A5114375624- Wheat and Barley Genetics and Pathology
- Veterinary Medicine and Surgery
- Animal health and immunology
- Veterinary Equine Medical Research
- Plant Disease Resistance and Genetics
- Research on Leishmaniasis Studies
- Genetic Mapping and Diversity in Plants and Animals
- Renal and Vascular Pathologies
- Leptospirosis research and findings
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Congenital Diaphragmatic Hernia Studies
- Mesenchymal stem cell research
- Peroxisome Proliferator-Activated Receptors
- Paraquat toxicity studies and treatments
- Blood Coagulation and Thrombosis Mechanisms
- Veterinary Oncology Research
- Autophagy in Disease and Therapy
- Reproductive biology and impacts on aquatic species
- Soft tissue tumor case studies
- S100 Proteins and Annexins
- Muscle and Compartmental Disorders
- Veterinary medicine and infectious diseases
- Polyomavirus and related diseases
- Liver Disease Diagnosis and Treatment
Universidad de Extremadura
2006-2024
National Institutes of Health
2003-2004
National Institute of Diabetes and Digestive and Kidney Diseases
2003
Universidad Complutense de Madrid
1990-1994
Autophagy is a degradative mechanism involved in the recycling and turnover of cytoplasmic constituents from eukaryotic cells. This phenomenon autophagy has been observed neurons patients with Parkinson's disease (PD), suggesting functional role for neuronal cell death. On other hand, it demonstrated that exposure to pesticides can be risk factor incidence PD. In this sense, paraquat (PQ) (1,1′-dimethyl-4,4′-bipyridinium dichloride), widely used herbicide structurally similar known...
ABSTRACT. The podocyte plays a key role in glomerular function and disease. To facilitate studies of function, we have developed transgenic mouse model with inducible expression the podocyte. tetracycline-inducible system facilitates gene restricted cellular distribution tight temporal control. Recently, Bujard colleagues functionally improved reverse tetracycline–controlled transcriptional activator (rtTA) substantially lower background off state (the absence tetracycline) greater...
To investigate effects of exercise on hematologic and biochemical values (especially markers inflammation muscle damage) in Spanish Greyhounds used for hunting without previous training.32 31 dogs other breeds.Hematologic variables concentrations C-reactive protein (CRP) were compared samples obtained from 24 hours after (eg, a race) 2 months (ie, at rest) non-Spanish rest. All healthy. Hematologic analyses performed within obtained, results by means Student t test.CRP concentration enzyme...
Insonation of Circle Willis by transcranial Doppler duplex color sonography is described in 30 healthy dogs with 15 weighing <33 lb and >33 lb. Imaging was via a temporal window to explore the rostral, middle, caudal cerebral arteries on both left right‐hand sides; through an suboccipital study basilar artery. Normal mean values peak systolic velocity (PSV), end diastolic velocity, resistance index (RI), pulsatility (PI) were characterized compared those obtained previous studies....
Background Oral administration of glucocorticoid alters serum cystatin C ( sC ysC) concentration in humans. Objective To determine if oral prednisone ysC dogs without pre‐existing renal disease. Animals Forty six were included: 10 diagnosed with steroid responsive meningitis arteritis SRMA ; group A), 20 pituitary‐dependent hyperadrenocorticism PDH B), and 16 healthy control (group C). Methods Retrospective observational study. administered 4 mg/kg/24 h PO 7 days, reducing the dose to 2 days...
We performed experiments to test the suitability of squirrel monkeys (Saimiri sciureus) as an experimental model for BK virus (BKV) and simian 40 (SV40) infection. Four received intravenous inoculation with BKV Gardner strain, six SV40 777 strain. Eight 10 immunosuppression therapy, namely, cyclophosphamide subcutaneously either before or both after viral inoculation. The presence infection was assessed by quantitative real-time PCR amplification DNA from blood, urine, tissues. found that...
RESUMENLa electroforesis sérica en hojas de acetato celulosa es una técnica que se usa frecuentemente para separar las distintas fracciones proteicas.Esta permite detectar cambios cualitativos y cuantitativos proteínas séricas relacionados con enfermedades.El propósito este estudio fue caracterizar los producen proteicas caballos babesiosis el fin evaluar su aplicación diagnóstico la enfermedad.En trabajo han calculado concentraciones totales 53 ha realizado estos animales.Los fueron...
Canine leishmaniosis (CanL), caused by Leishmania sp., presents a wide array of symptoms; renal dysfunction is frequently observed in these dogs and associated with poor prognosis increased mortality. The traditional biomarkers namely urea creatinine can detect damage but only advanced stages the disease. However, it has been shown that symmetric dimethylarginine assay (SDMA) or protein/creatinine ratio (UPC) are early dysfunction. Their elevation occurs earlier than creatinine, other novel...
Changes in blood flow the arteries of canine skull base following compression ipsilateral carotid artery were evaluated. Forty healthy conscious dogs evaluated during examination lateral recumbency. Using temporal window, rostral, middle and caudal cerebral The basilar was studied through suboccipital window. Following compression, pulse Doppler signal reduced or inverted when interrogating rostral artery, no change observed
Our objectives were to standarize the procedure needed reproduce a similar surgical scene which pediatric surgeon would face on repairing Bochdalek hernia in newborns and define optimal time period for development that achieve realistic scenario with minimimal animal suffering. Twenty New Zealand white rabbits weighing 3-3.5 kg divided into four groups depending frame since creation thoracoscopic repair: 48 h, 72 96 h 30 days. trigono was identified procedures repair standarized. Blood...