A5001353801- Research on Leishmaniasis Studies
- Veterinary Oncology Research
- Leptospirosis research and findings
- Mesenchymal stem cell research
- Veterinary Medicine and Surgery
- Trypanosoma species research and implications
- Hernia repair and management
- Muscle and Compartmental Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Testicular diseases and treatments
- Veterinary Orthopedics and Neurology
- Renal and Vascular Pathologies
- Animal health and immunology
- SARS-CoV-2 detection and testing
- Veterinary Pharmacology and Anesthesia
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Dental Research and COVID-19
- Renal function and acid-base balance
- Traumatic Brain Injury and Neurovascular Disturbances
- Veterinary Equine Medical Research
- Cerebrovascular and Carotid Artery Diseases
- Biochemical and Molecular Research
- Chronic Kidney Disease and Diabetes
- Congenital heart defects research
Universidad de Extremadura
2015-2025
University of Guayaquil
2022-2024
Complejo Hospitalario de Cáceres
2019
Industrial University of Santander
2016
Leishmaniasis is a zoonotic disease caused by Leishmania spp., impacts multiple systems and organs. While hematological biochemical profiles aren't definitive for diagnosis, recent studies have identified the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR) systemic immune-inflammation index (SII) as predictors of morbidity mortality in critically ill human dog patients. This study examined 100 dogs diagnosed with leishmaniasis, categorized International Renal Interest...
Canine leishmaniasis (CanL) is a disease caused by Leishmania infantum that can vary from subclinical infection to severe disease. Dogs affected with CanL present varying degrees of renal dysfunction. Unfortunately, traditional biomarkers such as urea and creatinine detect damage in advanced stages the disease, so more accurate are needed. Hence, we aimed study how urinary cystatin C (CysC) N-acetyl-beta-D-glucosaminidase (NAG), behave dogs at different Eighty-six infected were classified...
Wastewater surveillance represents an alternative approach to regulating contamination and the early detection of infectious agents outbreaks diseases public health importance. This study evaluated domestic wastewater effects on recreational waters in estuarine seawater bodies Guayas Santa Elena provinces Ecuador, South America. Fecal indicator bacteria (thermotolerant coliforms) served as key indicators for evaluation. Physical, chemical, microbiological quality markers following Ecuadorian...
Mesenchymal stem cells have proven to be a promising alternative conventional steroids treat canine inflammatory bowel disease (IBD). However, their administration requires washout period of immunosuppressive drugs that can lead an exacerbation the symptoms. Therefore, feasibility and effects combined application prednisone in IBD-dogs without adequate response corticosteroids was evaluated for first time this study over long- term follow up. Two groups dogs with IBD, one treatment another...
Chronic kidney disease (CKD) is a major complication and the leading cause of mortality in canine leishmaniasis (CanL). The kidneys are essential for numerous metabolic processes, specific metabolites may serve as predictive biomarkers function. Nuclear Magnetic Resonance (NMR) spectroscopy prominent analytical tool metabolomics, capable identifying urine. This study aim to identify distinct patterns NMR spectra urine samples from dogs with CKD CanL, reflecting underlying profiles Fifty-five...
Adipose-derived mesenchymal stem cells (Ad-MSCs) exhibit anti-inflammatory and immunomodulatory activities. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), systemic immune-inflammation index (SII) have been reported as novel biomarkers of the inflammatory state; however, they never examined in dogs with chronic enteropathy (CIE) treated Ad-MSCs. This study aimed to compare clinical evolution changes NLR, PLR, SII CIE before after cell therapy. Sixteen were...
To investigate effects of exercise on hematologic and biochemical values (especially markers inflammation muscle damage) in Spanish Greyhounds used for hunting without previous training.32 31 dogs other breeds.Hematologic variables concentrations C-reactive protein (CRP) were compared samples obtained from 24 hours after (eg, a race) 2 months (ie, at rest) non-Spanish rest. All healthy. Hematologic analyses performed within obtained, results by means Student t test.CRP concentration enzyme...
Canine leishmaniosis (CanL), caused by Leishmania sp., presents a wide array of symptoms; renal dysfunction is frequently observed in these dogs and associated with poor prognosis increased mortality. The traditional biomarkers namely urea creatinine can detect damage but only advanced stages the disease. However, it has been shown that symmetric dimethylarginine assay (SDMA) or protein/creatinine ratio (UPC) are early dysfunction. Their elevation occurs earlier than creatinine, other novel...
