Yuhan Zhao

ORCID: 0000-0003-3103-1929
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About
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Research Areas
  • Sulfur Compounds in Biology
  • Autophagy in Disease and Therapy
  • Phytochemical compounds biological activities
  • Mitochondrial Function and Pathology
  • Health disparities and outcomes
  • Arsenic contamination and mitigation
  • Vitamin C and Antioxidants Research
  • Liver Disease Diagnosis and Treatment
  • Phytochemistry and Bioactive Compounds
  • Histone Deacetylase Inhibitors Research
  • Psychological Well-being and Life Satisfaction
  • Aging and Gerontology Research
  • Insect and Pesticide Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Cardiac Ischemia and Reperfusion
  • Microbial Applications in Construction Materials
  • Cholinesterase and Neurodegenerative Diseases
  • Ginkgo biloba and Cashew Applications
  • Insects and Parasite Interactions
  • Ferroptosis and cancer prognosis
  • Ubiquitin and proteasome pathways
  • Chemical synthesis and alkaloids
  • Heme Oxygenase-1 and Carbon Monoxide
  • Antioxidant Activity and Oxidative Stress
  • PARP inhibition in cancer therapy

Kunming Institute of Botany
2020-2025

Chinese Academy of Sciences
2020-2025

Qingdao University of Science and Technology
2025

Qingdao University of Technology
2025

Shihezi University
2020-2022

Institute of Zoology
2020

Southwest University
2015

Ferroptosis is a non‑apoptotic form of cell death mediated by reactive oxygen species (ROS). Iron metabolism disorders play key role in sepsis‑induced cardiomyopathy (SIC). While hydrogen sulfide (H2S) inhibits SIC, it unknown if does so controlling ferroptosis. The present study evaluated whether sodium hydrosulfide (NaHS), an H2S donor, alleviates SIC decreasing Lipopolysaccharide (LPS) was employed to induce vitro model septic myocardial injury rat H9c2 cardiomyocytes. rats established...

10.3892/mmr.2022.12851 article EN cc-by-nc-nd Molecular Medicine Reports 2022-09-12

Abstract Amide herbicides (AHs) were disturbed urease (UA) activity and soil microbial community, caused nutrient changes. Activity of UA was inhibited by AHs via groups chlorine, benzene ring, peptide bond (-N-/-CO-). Difference surface charge distribution mainly derived from position to connected -Cl, distance -O- ether group -N bond, difference structure/length for hydrocarbon chain, different regions negative enrichment. Developmental toxicity (DT) alachlor strongest related smaller...

10.1093/etojnl/vgaf053 article EN other-oa Environmental Toxicology and Chemistry 2025-02-22

Four putative knockdown resistance (kdr) mutations have been documented in the voltage-gated sodium channel (VGSC) gene of Cimex hemipterus from several countries. However, no information regarding kdr any Chinese tropical bed bug population is available to date. In this study, a double-mutation(M918I + L1014F)kdr allele was identified six C. populations across Guangxi Zhuang Autonomous Region China. The frequency 100% all examined populations. addition, only two cytochrome c oxidase I (COI)...

10.1017/s0007485319000877 article EN Bulletin of Entomological Research 2020-02-10

Given the cardioprotective role of autophagy, this study aimed to investigate protective effect exogenous H2S (NaHS) on infectious cardiomyopathy through inhibition AMPK/mTOR pathway.In study, sepsis models were established by cecal ligation and puncture (CLP) induction in vivo intraperitoneal injection NaHS was performed. Autophagy- apoptosis-related proteins observed western blot, isolated myocardial tissue morphology hematoxylin-eosin (H&E) staining, apoptosis evaluated tunnel method. The...

10.1155/2022/8464082 article EN cc-by Contrast Media & Molecular Imaging 2022-01-01

To investigate the effect of hydrogen sulfide (H 2S) on reactive oxygen species (ROS)-mediated endoplasmic reticulum stress in myocardial injury caused by sepsis.A sepsis model was induced Sprague-Dawley (SD) rats cecal ligation and puncture (CLP). The were randomly divided into sham operation (sham) group, (CLP) sepsis+sodium hydrosulfide (NaHS) (CLP+NaHS) group. left ventricular function observed with echocardiography their plasma H 2S levels measured. Lactate dehydrogenase (LDH),...

10.12182/20220960106 article EN PubMed 2022-09-01

Morinda officinalis is a traditional Chinese tonic herb, and have been used in the treatment of multiple diseases. Here, three iridoid glycosides isolated from M. were evaluated for their roles autophagy-lysosomal pathway. All could induce TFEB/TFE3-mediated lysosomal biogenesis trigger autophagy. Interestingly, they promoted nuclear import TFEB/TFE3 without affecting export, suggesting role maintenance homeostasis. The results this study shed light on identification autophagy activators...

10.1080/10286020.2023.2269370 article EN Journal of Asian Natural Products Research 2023-10-27
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