A5053231722- Advanced Neuroimaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Transcranial Magnetic Stimulation Studies
- Meningioma and schwannoma management
- Cardiac Arrhythmias and Treatments
- Surgical Simulation and Training
- Spinal Hematomas and Complications
- Acute Ischemic Stroke Management
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cardiac Health and Mental Health
- Spinal Fractures and Fixation Techniques
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disorders and Treatments
- Alzheimer's disease research and treatments
- Spinal Dysraphism and Malformations
- Histone Deacetylase Inhibitors Research
- Neurological disorders and treatments
- Spine and Intervertebral Disc Pathology
- Reconstructive Surgery and Microvascular Techniques
- Cervical and Thoracic Myelopathy
- Heart Failure Treatment and Management
- Functional Brain Connectivity Studies
- Case Reports on Hematomas
- Regulation of Appetite and Obesity
King's College Hospital NHS Foundation Trust
2022-2025
King's College Hospital
2024
424 General Military Hospital
2021
National and Kapodistrian University of Athens
2018
MGMT promoter methylation is related to the increased sensitivity of tumour tissue chemotherapy with temozolomide (TMZ) and thus improved patient survival. However, it unclear how extent affects outcomes. In our study, a single-centre retrospective we explore impact in patients glioblastoma who were operated upon 5-ALA. Demographic, clinical histology data, survival rates assessed. A total 69 formed study group (mean age 53.75 ± 15.51 years old). Positive 5-ALA fluorescence was noted 79.41%....
Background Most of the randomized clinical trials that led to wide use non-vitamin K antagonist oral anticoagulants for stroke prevention in patients with atrial fibrillation (AF) originated from western countries. Aim To systematically review and quantitatively synthesize real-world data regarding efficacy safety dabigatran, rivaroxaban, apixaban compared warfarin Asian non-valvular AF. Methods Medline, Cochrane, ClinicalTrial.gov databases were reviewed. A random-effect model meta-analysis...
BACKGROUND: Spontaneous spinal epidural hematoma (SSEH) is a rare pathology, which carries significant morbidity. OBJECTIVE: To review our institutional experience of surgically managed patients with SSEH, seeking to better understand clinical prognostic factors related postoperative outcomes and thereby improve counseling before treatment. METHODS: All who underwent surgical management SSEH between September 2011 2021. Baseline radiological characteristics are presented, including the...
Surgical management of deep-seated brain tumors requires precise functional navigation and minimally invasive surgery. Preoperative mapping using navigated transcranial magnetic stimulation (nTMS), intraoperative neurophysiological monitoring (IONM), parafascicular surgery (MIPS) act together in a functional-sparing approach. nTMS also provides rehabilitation tool to maximize recovery. This is single-center retrospective proof-of-concept cohort study between January 2022 June 2023 patients...
Navigated repetitive transmagnetic stimulation is a non-invasive and safe brain activity modulation technique. When combined with the classical rehabilitation process in stroke patients it has potential to enhance overall neurologic recovery. We present case of peri-operative stroke, treated ultra-early low frequency navigated over contralesional hemisphere. The patient received within 12 hours onset for seven consecutive days significant improvement his right sided weakness was noticed he...
<title>Abstract</title> Background Neuroplasticity is well established in low grade glioma patients. Our case report demonstrates that it can occur even more aggressive brain lesions. Methods A 56-year-old lady presented with a recurrent speech deficit seventeen months after her initial craniotomy for language eloquent glioblastoma (GBM). Pre-operative navigated trans-cranial magnetic stimulation (n-TMS) mapping, tractography and intra-operative mapping were performed. Results During second...
Abstract BACKGROUND Glioblastoma multiforme (GBM) portends poor prognosis despite multiple attempts at finding newer therapies. The current standard of care remains maximal safe resection. 5-ALA guidance helps to maximise the resection extent but complete removal is not always possible. It unclear, if residual pattern can predict outcome patients with GBM. MATERIALS & METHODS Patients GBM treated our centre between January 2018 - July 2019 were included they had based tumour excision...
Hypertrophic pachymeningitis is a rare disorder of the dura mater spine or brain. It can be caused by inflammatory, infective neoplastic conditions idiopathic. We report man with hypertrophic and bilateral chronic subdural haematoma IgG4-related disease. highlight diagnostic challenges discuss possible underlying mechanisms formation in inflammatory conditions. Isolated very rare; previously reported cases have suggested predilection for men their sixth decade, presenting headache as...