Contents A 6‐year‐old female Alaska Malamute dog was presented for evaluation of abdominal enlargement referred by a local veterinarian. On the history, owner complained chronic initiated more than 4 months ago, reduced appetite, occasional vomiting and general dullness. He also greenish mucous intermittent vaginal discharge starting 10 days ago. The bitch chronically treated with medroxiprogesterone acetate. laparatomy performed fluid in abdomen found aspirated during surgery. Also very...
Insonation of Circle Willis by transcranial Doppler duplex color sonography is described in 30 healthy dogs with 15 weighing <33 lb and >33 lb. Imaging was via a temporal window to explore the rostral, middle, caudal cerebral arteries on both left right‐hand sides; through an suboccipital study basilar artery. Normal mean values peak systolic velocity (PSV), end diastolic velocity, resistance index (RI), pulsatility (PI) were characterized compared those obtained previous studies....
Background Oral administration of glucocorticoid alters serum cystatin C ( sC ysC) concentration in humans. Objective To determine if oral prednisone ysC dogs without pre‐existing renal disease. Animals Forty six were included: 10 diagnosed with steroid responsive meningitis arteritis SRMA ; group A), 20 pituitary‐dependent hyperadrenocorticism PDH B), and 16 healthy control (group C). Methods Retrospective observational study. administered 4 mg/kg/24 h PO 7 days, reducing the dose to 2 days...
Canine leishmaniosis is frequently associated with the development of renal disease. Its pathogenesis complex and not fully understood. For this reason, study aimed to describe urinary proteome, identify possible new biomarkers in dogs kidney disease secondary leishmaniosis. Urine samples were collected from 20 dogs, 5 healthy 15 stages Leishvet III IV. analyzed by UHPLC-MS/MS. The data are available via ProteomeXchange identifier PXD029165. A total 951 proteins obtained. After bioinformatic...
Abstract Leptospirosis is a globally distributed zoonosis with multisystemic involvement in canine species, capable of causing pulmonary hemorrhagic syndrome (LPHS) the most severe cases. In humans, neutrophil to lymphocyte ratio (NLR), platelets lymphocytes (PLR) and systemic immune-inflammation index (SII) have been described as predictors morbidity mortality various pathologies, but no such studies developed for leptospirosis. Hence, we aimed assess usefulness NLR, PLR SII dogs affected...
It has not been determined whether ileal appearance differs among dogs with chronic inflammatory enteropathy (CIE) and different serum concentrations of cobalamin.To compare endoscopic histologic findings in CIE cobalamin then evaluate the correlation changes to concentration using updated scoring systems assess ileum.Sixty-eight CIE.Retrospective study. Frequency features scores (IHS IES) were obtained compared severe hypocobalaminemia (SHC; <200 ng/L), (HC; 200-350 or normocobalaminemia...
The objective of our study was to search for survival biomarkers (SB) and treatment response monitoring (TRMB) in the urinary proteome dogs with renal disease secondary canine leishmaniosis (CanL), using UHPLC–MS/MS. proteomic data are available via ProteomeXchange identifier PXD042578. Initially, a group 12 evaluated divided into survivors (SG; n = 6) nonsurvivors (NSG; 6). A total 972 proteins were obtained from samples. Then, bioinformatic analysis reduced them 6 like potential SB...
Changes in blood flow the arteries of canine skull base following compression ipsilateral carotid artery were evaluated. Forty healthy conscious dogs evaluated during examination lateral recumbency. Using temporal window, rostral, middle and caudal cerebral The basilar was studied through suboccipital window. Following compression, pulse Doppler signal reduced or inverted when interrogating rostral artery, no change observed
The association between myocardial parasitic load (MPL) and cardiac biomarkers in Canine Leishmaniasis (CanL) has not been studied.Dogs with advanced CanL were prospectively recruited included if they euthanised. Prior to euthanasia these variables assessed: hematocrit, globulin, creatinine, N-terminal-pro brain natriuretic peptide (NT-proBNP), troponin I (cTnI), blood pressure, urine protein/creatinine ratio echocardiographic parameters. A left ventricular (LV) sample was taken for...