A5101667405- Advanced Drug Delivery Systems
- Drug Solubulity and Delivery Systems
- Nanoparticle-Based Drug Delivery
- Polysaccharides Composition and Applications
- Computational Drug Discovery Methods
- Phytochemicals and Medicinal Plants
- RNA Interference and Gene Delivery
- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Pharmaceutical studies and practices
- Cholinesterase and Neurodegenerative Diseases
- Natural Antidiabetic Agents Studies
- Analytical Chemistry and Chromatography
- Pharmaceutical Economics and Policy
- Magnetic Properties and Synthesis of Ferrites
- Fungal Biology and Applications
- Plant-Derived Bioactive Compounds
- Advancements in Transdermal Drug Delivery
- Analytical Methods in Pharmaceuticals
- Nanoparticles: synthesis and applications
- Radiopharmaceutical Chemistry and Applications
- Biological Stains and Phytochemicals
- Advanced Optical Network Technologies
- Radiation Therapy and Dosimetry
- Diverse Scientific Research Studies
JSS Academy of Higher Education and Research
2013-2023
American Pharmacists Association
2018
Macquarie University
2017
Johannes Gutenberg University Mainz
2014
Shri Dharmasthala Manjunatheswara College of Ayurveda and Hospital
2013
Dr. Reddy's Foundation
2000
Key biologic effects of the alpha-particle emitter Actinium-225 in comparison to beta-particle Lutetium-177 labeled somatostatin-analogue DOTATOC vitro and vivo were studied evaluate significance γH2AX-foci formation.To determine relative biological effectiveness (RBE) between two isotopes (as - consequence different ionisation-densities along a particle-track), somatostatin expressing AR42J cells incubated with Ac-225-DOTATOC Lu-177-DOTATOC up 48 h viability was analyzed using MTT assay....
Nanobiotechnology has evolved as a promising technology in developing therapeutically active materials. This study involved the biological synthesis of silver nanoparticles (AgNPs) from extracellular filtrate fungal species Aspergillus fumigatus to assess their antioxidant and cytotoxic activity under in‐vitro conditions. method become more reliable than physical chemical approaches, attributed its use ecologically clean non‐toxic methods. These synthesized are then characterized by...
Background: The design of improved biomaterials for medication administration is vital in overcoming problems associated with standard therapy Helicobacter pylori (H. pylori)-induced stomach ulcers. This study aims to develop and characterize floating biomaterial levofloxacin microballoon based on a fluoroquinolone-benzoxazine system conjugated methylated piperazine carboxylic acid groups, strategically designed prolonged gastric delivery. Methodology: Using the emulsion solvent diffusion...
Nifedipine is a calcium channel blocker extensively used in the treatment of anginal and hypertension. On oral administration it undergoes extensive first pass metabolism, which outweighs its absorbance through gastrointestinal tract (GIT) bioavailability drug systemic circulation. As an alternative to route transdermal delivery was developed. In present investigation, proniosomes are prepared by varying ratio span-40, lecithin, aqueous phase polymer. Formulation containing isopropyl...
Epilepsy is one of the most common neurological disorders, characterized by recurrent spontaneous seizures and a major health problem that affects around 1-2 % population worldwide. The treatment generally includes antiepileptic drug therapies. However, despite development various drugs, about third patients are resistant to current pharmacotherapies. Non-drug therapies also expanding in an exciting unprecedented way since with resistance, non-drug like surgeries; implantable devices diet...
Natural and plant-based polymers could be used for control release of drugs also helps in targeting drug to the site action. The main objective present work was check feasibility plant-based, namely, mango gum polymeric nanoparticles (NPs) as a carrier central nervous system (CNS) delivery using model donepezil (DZP). NPs were prepared by modified ionic gelation method emulsion cross-linking method. Zeta sizer results showed that diameter about 90-130 nm. DZP-loaded almost spherical shape,...
The present research aimed at developing an injection-free nanoparticulated formulation in multiple emulsion form, for oral delivery of insulin, which otherwise undergoes degradation the gastric environment if administered orally. Insulin-polymeric nanoparticles were prepared using layer by (LbL) adsorption method and incorporated into to form a emulsion. Using 0.6 M sodium chloride, insulin nanoaggregates 300-400 nm size obtained about yield 94%. characteristics representative nanoparticle...
Hydrogel nanoparticles have gained attention in recent years as they demonstrate the features and characters of hydrogels at same time. In present study chitosan carrageenan been used, hydrogel mercaptopurine are developed using natural, biodegradable, biocompatible polymers like carrageenan. As these hydrophilic nature, particles will a long life span systemic circulation. with is form an antileukemia drug by counter polymer gelation method. Fourier-Transform Infrared (FT-IR) studies shown...
Diabetes mellitus is a group of metabolic diseases identified by hyper glycaemia that results from defects in insulin secretion, action or both. It can also be referred as disorder. The main objective this research to enhance the protection wound healing valsartan loaded Nanostructure Lipid carrier. Valsartan angiotensin II antagonist drug, which BCS class category. lipid carrier colloidal system having many advantages such improvement Bioavailability, Increase solubility and therapeutic...
Standardisation of polyherbal formulations is necessary for the quality, safety, quantity, and efficacy botanicals in marketed newly established formulations. The Ministry Ayush, Govt India, recommended using to treat COVID-19, i.e., Kabusura kudineer, Nilavembu etc., kudineer a Siddha-based formulation. It prevents treats COVID-19 due some which have proven anti-inflammatory, anti-viral, immunomodulatory effects. current work focuses on establishing standard protocol marketed, novel dosage...
High molecular weight hydroxypropyl methylcellulose (HPMC) and biodegradable pectin were used for coating the pellets containing curcumin, to be released in colon. The prepared freeflowing. vitro release of curcumin remained intact up pH 3.0, disintegrated at 7.2, 12 hours. ideal batch (1:3) showed minimum 1.2 maximum 6.8, an increased amount blood stream(1.287 μg/ml) was achieved when compared with pure (0.5 μg/ml). drug retarded by high concentrationand greater thickness HPMC on pellets....