walls of heart is important in assessing subsequently treating dysfunction. With advancements cardiac imaging, nonlinear mechanics computational techniques, it now possible to explore valve-heart interactions using anatomically physiologically realistic models. This study presents an integrated model mitral valve (MV) coupled left ventricle (LV), with geometry derived from vivo clinical magnetic resonance images. Numerical simulations this...